ADAM Metallopeptidase Domain 22 (ADAM22) ELISA试剂盒

ADAM22 encodes a member of the ADAM (a disintegrin and metalloprotease domain) family.

list all ELISA KIts 基因 基因ID UniProt
小鼠 ADAM22 ADAM22 11496 Q9R1V6
大鼠 ADAM22 ADAM22 57033  
 ADAM22 ADAM22 53616 Q9P0K1
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0.058 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Log in to see 13至16个工作日
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适于 ADAM22 相互作用对的更多 ELISA 试剂盒

Mouse (Murine) ADAM Metallopeptidase Domain 22 (ADAM22) interaction partners

  1. LGI1 (显示 LGI1 ELISA试剂盒) and ADAM22 form an essential synaptic organizing complex that coordinates the maturation of excitatory synapses by regulating the functional incorporation of PSD-95 (显示 DLG4 ELISA试剂盒)

  2. Interaction proteomics revealed the interactors of Caspr2, including CNTN2, KCNAs, members of the ADAM family (ADAM22, ADAM23 and ADAM11), members of LGI family and MAGUKs (DLGs and MPPs).

  3. ADAM22 is an axonal component of the Kv1 (显示 KCNA5 ELISA试剂盒) K+ channel complex that recruits membrane-associated guanylate kinase (显示 GUK1 ELISA试剂盒) to juxtaparanodes

  4. ADAM22 is closely involved in the correct functioning of the nervous system.

  5. study identified LGI1 (显示 LGI1 ELISA试剂盒) as a specific binding partner of ADAM22 protein from mouse brain, and demonstrated the specific interaction between LGI1 (显示 LGI1 ELISA试剂盒) and ADAM22

Human ADAM Metallopeptidase Domain 22 (ADAM22) interaction partners

  1. these results support the existence of a second mechanism, alternative to inhibition of protein secretion, by which ADLTE (显示 LGI1 ELISA试剂盒)-causing LGI1 (显示 LGI1 ELISA试剂盒) mutations exert their loss-of-function effect extracellularly, and suggest that interactions of LGI1 (显示 LGI1 ELISA试剂盒) with both ADAM22 and ADAM23 (显示 Adam23 ELISA试剂盒) play an important role in the molecular mechanisms leading to utosomal dominant lateral temporal epilepsy

  2. Disruption of LGI1 (显示 LGI1 ELISA试剂盒)-ADAM22 interaction reduces synaptic AMPA (显示 GRIA3 ELISA试剂盒) receptors in hippocampal neurons.

  3. Data suggest that ADAM22 plays roles in cell differentiation, cell migration, and resistance to endocrine therapy in breast cancer; ADAM22 may serve as biomarker for poor disease-free survival in breast cancer patients. [REVIEW]

  4. findings suggest that SRC-1 (显示 SRC ELISA试剂盒) switches steroid-responsive tumors to a steroid-resistant state in which the SRC-1 (显示 SRC ELISA试剂盒) target gene ADAM22 has a critical role

  5. Mutations in disintegrin domain sequence in ADAM22 gene is associted with reduced LGI4-binding abilities resulting in epilepsy.

  6. Transgenic leucine-rich glioma-inactivated 4 (Lgi4) and transgenic Adam22 proteins are both expressed in Schwann cells as well as in sensory neurons; binding of Lgi4 to axonal Adam22 is required on axons to drive myelin formation.

  7. role for the 14-3-3zeta (显示 YWHAZ ELISA试剂盒)/ADAM 22 association in the regulation of cell adhesion and related signaling events

  8. demonstrated a functional role for ADAM22/14-3-3 (显示 YWHAQ ELISA试剂盒) in cell adhesion and spreading

  9. ADAM22, a brain-specific cell surface protein (显示 CD28 ELISA试剂盒), mediates growth inhibition using an integrin dependent pathway. It is expressed in normal brain but not in high-grade gliomas.

  10. This study indicated ADAM22 gene is probably not a major gene for this epilepsy syndrome.

ADAM22 抗原简介

Antigen Summary

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. Unlike other members of the ADAM protein family, the protein encoded by this gene lacks metalloprotease activity since it has no zinc-binding motif. This gene is highly expressed in the brain and may function as an integrin ligand in the brain. In mice, it has been shown to be essential for correct myelination in the peripheral nervous system. Alternative splicing results in several transcript variants.

Gene names and symbols associated with ADAM22

  • a disintegrin and metallopeptidase domain 22 (Adam22) 抗体
  • ADAM metallopeptidase domain 22 (Adam22) 抗体
  • ADAM metallopeptidase domain 22 (ADAM22) 抗体
  • ADAM metallopeptidase domain 22 L homeolog (adam22.L) 抗体
  • 2900022I03Rik 抗体
  • ADAM 22 抗体
  • AI854032 抗体
  • mdc2 抗体
  • mdc11b 抗体

Protein level used designations for ADAM22

a disintegrin and metalloprotease domain (ADAM) 22 , disintegrin and metalloproteinase domain-containing protein 22 , a disintegrin and metalloprotease domain 22 , a disintegrin and metalloproteinase domain 22 , metalloproteinase-disintegrin ADAM22-3 , metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2 , ADAM 22 , MDC11.2 , metalloprotease-disintegrin MDC11b , metalloprotease/disintegrin xMDC11.2

GENE ID SPECIES
11496 Mus musculus
57033 Rattus norvegicus
53616 Homo sapiens
386621 Xenopus laevis
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