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抗Human PKC delta 抗体:
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抗Rat (Rattus) PKC delta 抗体:
Human Monoclonal PKC delta Primary Antibody for IF, IP - ABIN967942
Bell, Burns: Lipid activation of protein kinase C. in The Journal of biological chemistry 1991
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Human Monoclonal PKC delta Primary Antibody for IF, IP - ABIN967943
Blass, Kronfeld, Kazimirsky, Blumberg, Brodie: Tyrosine phosphorylation of protein kinase Cdelta is essential for its apoptotic effect in response to etoposide. in Molecular and cellular biology 2001
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Human Polyclonal PKC delta Primary Antibody for IHC - ABIN966838
Sakamoto, Aschenbach, Hirshman, Goodyear: Akt signaling in skeletal muscle: regulation by exercise and passive stretch. in American journal of physiology. Endocrinology and metabolism 2003
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Human PKC delta Primary Antibody for IHC - ABIN966837
Zhang, Keane, Zhu, Sharma, Rozengurt, Strieter, Dubinett, Huang: Interleukin-7 and transforming growth factor-beta play counter-regulatory roles in protein kinase C-delta-dependent control of fibroblast collagen synthesis in pulmonary fibrosis. in The Journal of biological chemistry 2004
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Human Polyclonal PKC delta Primary Antibody for WB - ABIN2802039
Aris, Basta, Holmes, Ballas, Moomaw, Rankl, Blobel, Loomis, Burns: Molecular and biochemical characterization of a recombinant human PKC-delta family member. in Biochimica et biophysica acta 1993
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Human Polyclonal PKC delta Primary Antibody for IHC, WB - ABIN362384
Van Kolen, Slegers: Atypical PKCzeta is involved in RhoA-dependent mitogenic signaling by the P2Y(12) receptor in C6 cells. in The FEBS journal 2006
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Human Monoclonal PKC delta Primary Antibody for IF, ELISA - ABIN562385
Chen, Nguyen, Shively: Role of calpain-9 and PKC-delta in the apoptotic mechanism of lumen formation in CEACAM1 transfected breast epithelial cells. in Experimental cell research 2010
ADP inhibits mesothelioma cell proliferation via PKC-delta/JNK (显示 MAPK8 抗体)/p21 (显示 CDKN1A 抗体)/p27 (显示 PAK2 抗体) signaling.
PKCdelta, via MAPK (显示 MAPK1 抗体) pathway, is involved in the glycodelin (显示 PAEP 抗体)-driven cell differentiation.
PKCdelta is a critical regulator of signaling mechanisms of neutrophil-endothelium interaction in acute inflammation. Inhibition of PKCdelta in human endothelial cells and neutrophils reduced chemoattractant-induced neutrophil migration across TNF-alpha (显示 TNF 抗体)-activated endothelium, and reduced expression of E-selectin (显示 SELE 抗体) and ICAM-1 (显示 ICAM1 抗体). Shear rate and vascular geometry regulate the impact of PKCdelta inhibition of neutrophil-endot...
Lysophosphatidylcholines prime polymorphonuclear neutrophil through Hck (显示 HCK 抗体)-dependent activation of PKCdelta, which stimulates PKCgamma (显示 PRKCG 抗体), resulting in translocation of phosphorylated p47(phox).
The interplay between intracellular progesterone receptor (显示 PGR 抗体) and PRKCA (显示 PKCa 抗体)-PRKCD plays a key role in migration and invasion of human glioblastoma cells.
Amphiregulin (显示 AREG 抗体) enhances VEGF-A (显示 VEGFA 抗体) production in human chondrosarcoma cells and promotes angiogenesis by inhibiting miR (显示 MLXIP 抗体)-206 via FAK (显示 PTK2 抗体)/c-Src (显示 SRC 抗体)/PKCdelta pathway.
In the present investigation, we demonstrated that miR486 is negatively associated with the expression of PKC-delta and could regulate the development of osteosarcoma. miR (显示 MLXIP 抗体)-486 may be a potential target for the treatment of osteosarcoma
PKCdelta and PKCepsilon (显示 PRKCE 抗体) work as a functional couple with opposite roles on thrombopoiesis, and the modulation of their balance strongly impacts platelet production.
These findings suggest that targeting Wnt (显示 WNT2 抗体)/beta-catenin (显示 CTNNB1 抗体) or Akt (显示 AKT1 抗体) pathways may increase the efficacy of taxane chemotherapy in advanced human prostate cancers that have lost PKCdelta expression.
description of a rare monogenic form of juvenile systemic lupus erythematosus caused by a novel but damaging homozygous mutation affecting the active region of PRKCD.
