ATIC 抗体
(5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase (ATIC))
This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria. [provided by RefSeq, Sep 2009].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| ATIC 抗体 | 人 | 小鼠 Monoclonal |
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| ATIC 抗体 (AA 301-592) | 人 | 兔 Polyclonal |
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| ATIC 抗体 | 人 | 小鼠 Monoclonal |
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| ATIC 抗体 | 人 | 兔 Polyclonal |
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| ATIC 抗体 (Middle Region) | 人, 小鼠, 大鼠, 犬 | 兔 Polyclonal |
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| ATIC 抗体 | 人, 小鼠, 大鼠, 犬, 猴 | 小鼠 Monoclonal |
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| ATIC 抗体 (AA 379-428) | 人, 小鼠, 大鼠, 犬, 兔, 马, Cow, Pig, 豚鼠, Hamster, Bat | 兔 Polyclonal |
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| ATIC 抗体 | 人, 犬, 兔, 马, Cow, Pig, 猴, Drosophila melanogaster, 非洲爪蟾 | 小鼠 Monoclonal |
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| ATIC 抗体 | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| ATIC 抗体 | 人, 犬 | 小鼠 Monoclonal |
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| ATIC 抗体 | 人, 小鼠, 大鼠, 犬, 猴 | 小鼠 Monoclonal |
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| ATIC 抗体 (AA 1-592) | 人 | 兔 Polyclonal |
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| ATIC 抗体 (AA 1-592) | 人 | 小鼠 Polyclonal |
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| ATIC 抗体 | 人, 小鼠, 大鼠, Drosophila melanogaster, Frog | 小鼠 Monoclonal |
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| ATIC 抗体 (AA 151-200) | 人, 小鼠, 兔, Pig, 豚鼠, Drosophila melanogaster, 斑马鱼, Hamster | 兔 Polyclonal |
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| ATIC 抗体 (AA 1-300) | 人 | 兔 Polyclonal |
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| ATIC 抗体 (C-Term) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| ATIC 抗体 (AA 50-100) | 人, 小鼠 | 兔 Polyclonal |
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| ATIC 抗体 (AA 375-425) | 人, 小鼠 | 兔 Polyclonal |
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| ATIC 抗体 (N-Term) | 人, 小鼠 | 兔 Polyclonal |
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Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 301-592
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- 适用
- 人, 小鼠, 大鼠, 犬
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- Middle Region
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 适用
- 人, 小鼠, 大鼠, 犬, 兔, 马, Cow, Pig, 豚鼠, Hamster, Bat
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 379-428
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- WB (Western Blotting: 所列应用)
- 适用
- 人, 犬, 兔, 马, Cow, Pig, 猴, Drosophila melanogaster, 非洲爪蟾
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- F38 P7 H9
- 标记
- unconjugated
- 抗体亚型
- IgG1
Primary Antibody
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
1 reference - 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IP (Immunoprecipitation: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 1-592
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 1-592
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1-300
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- C-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IP (Immunoprecipitation: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 50-100
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 375-425
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- N-Term
Latest Publications for our ATIC 抗体
: "Diverse Inhibitors of De Novo Purine Synthesis Promote AICAR-Induced AMPK Activation and Glucose Uptake in L6 Myotubes." in: BioFactors (Oxford, England), Vol. 51, Issue 4, pp. e70037, (2025) (PubMed).
: "Mass spectrometric/bioinformatic identification of a protein subset that characterizes the cellular activity of anticancer peptides." in: Journal of proteome research, Vol. 13, Issue 11, pp. 5250-61, (2014) (PubMed).
: "5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside inhibits cancer cell proliferation in vitro and in vivo via AMP-activated protein kinase." in: The Journal of biological chemistry, Vol. 280, Issue 47, pp. 39582-93, (2005) (PubMed).
: "AICA-ribosiduria: a novel, neurologically devastating inborn error of purine biosynthesis caused by mutation of ATIC." in: American journal of human genetics, Vol. 74, Issue 6, pp. 1276-81, (2004) (PubMed).
: "The kinetic mechanism of the human bifunctional enzyme ATIC (5-amino-4-imidazolecarboxamide ribonucleotide transformylase/inosine 5'-monophosphate cyclohydrolase). A surprising lack of substrate ..." in: The Journal of biological chemistry, Vol. 277, Issue 25, pp. 22168-74, (2002) (PubMed).
: "Mass spectrometric/bioinformatic identification of a protein subset that characterizes the cellular activity of anticancer peptides." in: Journal of proteome research, Vol. 13, Issue 11, pp. 5250-61, (2014) (PubMed).
: "5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside inhibits cancer cell proliferation in vitro and in vivo via AMP-activated protein kinase." in: The Journal of biological chemistry, Vol. 280, Issue 47, pp. 39582-93, (2005) (PubMed).
: "AICA-ribosiduria: a novel, neurologically devastating inborn error of purine biosynthesis caused by mutation of ATIC." in: American journal of human genetics, Vol. 74, Issue 6, pp. 1276-81, (2004) (PubMed).
: "The kinetic mechanism of the human bifunctional enzyme ATIC (5-amino-4-imidazolecarboxamide ribonucleotide transformylase/inosine 5'-monophosphate cyclohydrolase). A surprising lack of substrate ..." in: The Journal of biological chemistry, Vol. 277, Issue 25, pp. 22168-74, (2002) (PubMed).
Aliases for ATIC 抗体
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase L homeolog (atic.L) 抗体bifunctional purine biosynthesis protein PurH (purH) 抗体
bifunctional purine biosynthesis protein purH (purH) 抗体
Bifunctional purine biosynthesis protein purH (purH) 抗体
Bifunctional purine biosynthesis protein PurH (purH) 抗体
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (ATIC) 抗体
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (Atic) 抗体
2610509C24Rik 抗体
AA536954 抗体
AICAR 抗体
AICARFT 抗体
AW212393 抗体
IMPCHASE 抗体
PURH 抗体
purH 抗体
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