(Amiloride Binding Protein 1 (Amine Oxidase (Copper-Containing)) (ABP1))
This gene encodes a metal-binding membrane glycoprotein that oxidatively deaminates putrescine, histamine, and related compounds. The encoded protein is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2013].
Liang, Zhao, Deng, Tian, Lei, Xu, Zhang, Su, Yang: "Estrogen regulates amiloride-binding protein 1 through CCAAT/enhancer-binding protein-beta in mouse uterus during embryo implantation and decidualization." in: Endocrinology, Vol. 151, Issue 10, pp. 5007-16, (2010) (PubMed).
Boomsma, Pedersen-Bjergaard, Agerholm-Larsen, Hut, Dhamrait, Thorsteinsson, van den Meiracker: "Association between plasma activities of semicarbazide-sensitive amine oxidase and angiotensin-converting enzyme in patients with type 1 diabetes mellitus." in: Diabetologia, Vol. 48, Issue 5, pp. 1002-7, (2005) (PubMed).