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ABCC8 抗体

(ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 (ABCC8))
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a modulator of ATP-sensitive potassium channels and insulin release. Mutations and deficiencies in this protein have been observed in patients with hyperinsulinemic hypoglycemia of infancy, an autosomal recessive disorder of unregulated and high insulin secretion. Mutations have also been associated with non-insulin-dependent diabetes mellitus type II, an autosomal dominant disease of defective insulin secretion. Alternative splicing of this gene has been observed\; however, the transcript variants have not been fully described. [provided by RefSeq, Jul 2008].

48 results

ABCC8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6136367
 
ABCC8 适用: 人 ELISA 宿主: 兔 Polyclonal HRP
产品编号 ABIN7144907
 
ABCC8 适用: 人 宿主: 兔 Polyclonal FITC
产品编号 ABIN7144906
 
ABCC8 适用: 人 ELISA 宿主: 兔 Polyclonal Biotin
产品编号 ABIN7144905
 
ABCC8 适用: 人 WB, IHC, ICC, IP 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN7635168
 
ABCC8 适用: 人, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6388663
 
ABCC8 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7568206
 
ABCC8 WB, IHC 宿主: 小鼠 Monoclonal N289-16 unconjugated Recombinant Antibody
产品编号 ABIN7574192
 
ABCC8 适用: 大鼠, 小鼠, Hamster WB, IHC, ICC 宿主: 小鼠 Monoclonal S289-16 unconjugated
产品编号 ABIN2613750
 
ABCC8 适用: 人, 大鼠, 小鼠 WB, IHC, ICC, FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5693055
 
ABCC8 适用: 人, 大鼠, 小鼠 WB, FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5708360
 
ABCC8 适用: 人 FACS 宿主: 兔 Polyclonal DyLight 550
产品编号 ABIN7354560
 
ABCC8 适用: 人 FACS 宿主: 兔 Polyclonal DyLight 488
产品编号 ABIN7354557
 
ABCC8 适用: 人 WB, ELISA 宿主: 兔 Polyclonal Biotin
产品编号 ABIN5558167
 
ABCC8 适用: 人 WB, ELISA 宿主: 兔 Polyclonal FITC
产品编号 ABIN2751625
 
ABCC8 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7612447
 
ABCC8 适用: 人 ELISA 宿主: 兔 Polyclonal FITC
产品编号 ABIN6108393
 
ABCC8 适用: 哺乳动物 WB, IHC, ISt 宿主: 小鼠 Monoclonal N289-16 unconjugated
产品编号 ABIN1304972
 
ABCC8 适用: 人 宿主: 兔 Polyclonal Alexa Fluor 555
产品编号 ABIN6889885
 
ABCC8 适用: 人 宿主: 兔 Polyclonal Alexa Fluor 647
产品编号 ABIN6916499
 
  • 类型 Primary
    • Primary
  • 应用范围
    • Western Blotting (WB)
    • Immunohistochemistry (IHC)
    • ELISA
    • Immunocytochemistry (ICC)
    • Immunofluorescence (IF)
    • Flow Cytometry (FACS)
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    • Immunohistochemistry (Frozen Sections) (IHC (fro))
    • Immunoprecipitation (IP)
    • Immunochromatography (IC)
    • Immunostaining (ISt)
    • Immunofluorescence (fixed cells) (IF/ICC)
  • 适用
    • Human
    • Rat
    • Mouse
    • Cow
    • Pig
    • Rabbit
    • Bat
    • Dog
    • Hamster
    • Mammalian
    • Monkey
    • Zebrafish (Danio rerio)
  • 论文引用
  • 图像
  • Carrier free only
  • 抗体来源
    • Rabbit
    • Mouse
    • Goat
  • 克隆形成能力
    • Polyclonal
    • Monoclonal
  • 克隆
    • S289-16
    • 3G5
    • N289-16
    • 3E1
  • 抗原表位
    • AA 1548-1582
    • AA 729-838
    • AA 611-710
    • AA 679-929
    • C-Term
    • N-Term
    • AA 301-400
    • AA 500-580
    • AA 611-711
    • AA 700-1000
  • 标记
    • 非结合性
    • FITC
    • Biotin
    • HRP
    • APC
    • Alexa Fluor 488
    • Alexa Fluor 555
    • Alexa Fluor 594
    • Alexa Fluor 647
    • Alexa Fluor 680
    • Alexa Fluor 750
    • Atto 390
    • Atto 488
    • Atto 594
    • DyLight 488
    • DyLight 550
    • PE
    • PerCP
  • 抗体亚型
    • IgG
    • IgG1
    • IgG2a kappa
    • IgG2a
    • kappa
  • 蛋白类型
    • Recombinant Antibody
  • Format
    • Liquid
    • Lyophilized
  • Grade
    • Verified
  • Supplier
    • antibodies-online
    • Signalway
    • Boster Bio
    • Abbexa
    • FabGennix
    • USBio
    • Antibodies Incorporated
    • Aviva Systems Biology
    • Biomatik
    • Covalab
    • NSJ Bioreagents

