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ABCB1 蛋白

(ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1))

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. [provided by RefSeq, Jul 2008].

recommended

ABCB1 Protein (AA 1-1280) (His tag) (ABIN7554517)

custom-made ABCB1 宿主: 人宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

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recommended

ABCB1 Protein (AA 620-709) (GST tag) (ABIN1305435)

ABCB1 宿主: 人宿主: 小麦胚 Recombinant ELISA, WB, AP, AA

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recommended

ABCB1 Protein (AA 491-694) (His-IF2DI Tag) (ABIN7121929)

ABCB1 宿主: 人宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % by SDS-PAGE gel analyses ELISA, WB

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ABCB1 蛋白 by Grade

Find ABCB1 蛋白 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

ABCB1 蛋白 by Origin

Find ABCB1 蛋白 for a variety of species such as anti-Human ABCB1, anti-Entamoeba histolytica ABCB1. The species listed below are among those available. Click on a link to go to the corresponding products.

ABCB1 蛋白 by Source

Here you will find ABCB1 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

ABCB1 蛋白 by 蛋白类型

Here you can find ABCB1 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

ABCB1 蛋白 by 应用范围

Find ABCB1 蛋白 validated for a specific application such as ELISA, WB, AbP, STD. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular ABCB1 蛋白

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

ABCB1 Protein (AA 1-1280) (His tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN7554517

Quantity 1 mg

Datasheet Datasheet

ABCB1 Protein (AA 620-709) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1305435

Quantity 10 μg

Datasheet Datasheet

ABCB1 Protein (AA 491-694) (His-IF2DI Tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7121929

Quantity 50 μg

Datasheet Datasheet

ABCB1 Protein (AA 392-628) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7505266

Quantity 100 μg

Datasheet Datasheet

ABCB1 Protein (GST tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7575669

Quantity 100 μg

Datasheet Datasheet

ABCB1 Protein (DYKDDDDK Tag)

Reactivity Human

Source Insect cells (Sf9)

Validations

Cat. No. ABIN2713531

Quantity 20 μg

Datasheet Datasheet

ABCB1 Protein (His tag)

Reactivity Human

Source Insect cells (Sf9)

Validations

Cat. No. ABIN2713530

Quantity 20 μg

Datasheet Datasheet

ABCB1 Protein (AA 1-114) (His tag)

Reactivity Entamoeba histolytica

Source Yeast

Validations

Cat. No. ABIN7478939

Quantity 100 μg

Datasheet Datasheet

Latest Publications for our ABCB1 蛋白

Kamiie, Ohtsuki, Iwase, Ohmine, Katsukura, Yanai, Sekine, Uchida, Ito, Terasaki: "Quantitative atlas of membrane transporter proteins: development and application of a highly sensitive simultaneous LC/MS/MS method combined with novel in-silico peptide selection criteria." in: Pharmaceutical research, Vol. 25, Issue 6, pp. 1469-83, (2008) (PubMed).

Aliases for ABCB1 蛋白

ATP binding cassette subfamily B member 1 (ABCB1) 蛋白
ATP binding cassette subfamily B member 1A (Abcb1a) 蛋白
ATP binding cassette subfamily B member 1 L homeolog (abcb1.L) 蛋白
ATP-binding cassette, sub-family B (MDR/TAP), member 1B (Abcb1b) 蛋白
ATP binding cassette subfamily B member 1 (Abcb1) 蛋白
ABC20 蛋白
Abcb1 蛋白
ABCB1 蛋白
CD243 蛋白
CLCS 蛋白
GP170 蛋白
mdr 蛋白
MDR1 蛋白
Mdr1 蛋白
Mdr1a 蛋白
Mdr1b 蛋白
P-GP 蛋白
p-gp 蛋白
PGP1 蛋白
Pgy-1 蛋白
PGY1 蛋白
Pgy1 蛋白
xemdr 蛋白

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ABCB1 蛋白 by Grade

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Popular ABCB1 蛋白

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Aliases for ABCB1 蛋白

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