ABCC2 抗体
(ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 2 (ABCC2))
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine\; therefore, this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia. [provided by RefSeq, Jul 2008].
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44 results
ABCC2
适用: 人, 小鼠, Cow, 犬, 兔, 猴
WB
宿主: 兔
Polyclonal
unconjugated
1 image
5 references
ABCC2
适用: 人, 小鼠, 大鼠
WB, ELISA, IF, ICC
宿主: 兔
Polyclonal
unconjugated
1 image
Latest Publications for our ABCC2 抗体
: "Stimulatory effect of CSE-generated H2S on hepatic mitochondrial biogenesis and the underlying mechanisms." in: Nitric oxide : biology and chemistry, Vol. 58, pp. 67-76, (2016) (PubMed).: "Expression in human endothelial cells of ADP-ribosylation factors, 20-kDa guanine nucleotide-binding proteins involved in the initiation of vesicular transport." in: Journal of molecular and cellular cardiology, Vol. 28, Issue 9, pp. 1911-20, (1997) (PubMed).
: "Isolation of a brefeldin A-inhibited guanine nucleotide-exchange protein for ADP ribosylation factor (ARF) 1 and ARF3 that contains a Sec7-like domain." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, Issue 23, pp. 12856-60, (1996) (PubMed).
: "Phospholipase D: a downstream effector of ARF in granulocytes." in: Science (New York, N.Y.), Vol. 263, Issue 5146, pp. 523-6, (1994) (PubMed).
: "ADP-ribosylation factors, 20,000 M(r) guanine nucleotide-binding protein activators of cholera toxin and components of intracellular vesicular transport systems." in: Cellular signalling, Vol. 5, Issue 4, pp. 367-79, (1993) (PubMed).
: "Purification of a protein cofactor required for ADP-ribosylation of the stimulatory regulatory component of adenylate cyclase by cholera toxin." in: The Journal of biological chemistry, Vol. 259, Issue 10, pp. 6228-34, (1984) (PubMed).
Aliases for ABCC2 抗体
ATP binding cassette subfamily C member 2 (ABCC2) 抗体ATP-binding cassette, sub-family C (CFTR/MRP), member 2 (Abcc2) 抗体
ATP binding cassette subfamily C member 2 (Abcc2) 抗体
ABC30 抗体
Abc30 抗体
AI173996 抗体
CMOAT 抗体
Cmoat 抗体
cMRP 抗体
DJS 抗体
MRP2 抗体
Mrp2 抗体
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