(Ankyrin Repeat and BTB (POZ) Domain Containing 1 (ABTB1))
This gene encodes a protein with an ankyrin repeat region and two BTB/POZ domains, which are thought to be involved in protein-protein interactions. Expression of this gene is activated by the phosphatase and tensin homolog, a tumor suppressor. Alternate splicing results in three transcript variants. [provided by RefSeq, Mar 2010].
Unoki, Nakamura: "Growth-suppressive effects of BPOZ and EGR2, two genes involved in the PTEN signaling pathway." in: Oncogene, Vol. 20, Issue 33, pp. 4457-65, (2001) (PubMed).