ADAM Metallopeptidase Domain 15 (ADAM15) ELISA试剂盒

The protein encoded by ADAM15 is a member of the ADAM (a disintegrin and metalloproteinase) protein family. 再加上,我们可以发ADAM15 抗体 (111)ADAM15 蛋白 (13)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
ADAM15 11490 O88839
ADAM15 8751 Q13444
ADAM15 57025 Q9QYV0
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0.055 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Log in to see 13至16个工作日
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小鼠 4.69 pg/mL 18.75-1200 pg/mL Typical standard curve 96 Tests Log in to see 15至18个工作日
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大鼠 0.06 ng/mL n/a   96 Tests Log in to see 15至18个工作日
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1.0 pg/mL 250-5000 pg/mL   96 Tests Log in to see 15至18个工作日
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1.0 pg/mL 250-5000 pg/mL   96 Tests Log in to see 15至18个工作日
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< 0.054 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests Log in to see 11至18个工作日
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适于 ADAM15 相互作用对的更多 ELISA 试剂盒

Rabbit ADAM Metallopeptidase Domain 15 (ADAM15) interaction partners

  1. ADAM15 attenuates the progression of atherosclerosis; in contrast, a mutated form of ADAM15, created by ablation of the protease function, has no significant effect on atherosclerosis.

Mouse (Murine) ADAM Metallopeptidase Domain 15 (ADAM15) interaction partners

  1. findings indicated that silencing ADAM15 had antiinflammatory effects in FLSs and efficiently inhibited the development of CIA.

  2. the catalytic activity of ADAM15 is not crucial for its function in promoting pathological neovascularization in the mouse OIR model, most likely because of the very limited substrate repertoire of ADAM15.

  3. ADAM15 upregulation contributes to inflammatory lung injury by promoting endothelial hyperpermeability and neutrophil transmigration.

  4. A disintegrin and metalloproteinase 15 contributes to atherosclerosis by mediating endothelial barrier dysfunction via Src (显示 SRC ELISA试剂盒) family kinase activity.

  5. Adult Adam15(-/-) mice displayed an increase in bone volume and thickness with an increase in the number and activity of osteoblasts, whereas osteoclasts were apparently unaffected.

  6. ADAM15 has a role in pathological neovascularization in mice

  7. cytoplasmic domain of ADAM15v2 strongly interacts with Lck (显示 LCK ELISA试剂盒) and plays an important role in T lymphocytes

  8. The accelerated development of murine osteoarthritis in ADAM15 deficiency and the proadhesive and cell survival-promoting in vitro effect of ADAM15 overexpression suggest a homeostatic role of ADAM15 in cartilage remodeling.

  9. observations suggest that a disintegrin and metalloproteinase (ADAM)-8,-9,-10,-12,-15,and -17 play an important role in mouse uterine tissue remodelling during the oestrous cycle

  10. found modest expression of ADAM15 in pericytes in normal retina and strong up-regulation of ADAM15 in retinal vascular endothelial cells in ischemic retina

Human ADAM Metallopeptidase Domain 15 (ADAM15) interaction partners

  1. The results of our study demonstrate that ADAM15 is strongly up regulated in a small but highly aggressive fraction of prostate cancers.

  2. Data show that ADAM9 (显示 ADAM9 ELISA试剂盒) silencing affected MMP2 (显示 MMP2 ELISA试剂盒) and ADAM15 expression.

  3. ADAM15 promotes lung cancer cell invasion through directly targeting MMP9 (显示 MMP9 ELISA试剂盒) activation.

  4. the results revealed an undescribed role of ADAM15 in the invasion of human bladder cancer and suggested that the ADAM15 catalytic domain may represent a viable therapeutic target in patients with advanced disease.

  5. present a tumor suppressive mechanism for ADAM15 exosomes and provide insight into the functional significance of exosomes that generate tumor-inhibitory factors

  6. these data suggest the potential role of miR147b in regulating endothelial barrier function by targeting ADAM15 expression.

  7. findings indicated that silencing ADAM15 had antiinflammatory effects in FLSs and efficiently inhibited the development of CIA.

  8. The severity of intrauterine adhesions positively correlates to the protein and transcript expression levels of ADAM-15 and ADAM-17 (显示 ADAM17 ELISA试剂盒) in uterine tissue.

  9. ADAM15 contributes to apoptosis resistance in rheumatoid arthritis synovial fibroblasts by activating the Src (显示 SRC ELISA试剂盒)/FAK (显示 PTK2 ELISA试剂盒) pathway upon FasL (显示 FASL ELISA试剂盒) exposure.

  10. ADAM15 acts as a negative regulator of TRIF (显示 TRIM69 ELISA试剂盒)-mediated NF-kappaB (显示 NFKB1 ELISA试剂盒) and IFN-beta (显示 IFNB1 ELISA试剂盒) reporter gene activity via TLR3 (显示 TLR3 ELISA试剂盒) and TLR4 (显示 TLR4 ELISA试剂盒) signaling.

ADAM15 抗原简介

Antigen Summary

The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.

Gene names and symbols associated with ADAM15

  • ADAM metallopeptidase domain 15 (ADAM15) 抗体
  • ADAM metallopeptidase domain 15 L homeolog (adam15.L) 抗体
  • ADAM metallopeptidase domain 15 (adam15) 抗体
  • a disintegrin and metallopeptidase domain 15 (metargidin) (Adam15) 抗体
  • ADAM metallopeptidase domain 15 (Adam15) 抗体
  • ADAM15 抗体
  • MDC15 抗体
  • metargidin 抗体
  • tMDCVI 抗体

Protein level used designations for ADAM15

ADAM metallopeptidase domain 15 , a disintegrin and metalloproteinase domain 15 , metalloproteinase ADAM15 , disintegrin and metalloproteinase domain-containing protein 15-like , AD56 , ADAM 15 , MDC-15 , a disintegrin and metalloprotease domain 15 (metargidin) , a disintegrin and metalloproteinase domain 15 (metargidin) , disintegrin and metalloprotease 15 , disintegrin and metalloproteinase domain-containing protein 15 , metalloprotease RGD disintegrin protein , metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15 , CRII-7 , a disintegrin and metallopeptidase domain 15 (metargidin) , metargidin , tMDC VI

GENE ID SPECIES
457354 Pan troglodytes
490434 Canis lupus familiaris
100101326 Xenopus laevis
100145641 Xenopus (Silurana) tropicalis
100339079 Oryctolagus cuniculus
100393011 Callithrix jacchus
100468507 Ailuropoda melanoleuca
11490 Mus musculus
8751 Homo sapiens
784605 Bos taurus
57025 Rattus norvegicus
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