Use your antibodies-online credentials, if available.
Select your species
Our study provides insights into the mechanism of TAB3 regulating activity and suggests its important implications in triple negative breast cancer metastasis.
Data show that knockdown of transforming growth factor-activated kinase 1 (TAK1)-binding protein 3 (TAB3) inhibited proliferation of non-small cell lung cancer (NSCLC) cells.
TAB3 regulated ovarian cancer cell bioactivity and chemotherapy performance via the NF-kappaB (显示 NFKB1 ELISA试剂盒) pathway.
Upregulation of miR (显示 MLXIP ELISA试剂盒)-532-5p and subsequent suppression of the SESTD1 and TAB3 genes represent an antiviral response aimed at limiting West Nile virus infection.
miR (显示 MLXIP ELISA试剂盒)-30a in MSCs may participate in the immune dysregulation of the maternal-fetal interface during PE
miR (显示 MLXIP ELISA试剂盒)-26b suppresses NF-kappaB (显示 NFKB1 ELISA试剂盒) signaling and sensitizes hepatocellular carcinoma cells to doxorubicin-induced apoptosis by inhibiting the expression of TAK1 (显示 MAP3K7 ELISA试剂盒) and TAB3.
conclude that TRIM38 (显示 TRIM38 ELISA试剂盒) negatively regulates TNFalpha (显示 TNF ELISA试剂盒)- and IL-1beta (显示 IL1B ELISA试剂盒)-induced signaling by mediating lysosome-dependent degradation of TAB2 (显示 TAB2 ELISA试剂盒)/3, two critical components in TNFalpha (显示 TNF ELISA试剂盒)- and IL-1beta (显示 IL1B ELISA试剂盒)-induced signaling pathways
Studies show that three proteins expressed in HEK (显示 EPHA3 ELISA试剂盒)-293T cells (NAP1 (显示 IL8 ELISA试剂盒), TANK and TBKBP1 (显示 TBKBP1 ELISA试剂盒)) interact with TBK1 (显示 TBK1 ELISA试剂盒).
MiR (显示 MLXIP ELISA试剂盒)-23b suppresses IL-17 (显示 IL17A ELISA试剂盒)-, tumor necrosis factor alpha (TNF-alpha (显示 TNF ELISA试剂盒))- or IL-1beta (显示 IL1B ELISA试剂盒)-induced NF-kappaB (显示 NFKB1 ELISA试剂盒) activation and inflammatory cytokine expression by targeting TAB2 (显示 TAB2 ELISA试剂盒), TAB3 and IKK-alpha (显示 CHUK ELISA试剂盒).
human TAB2 (显示 TAB2 ELISA试剂盒) and TAB3, ubiquitin-chain sensory proteins involved in NF-kappaB (显示 NFKB1 ELISA试剂盒) signalling, are directly inactivated by enteropathogenic Escherichia coli NleE, a conserved bacterial type-III-secreted effector responsible for blocking host NF-kappaB (显示 NFKB1 ELISA试剂盒) signalling
Findings indicate that the absence of TAB3 plays a harmful role in ischemic heart disease
TAB2 (显示 TAB2 ELISA试剂盒) and TAB3 are essential for B cell activation (显示 BLNK ELISA试剂盒) leading to antigen-specific antibody responses, as well as B-1 and marginal zone B cell development.
The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
TGF-beta activated kinase 1/MAP3K7 binding protein 3
, mitogen-activated protein kinase kinase kinase 7-interacting protein 3-like
, NF-kappa-B-activating protein 1
, NFkB activating protein 1
, TAK1-binding protein 3
, TGF-beta-activated kinase 1 and MAP3K7-binding protein 3
, TGF-beta-activated kinase 1-binding protein 3
, mitogen-activated protein kinase kinase kinase 7 interacting protein 3
, mitogen activated protein kinase kinase kinase 7 interacting protein 3
, mitogen-activated protein kinase kinase kinase 7-interacting protein 3