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ABCB1 蛋白

(ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1))
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. [provided by RefSeq, Jul 2008].

9 results

custom-made ABCB1 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
产品编号 ABIN7554517
 
ABCB1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Pubmed 1 reference
产品编号 ABIN1305435
 
ABCB1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant Greater than 90 % by SDS-PAGE gel analyses ELISA, WB
产品编号 ABIN7121929
 
ABCB1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7505266
 
ABCB1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant ELISA, WB, SDS
产品编号 ABIN7575669
 
custom-made ABCB1 宿主: 人 宿主: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS
产品编号 ABIN3112158
 
ABCB1 宿主: 人 宿主: Insect cells (Sf9) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2713531
 
ABCB1 宿主: 人 宿主: Insect cells (Sf9) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2713530
 
ABCB1 宿主: Entamoeba histolytica 宿主: 酵母菌 Recombinant > 90 % ELISA
产品编号 ABIN7478939
 
  • 类型 Protein
    • Protein
  • 应用范围
    • ELISA
    • Western Blotting (WB)
    • Antibody Production (AbP)
    • SDS-PAGE (SDS)
    • Standard (STD)
    • Affinity Purification (AP)
    • Antibody Array (AA)
  • 适用
    • Human
    • Entamoeba histolytica
  • 论文引用
  • 图像
  • Carrier free only
  • 抗体来源
    • Escherichia coli (E. coli)
    • Insect cells (Sf9)
    • Cell-free protein synthesis (CFPS)
    • HEK-293 Cells
    • Wheat germ
    • Yeast
  • 抗原表位
    • AA 1-1280
    • AA 1-114
    • AA 392-628
    • AA 491-694
    • AA 620-709
  • 标记
    • His tag
    • GST tag
    • DYKDDDDK Tag
    • His-IF2DI Tag
    • Strep Tag
  • 蛋白类型
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Grade
    • custom-made
  • Supplier
    • antibodies-online
    • OriGene
    • CUSABIO

Latest Publications for our ABCB1 蛋白

Kamiie, Ohtsuki, Iwase, Ohmine, Katsukura, Yanai, Sekine, Uchida, Ito, Terasaki: "Quantitative atlas of membrane transporter proteins: development and application of a highly sensitive simultaneous LC/MS/MS method combined with novel in-silico peptide selection criteria." in: Pharmaceutical research, Vol. 25, Issue 6, pp. 1469-83, (2008) (PubMed).

Aliases for ABCB1 蛋白

ATP binding cassette subfamily B member 1 (ABCB1) 蛋白
ATP binding cassette subfamily B member 1A (Abcb1a) 蛋白
ATP binding cassette subfamily B member 1 L homeolog (abcb1.L) 蛋白
ATP-binding cassette, sub-family B (MDR/TAP), member 1B (Abcb1b) 蛋白
ATP binding cassette subfamily B member 1 (Abcb1) 蛋白
ABC20 蛋白
Abcb1 蛋白
ABCB1 蛋白
CD243 蛋白
CLCS 蛋白
GP170 蛋白
mdr 蛋白
MDR1 蛋白
Mdr1 蛋白
Mdr1a 蛋白
Mdr1b 蛋白
P-GP 蛋白
p-gp 蛋白
PGP1 蛋白
Pgy-1 蛋白
PGY1 蛋白
Pgy1 蛋白
xemdr 蛋白
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