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AAK1 产品

(AP2 associated kinase 1 (AAK1))

Categories

Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. This gene encodes a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008].

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Featured AAK1 Categories

AAK1 抗体

High quality antibodies with extensive validation data.

AAK1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

AAK1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended AAK1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (4)
Cat. No. ABIN524804
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7144390
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IHC (p)
Validations
  • (3)
Cat. No. ABIN462517
Quantity 0.05 mg
Datasheet Datasheet

Recommended AAK1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6964516
Quantity 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN5648154
Quantity 96 tests
Datasheet Datasheet
Reactivity Cow
Analytical Method
Validations
Cat. No. ABIN1122169
Quantity 96 tests
Datasheet Datasheet

Recommended AAK1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1305395
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1305397
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3087952
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our AAK1 Products

Henderson, Conner: "A novel AAK1 splice variant functions at multiple steps of the endocytic pathway." in: Molecular biology of the cell, Vol. 18, Issue 7, pp. 2698-706, (2007) (PubMed).

Aoudjit, Vuori: "Integrin signaling inhibits paclitaxel-induced apoptosis in breast cancer cells." in: Oncogene, Vol. 20, Issue 36, pp. 4995-5004, (2001) (PubMed).

Rytömaa, Lehmann, Downward: "Matrix detachment induces caspase-dependent cytochrome c release from mitochondria: inhibition by PKB/Akt but not Raf signalling." in: Oncogene, Vol. 19, Issue 39, pp. 4461-8, (2000) (PubMed).

Synonyms and alternative names related to AAK1

AP2 associated kinase 1 (AAK1), AP2 associated kinase 1 (Aak1), uncharacterized protein FLJ45252 (LOC100512341), AP2 associated kinase 1b (aak1b), 5530400K14Rik, 9630042K20, aak1, AU067724, AU067726, BC028270, C79663, D6Ertd245e, mKIAA1048, R75501, RGD1563580, si:dkey-261l11.5

Protein level used designations for AAK1

  • AP2-associated protein kinase 1
  • adaptor-associated kinase 1
  • AP2 associated kinase 1
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