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ADAMTS17 encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. 再加上，我们可以发ADAM Metallopeptidase with thrombospondin Type 1 Motif, 17 抗体 (22) 和 和数多这个蛋白质的别的产品。
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Secretion of ADAMTS17 requires O-fucosylation. ADAMTS17 binds fibrillin-2 (显示 FBN2 ELISA试剂盒) but not fibrillin-1 (显示 FBN1 ELISA试剂盒) and does not cleave either. ADAMTS17 regulates fibrillin isoform composition of microfibrils in the eye.
higher Adamts17 expression is found in several human cancer cell subtypes, especially in breast ductal carcinoma and there is an inverse correlation between higher Adamts17 expression and patients' survival.
A mutation in WMS (显示 FBN1 ELISA试剂盒)-like gene ADAMTS17 also causes WMS (显示 FBN1 ELISA试剂盒).
Endothelial protease nexin-1 (显示 SERPINE2 ELISA试剂盒) is a novel regulator of A disintegrin and metalloproteinase 17 (显示 ADAM17 ELISA试剂盒) maturation and endothelial protein C receptor (显示 PROCR ELISA试剂盒) shedding via furin (显示 FURIN ELISA试剂盒) inhibition.
Recessive ADAMTS17 mutations are a recurrent cause of isolated spherophakia with short stature.
ADAMTS17 is a target gene of the BACH1 (显示 BACH1 ELISA试剂盒) transcription factor according to ChIP-seq analysis in HEK (显示 EPHA3 ELISA试剂盒) 293 cells.
Homozygous mutation in ADAMTS17 causes lenticular myopia, ectopia lentis, glaucoma, spheropakia, and short stature.
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has a high sequence similarity to the protein encoded by ADAMTS19, another family member. The function of this protein has not been determined.
ADAM metallopeptidase with thrombospondin type 1 motif, 17
, disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 17
, A disintegrin and metalloproteinase with thrombospondin motifs 17
, ADAM-TS 17
, a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 17
, A disintegrin and metalloproteinase with thrombospondin motifs 17-like