ABCB1 蛋白
(ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1))
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| ABCB1 Protein (AA 620-709) (GST tag) | 人 | 小麦胚 |
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| ABCB1 Protein (AA 491-694) (His-IF2DI Tag) | 人 | 大肠杆菌（E. Coli） |
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| ABCB1 Protein (GST tag) | 人 | 大肠杆菌（E. Coli） |
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| ABCB1 Protein (AA 1-1280) (Strep Tag) | 人 | Cell-free protein synthesis (CFPS) |
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| ABCB1 Protein (AA 392-628) (His tag) | 人 | 大肠杆菌（E. Coli） |
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| ABCB1 Protein (His tag) | 人 | Insect cells (Sf9) |
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| ABCB1 Protein (DYKDDDDK Tag) | 人 | Insect cells (Sf9) |
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| ABCB1 Protein (AA 1-114) (His tag) | Entamoeba histolytica | 酵母菌 |
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| ABCB1 Protein (GST tag) | 人 | 大肠杆菌（E. Coli） |
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Protein
- AP (Affinity Purification: 所列应用)
- AA (Antibody Array: 所列应用)
- ELISA (ELISA: 所列应用)
- WB (Western Blotting: 所列应用)
1 reference - 宿主
- 人
- 宿主
- 小麦胚
- 蛋白类型
- Recombinant
Protein
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
Protein
- ELISA (ELISA: 所列应用)
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
Protein
- ELISA (ELISA: 所列应用)
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- 质量等级
- custom-made
- 宿主
- 人
- 宿主
- Cell-free protein synthesis (CFPS)
- 蛋白类型
- Recombinant
- 纯度
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Protein
- Imm (Immunogen: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
Protein
- WB (Western Blotting: 有验证图片)
- AbP (Antibody Production: 所列应用)
- STD (Standard: 所列应用)
- 宿主
- 人
- 宿主
- Insect cells (Sf9)
- 蛋白类型
- Recombinant
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
Protein
- WB (Western Blotting: 有验证图片)
- AbP (Antibody Production: 所列应用)
- STD (Standard: 所列应用)
- 宿主
- 人
- 宿主
- Insect cells (Sf9)
- 蛋白类型
- Recombinant
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
Protein
- ELISA (ELISA: 所列应用)
- 宿主
- Entamoeba histolytica
- 宿主
- 酵母菌
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Protein
- ELISA (ELISA: 所列应用)
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- Imm (Immunogen: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
Latest Publications for our ABCB1 蛋白
: "Quantitative atlas of membrane transporter proteins: development and application of a highly sensitive simultaneous LC/MS/MS method combined with novel in-silico peptide selection criteria." in: Pharmaceutical research, Vol. 25, Issue 6, pp. 1469-83, (2008) (PubMed).
Aliases for ABCB1 蛋白
ATP binding cassette subfamily B member 1 (ABCB1) 蛋白ATP binding cassette subfamily B member 1A (Abcb1a) 蛋白
ATP binding cassette subfamily B member 1 L homeolog (abcb1.L) 蛋白
ATP-binding cassette, sub-family B (MDR/TAP), member 1B (Abcb1b) 蛋白
ATP binding cassette subfamily B member 1 (Abcb1) 蛋白
ABC20 蛋白
Abcb1 蛋白
ABCB1 蛋白
CD243 蛋白
CLCS 蛋白
GP170 蛋白
mdr 蛋白
MDR1 蛋白
Mdr1 蛋白
Mdr1a 蛋白
Mdr1b 蛋白
P-GP 蛋白
p-gp 蛋白
PGP1 蛋白
Pgy-1 蛋白
PGY1 蛋白
Pgy1 蛋白
xemdr 蛋白
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