HIF1a (显示 HIF1A 抗体) transcriptional activity is stimulated by Protein kinase A-dependent phosphorylation
Generation of the Dnajb1 (显示 DNAJB1 抗体)-Prkaca (显示 PRKACA 抗体) fusion gene in wild-type mice to be sufficient to initiate formation of tumors that have many features of human fibrolamellar hepatocellular carcinonma.
Data indicate a subpopulation of the CaV1.2 (显示 CACNA1C 抗体) channel pore-forming subunit (alpha1C) within nanometer proximity of protein kinase A (PKA) at the sarcolemma of murine and human arterial myocytes.
S1928A KI mice failed to induce long-term potentiation in response to prolonged theta-tetanus (PTT-LTP (显示 SCP2 抗体)), a form of synaptic plasticity that requires Cav1.2 (显示 CACNA1C 抗体) and enhancement of its activity by the beta2-adrenergic receptor (显示 ADRB2 抗体) (beta2AR (显示 ADRB2 抗体))-cAMP-PKA cascade.
Data show that laminin alpha2beta1gamma1 (Lm211) can inhibit neuregulin 1 (显示 NRG1 抗体) type III (Nrg1III) by limiting protein kinase A (PKA) activation, which is required to initiate myelination.
spinal PKCdelta has a role in the development of chronic pain in SCD (显示 SCD 抗体), which may become a potential target for pharmacological interventions
study identifies a new role of Dual-AKAP1 (显示 AKAP1 抗体) in regulating mitochondrial trafficking through Miro-2 (显示 RHOT2 抗体), and supports a model in which PINK1 (显示 PINK1 抗体) and mitochondrial PKA participate in a similar neuroprotective signaling pathway to maintain dendrite connectivity
Data suggest that enzyme activation by cAMP involves highly stable conformation of Prkar1a as it binds to Prkaca; glycine residue, G235, appears to function as hinge in B/C helix conserved in Prkar1a; this "Flipback" conformation plays role in cAMP association to A domain of Prkar1a. (Prkar1a = cyclic AMP-dependent protein kinase RIalpha subunit; Prkaca = cyclic AMP-dependent protein kinase catalytic subunit)
K8/K18 (显示 KRT18 抗体)-dependent PKCdelta- and ASMase (显示 SMPD1 抗体)-mediated modulation of lipid raft size can explain the more prominent FasR-mediated signaling resulting from K8/K18 (显示 KRT18 抗体) loss.
MALAT1 recruits splice factor serine-arginine-rich splice factor 2 (SRSF2 (显示 SRSF2 抗体)) to promote alternative splicing of PKCdeltaII.
Report PRKCD-dependent regulation of bovine embryonic development, gene expression and post-hatching events.
investigation of signaling mechanism used by fibroblast growth factor-2 (FGF2 (显示 FGF2 抗体)) to regulate interferon-tau (IFNT) production in trophoblasts: several lines of evidence suggest that FGF2 (显示 FGF2 抗体) regulates IFNT production in trophoblasts by acting through PRKCD
deltaPKC inhibition or varepsilonPKC activation repairs endothelial vascular dysfunction by regulating eNOS (显示 NOS3 抗体) post-translational modification
stimulation of bovine theca cells with lysophosphatidic acid leads to redistribution of protein kinase C delta from the cytosol to the perinuclear area and in the presence of LH, complete nuclear translocation of protein kinase C delta is induced
Protein kinase (显示 CDK7 抗体) Cdelta-dependent phosphorylation of syndecan-4 (显示 SDC4 抗体) regulates cell migration.
Activation of PKC (显示 PKC 抗体) induces the translocation of Nrf2 (显示 NFE2L2 抗体) and the enhancement of endogenous antioxidant defenses in ischemic preconditioned rabbit heart.
PKC-delta (显示 PRKCG 抗体) mediates the apoptotic processes through ROS (显示 ROS1 抗体)-dependent caspase-3 (显示 CASP3 抗体) activation
Here, substitution studies on peptides correlating to the C1B domain in PKC gamma (显示 PRKCG 抗体) show that a flexible structure and ability to be phosphorylated on serine 109 are critical for this purpose.
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. Studies both in human and mice demonstrate that this kinase is involved in B cell signaling and in the regulation of growth, apoptosis, and differentiation of a variety of cell types. Alternatively spliced transcript variants encoding the same protein have been observed.
protein kinase C delta VIII
, protein kinase C delta type
, tyrosine-protein kinase PRKCD
, protein kinase C delta variant IX
, protein kinase C, delta IV
, protein kinase C, delta V
, protein kinase C[d]
, protein kinase-delta2
, protein kinase C, delta
, protein kinase C delta type-like
, PKA C-alpha
, cAMP-dependent protein kinase catalytic subunit alpha
, sperm cAMP-dependent protein kinase catalytic subunit
, protein kinase C delta
, protein kinase C gamma type