Latest Publications for our ABCC8 抗体

Gerzanich, Stokum, Ivanova, Woo, Tsymbalyuk, Sharma, Akkentli, Imran, Aarabi, Sahuquillo, Simard: "Sulfonylurea Receptor 1, Transient Receptor Potential Cation Channel Subfamily M Member 4, and KIR6.2:Role in Hemorrhagic Progression of Contusion." in: Journal of neurotrauma, Vol. 36, Issue 7, pp. 1060-1079, (2019) (PubMed).

Luu, Bjork, Salo, Entenmann, Jurgenson, Fisher, Klein: "Modulation of SUR1 KATP Channel Subunit Activity in the Peripheral Nervous System Reduces Mechanical Hyperalgesia after Nerve Injury in Mice." in: International journal of molecular sciences, Vol. 20, Issue 9, (2019) (PubMed).

Vázquez-Sánchez, Hinojosa, Parraguirre-Martínez, González, Morales, Montalvo, Vera, Hernández-Gallegos, Camacho: "Expression of KATP channels in human cervical cancer: Potential tools for diagnosis and therapy." in: Oncology letters, Vol. 15, Issue 5, pp. 6302-6308, (2018) (PubMed).

Němcová-Fürstová, Kopperová, Balušíková, Ehrlichová, Brynychová, Václavíková, Daniel, Souček, Kovář: "Characterization of acquired paclitaxel resistance of breast cancer cells and involvement of ABC transporters." in: Toxicology and applied pharmacology, Vol. 310, pp. 215-228, (2016) (PubMed).

Harel, Cohen, Hussain, Flanagan, Schlade-Bartusiak, Patel, Courtade, Li, Van Karnebeek, Kurata, Ellard, Chanoine, Gibson: "Alternating hypoglycemia and hyperglycemia in a toddler with a homozygous p.R1419H ABCC8 mutation: an unusual clinical picture." in: Journal of pediatric endocrinology & metabolism : JPEM, Vol. 28, Issue 3-4, pp. 345-51, (2015) (PubMed).

Bruin, Erener, Vela, Hu, Johnson, Kurata, Lynn, Piret, Asadi, Rezania, Kieffer: "Characterization of polyhormonal insulin-producing cells derived in vitro from human embryonic stem cells." in: Stem cell research, Vol. 12, Issue 1, pp. 194-208, (2014) (PubMed).

Karnik, Ludlow, Abuarab, Smith, Hardy, Elliott, Sivaprasadarao: "Endocytosis of HERG is clathrin-independent and involves arf6." in: PLoS ONE, Vol. 8, Issue 12, pp. e85630, (2014) (PubMed).

Li, Huang, Zhang, Kim, Yang, Kurata: "Decomposition of slide helix contributions to ATP-dependent inhibition of Kir6.2 channels." in: The Journal of biological chemistry, Vol. 288, Issue 32, pp. 23038-49, (2013) (PubMed).

Park, Ryu, Yu, Han, Ji, Oh, Sohn, Lim, Jeon, Lee, Lee, Lee, Berggren, Jeon, Ho: "Leptin promotes K(ATP) channel trafficking by AMPK signaling in pancreatic ?-cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 31, pp. 12673-8, (2013) (PubMed).

de Wet, Rees, Shimomura, Aittoniemi, Patch, Flanagan, Ellard, Hattersley, Sansom, Ashcroft: "Increased ATPase activity produced by mutations at arginine-1380 in nucleotide-binding domain 2 of ABCC8 causes neonatal diabetes." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 48, pp. 18988-92, (2007) (PubMed).

Aliases for ABCC8 抗体

ATP binding cassette subfamily C member 8 (ABCC8) 抗体
ATP-binding cassette, sub-family C (CFTR/MRP), member 8 (Abcc8) 抗体
ATP binding cassette subfamily C member 8 (Abcc8) 抗体
ABC36 抗体
D930031B21Rik 抗体
HHF1 抗体
HI 抗体
HRINS 抗体
MRP8 抗体
PHHI 抗体
SUR 抗体
Sur 抗体
SUR1 抗体
Sur1 抗体
SUR1delta2 抗体
TNDM2 抗体
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