ABCC11 抗体
(ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 11 (ABCC11))
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This ABC full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. The product of this gene participates in physiological processes involving bile acids, conjugated steroids, and cyclic nucleotides. In addition, a SNP in this gene is responsible for determination of human earwax type. This gene and family member ABCC12 are determined to be derived by duplication and are both localized to chromosome 16q12.1. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008].
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31 results
ABCC11
适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 豚鼠, 马, Saccharomyces cerevisiae
WB
宿主: 兔
Polyclonal
unconjugated
1 image
Latest Publications for our ABCC11 抗体
: "Salinomycin overcomes ABC transporter-mediated multidrug and apoptosis resistance in human leukemia stem cell-like KG-1a cells." in: Biochemical and biophysical research communications, Vol. 394, Issue 4, pp. 1098-104, (2010) (PubMed).: "Human multidrug resistance protein 8 (MRP8/ABCC11), an apical efflux pump for steroid sulfates, is an axonal protein of the CNS and peripheral nervous system." in: Neuroscience, Vol. 137, Issue 4, pp. 1247-57, (2006) (PubMed).
Aliases for ABCC11 抗体
ATP binding cassette subfamily C member 11 (ABCC11) 抗体EWWD 抗体
MRP8 抗体
WW 抗体
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