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ABCB1 蛋白

(ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1))
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. [provided by RefSeq, Jul 2008].
ABCB1 Protein (AA 620-709) (GST tag) ABCB1 Protein (AA 620-709) (GST tag) ABCB1 Protein (AA 620-709) (GST tag) (ABIN1305435)

ABCB1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA

ABCB1 Protein (AA 491-694) (His-IF2DI Tag) ABCB1 Protein (AA 491-694) (His-IF2DI Tag) ABCB1 Protein (AA 491-694) (His-IF2DI Tag) (ABIN7121929)

ABCB1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant Greater than 90 % by SDS-PAGE gel analyses ELISA, WB

ABCB1 Protein (AA 353-711) (His tag) ABCB1 Protein (AA 353-711) (His tag) ABCB1 Protein (AA 353-711) (His tag) (ABIN3083531)

Crystallography grade ABCB1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys

ABCB1 蛋白 by Grade

Find ABCB1 蛋白 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

ABCB1 蛋白 by Origin

Find ABCB1 蛋白 for a variety of species such as anti-Human ABCB1, anti-Entamoeba histolytica ABCB1. The species listed below are among those available. Click on a link to go to the corresponding products.

ABCB1 蛋白 by Source

Here you will find ABCB1 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

ABCB1 蛋白 by 蛋白类型

Here you can find ABCB1 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

ABCB1 蛋白 by 应用范围

Find ABCB1 蛋白 validated for a specific application such as ELISA, WB, SDS, Crys. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular ABCB1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1305435
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7121929
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3083531
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3083532
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3112158
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7505266
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Insect cells (Sf9)
Validations
  • (1)
Cat. No. ABIN2713530
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source Insect cells (Sf9)
Validations
  • (1)
Cat. No. ABIN2713531
Quantity 20 μg
Datasheet Datasheet
Reactivity Entamoeba histolytica
Source Yeast
Validations
Cat. No. ABIN7478939
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our ABCB1 蛋白

Kamiie, Ohtsuki, Iwase, Ohmine, Katsukura, Yanai, Sekine, Uchida, Ito, Terasaki: "Quantitative atlas of membrane transporter proteins: development and application of a highly sensitive simultaneous LC/MS/MS method combined with novel in-silico peptide selection criteria." in: Pharmaceutical research, Vol. 25, Issue 6, pp. 1469-83, (2008) (PubMed).

Aliases for ABCB1 蛋白

ATP binding cassette subfamily B member 1 (ABCB1) 蛋白
ATP binding cassette subfamily B member 1A (Abcb1a) 蛋白
ATP binding cassette subfamily B member 1 L homeolog (abcb1.L) 蛋白
ATP-binding cassette, sub-family B (MDR/TAP), member 1B (Abcb1b) 蛋白
ATP binding cassette subfamily B member 1 (Abcb1) 蛋白
ABC20 蛋白
Abcb1 蛋白
ABCB1 蛋白
CD243 蛋白
CLCS 蛋白
GP170 蛋白
mdr 蛋白
MDR1 蛋白
Mdr1 蛋白
Mdr1a 蛋白
Mdr1b 蛋白
P-GP 蛋白
p-gp 蛋白
PGP1 蛋白
Pgy-1 蛋白
PGY1 蛋白
Pgy1 蛋白
xemdr 蛋白
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