anti-TCF7 (TCF7) 抗体产品概述

Full name:
anti-Transcription Factor 7 (T-Cell Specific, HMG-Box) 抗体 (TCF7)
在www.antibodies-online.cn可供110 Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7) 抗体的20不同的供货商。 再加上,我们可以发TCF7 蛋白 (4)TCF7 试剂盒 (1)和数多这个蛋白质的别的产品。 总共126 TCF7产品已列进来了。
别名:
AI465550, TCF-1, Tcf1

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引用最多的anti-TCF7 抗体

  1. Human Polyclonal TCF7 Primary Antibody for EIA, WB - ABIN357291 : Smit, Baas, Kuipers, Korswagen, van de Wetering, Clevers: Wnt activates the Tak1/Nemo-like kinase pathway. in The Journal of biological chemistry 2004 (PubMed)
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  2. Human Polyclonal TCF7 Primary Antibody for ELISA, WB - ABIN1533714 : Roose, Huls, van Beest, Moerer, van der Horn, Goldschmeding, Logtenberg, Clevers: Synergy between tumor suppressor APC and the beta-catenin-Tcf4 target Tcf1. in Science (New York, N.Y.) 1999 (PubMed)

  3. Human Polyclonal TCF7 Primary Antibody for WB - ABIN2777292 : Willinger, Freeman, Herbert, Hasegawa, McMichael, Callan: Human naive CD8 T cells down-regulate expression of the WNT pathway transcription factors lymphoid enhancer binding factor 1 and transcription factor 7 (T cell factor-1) following antigen encounter in vitro and in vivo. in Journal of immunology (Baltimore, Md. : 1950) 2006 (PubMed)

更多抗TCF7的相互作用对抗体

Human Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7) interaction partners

  1. High expression of TCF7 is associated with osteosarcoma.

  2. Findings indicate that breast cancer cells with a hyperactive AF1q (显示 MLLT11 抗体)/TCF7/CD44 (显示 CD44 抗体) regulatory axis in the primary sites may represent "metastatic founder cells" which have invasive properties.

  3. TCF7 plays critical roles in lung diseases [review]

  4. Tcf7 levels are lower in islets taken from patients with type 2 diabetes. Knockdown of TCF7 in islets impairs the cytoprotective respo (显示 GIP 抗体)nsiveness to GIP and enhances the magnitude of apoptotic injury.

  5. Capsaicin-induced apoptosis in pancreatic cancer cells was associated with inhibition of beta-catenin (显示 CTNNB1 抗体) signaling due to the dissociation of beta-catenin (显示 CTNNB1 抗体)/TCF-1 (显示 HNF1A 抗体) complex and the process was orchestrated by STAT-3 (显示 STAT3 抗体).

  6. we show that TCF7 is a direct target of miR (显示 MLXIP 抗体)-34a in prostate cancer that has metastasized to the bone

  7. induction of expression activates the Wnt (显示 WNT2 抗体) signaling pathway, leading to priming of liver cancer stem cells self-renewal and tumor propagation

  8. RUNX2 (显示 RUNX2 抗体) signaling pathways with their partners TCF7 and FGFR1 (显示 FGFR1 抗体)/2 may not be involved in CCD (显示 RUNX2 抗体) pathogenesis

  9. Results suggest ivermectin as therapeutic WNT protein-TCF (显示 HNF4A 抗体) transcription factor pathway response blocker to treat WNT (显示 WNT2 抗体)-TCF (显示 HNF4A 抗体)-dependent diseases including multiple cancers.

  10. miRNAs inhibited the expression of the luciferase reporter constructs containing 3'UTRs of these genes and downregulated protein expression of TERT (显示 TERT 抗体) and the TCF7 transcription factor, which mediates the canonical Wnt (显示 WNT2 抗体) pathway.

Mouse (Murine) Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7) interaction partners

  1. Tcf7 levels are lower in islets taken from diabetic mice. Knockdown of TCF7 in islets impairs the cytoprotective responsiveness to GIP (显示 GIP 抗体) and enhances the magnitude of apoptotic injury.

  2. TCF-1-deficient CD4+ CD8+ double positive thymocytes fail to undergo TCR alpha Valpha14-Jalpha18 rearrangement and produce significantly fewer Natural killer T cells.

  3. The data suggest that miR (显示 MLXIP 抗体)-24 participates in osteogenic differentiation by targeting and regulating Tcf-1 (显示 HNF1A 抗体) expression in osteoblastic cells.

  4. this study proposes a regulatory role for TCF7 in limiting access to the Treg lineage

  5. Our results support a critical role for miR (显示 MLXIP 抗体)-22-3p and its target, Tcf7, in the pathogenesis of diabetes by upregulating gluconeogenesis.

  6. TCF-1 (显示 HNF1A 抗体) was essential for both the initiation of T(FH) differentiation and the effector function of differentiated T(FH) cells during acute viral infection. TCF-1 (显示 HNF1A 抗体) promoted Bcl-6 (显示 BCL6 抗体) expression but repressed Blimp1 (显示 PRDM1 抗体) expression.

  7. Chromatin immunoprecipitation sequencing revealed the transcription factor Tcf7 and the chemokine receptor (显示 CCR1 抗体) Ccr7 (显示 CCR7 抗体) as Foxo1 (显示 FOXO1 抗体)-bound target genes, which have critical functions in central-memory T cell differentiation and trafficking.

  8. Our data support that the loss of Tcf7 diminishes hematopoietic stem cell function.

  9. TCF-1 (显示 HNF1A 抗体) mediates repression of Notch (显示 NOTCH1 抗体) pathway in T lineage-committed early thymocytes.

  10. These results are reminiscent of the critical roles of TCF-1 (显示 HNF1A 抗体) in early T cell development.

TCF7 抗原简介

Antigen Summary

The protein encoded by this gene is a transcriptional activator that plays an important role in lymphocyte differentiation. This gene is expressed predominantly in T-cells. The encoded protein can bind an enhancer element and activate the CD3E gene, and it also may repress the CTNNB1 and TCF7L2 genes through a feedback mechanism. Several transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with TCF7

  • transcription factor 7 (T-cell specific, HMG-box) (TCF7) 抗体
  • transcription factor 7 (T-cell specific, HMG-box) (Tcf7) 抗体
  • transcription factor 7, T cell specific (Tcf7) 抗体
  • AI465550 抗体
  • TCF-1 抗体
  • Tcf1 抗体

Protein level used designations for TCF7

T-cell-specific transcription factor 1 , transcription factor 7 , transcription factor 7, T-cell specific , T cell factor-1 , T-cell factor 1 , TCF-7

GENE ID SPECIES
6932 Homo sapiens
481506 Canis lupus familiaris
782690 Bos taurus
363595 Rattus norvegicus
21414 Mus musculus
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