anti-PKC delta (PKCd) 抗体产品概述

Full name:
anti-Protein Kinase C, delta 抗体 (PKCd)
在www.antibodies-online.cn可供293 Protein Kinase C, delta (PKCd) 抗体的28不同的供货商。 再加上,我们可以发PKC delta 试剂盒 (49)PKC delta 蛋白 (25)和数多这个蛋白质的别的产品。 总共384 PKC delta产品已列进来了。
别名:
AI385711, D14Ertd420e, fb09d10, fv43b11, MAY1, nPKC-delta, Pkaca, PKC-delta, pkc-delta2, Pkcd, PKCdelta, PKC[d], PRKCD, tpa-1, wu:fb09d10, wu:fv43b11, zgc:56558

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引用最多的anti-PKC delta 抗体

  1. Human Monoclonal PKC delta Primary Antibody for IF, IP - ABIN967942 : Bell, Burns: Lipid activation of protein kinase C. in The Journal of biological chemistry 1991 (PubMed)
    Show all 5 references for 967942

  2. Human Polyclonal PKC delta Primary Antibody for IF, IHC (p) - ABIN197564 : Zhang, Keane, Zhu, Sharma, Rozengurt, Strieter, Dubinett, Huang: Interleukin-7 and transforming growth factor-beta play counter-regulatory roles in protein kinase C-delta-dependent control of fibroblast collagen synthesis in pulmonary fibrosis. in The Journal of biological chemistry 2004 (PubMed)
    Show all 4 references for 197564

  3. Human Polyclonal PKC delta Primary Antibody for IHC (p), WB - ABIN197068 : Van Kolen, Slegers: Atypical PKCzeta is involved in RhoA-dependent mitogenic signaling by the P2Y(12) receptor in C6 cells. in The FEBS journal 2006 (PubMed)
    Show all 2 references for 197068

  4. Human Polyclonal PKC delta Primary Antibody for IF, ELISA - ABIN1532521 : Mitchell, Barker, Martindale, Kamalati, Lowe, Page, Gusterson, Crompton: Cloning and characterisation of cDNAs encoding a novel non-receptor tyrosine kinase, brk, expressed in human breast tumours. in Oncogene 1994 (PubMed)

  5. Human Polyclonal PKC delta Primary Antibody for IHC, ELISA - ABIN1531464 : Benes, Wu, Elia, Dharia, Cantley, Soltoff: The C2 domain of PKCdelta is a phosphotyrosine binding domain. in Cell 2005 (PubMed)

更多抗PKC delta的相互作用对抗体

Human Protein Kinase C, delta (PKCd) interaction partners

  1. PKCdelta is a critical regulator of signaling mechanisms of neutrophil-endothelium interaction in acute inflammation. Inhibition of PKCdelta in human endothelial cells and neutrophils reduced chemoattractant-induced neutrophil migration across TNF-alpha (显示 TNF 抗体)-activated endothelium, and reduced expression of E-selectin (显示 SELE 抗体) and ICAM-1 (显示 ICAM1 抗体). Shear rate and vascular geometry regulate the impact of PKCdelta inhibition of neutrophil-endot...

  2. Lysophosphatidylcholines prime polymorphonuclear neutrophil through Hck (显示 HCK 抗体)-dependent activation of PKCdelta, which stimulates PKCgamma (显示 PRKCG 抗体), resulting in translocation of phosphorylated p47(phox).

  3. The interplay between intracellular progesterone receptor (显示 PGR 抗体) and PRKCA (显示 PKCa 抗体)-PRKCD plays a key role in migration and invasion of human glioblastoma cells.

  4. Amphiregulin (显示 AREG 抗体) enhances VEGF-A (显示 VEGFA 抗体) production in human chondrosarcoma cells and promotes angiogenesis by inhibiting miR (显示 MLXIP 抗体)-206 via FAK (显示 PTK2 抗体)/c-Src (显示 SRC 抗体)/PKCdelta pathway.

  5. In the present investigation, we demonstrated that miR486 is negatively associated with the expression of PKC-delta and could regulate the development of osteosarcoma. miR (显示 MLXIP 抗体)-486 may be a potential target for the treatment of osteosarcoma

  6. PKCdelta and PKCepsilon (显示 PRKCE 抗体) work as a functional couple with opposite roles on thrombopoiesis, and the modulation of their balance strongly impacts platelet production.

  7. These findings suggest that targeting Wnt (显示 WNT2 抗体)/beta-catenin (显示 CTNNB1 抗体) or Akt (显示 AKT1 抗体) pathways may increase the efficacy of taxane chemotherapy in advanced human prostate cancers that have lost PKCdelta expression.

  8. description of a rare monogenic form of juvenile systemic lupus erythematosus caused by a novel but damaging homozygous mutation affecting the active region of PRKCD.

  9. MALAT1 recruits splice factor serine-arginine-rich splice factor 2 (SRSF2 (显示 SRSF2 抗体)) to promote alternative splicing of PKCdeltaII.

  10. mechanistic studies, inhibition of SRC (显示 SRC 抗体) and PKCdelta completely ablated the ability of MDA-7/IL-24 (显示 IL24 抗体) to reduce the Bcl-x(L (显示 BCL2L1 抗体))/(s) mRNA ratio and cell viability. These findings show that Bcl-x (显示 BCL2L1 抗体)(s) expression is an important mediator of MDA-7/IL-24 (显示 IL24 抗体)-induced cytotoxicity requiring the SRC (显示 SRC 抗体)/PKCdelta signaling axis in NSCLC cells.

Mouse (Murine) Protein Kinase C, delta (PKCd) interaction partners

  1. study identifies a new role of Dual-AKAP1 (显示 AKAP1 抗体) in regulating mitochondrial trafficking through Miro-2 (显示 RHOT2 抗体), and supports a model in which PINK1 (显示 PINK1 抗体) and mitochondrial PKA participate in a similar neuroprotective signaling pathway to maintain dendrite connectivity

  2. Data suggest that enzyme activation by cAMP involves highly stable conformation of Prkar1a as it binds to Prkaca; glycine residue, G235, appears to function as hinge in B/C helix conserved in Prkar1a; this "Flipback" conformation plays role in cAMP association to A domain of Prkar1a. (Prkar1a = cyclic AMP-dependent protein kinase RIalpha subunit; Prkaca = cyclic AMP-dependent protein kinase catalytic subunit)

  3. K8/K18 (显示 KRT18 抗体)-dependent PKCdelta- and ASMase (显示 SMPD1 抗体)-mediated modulation of lipid raft size can explain the more prominent FasR-mediated signaling resulting from K8/K18 (显示 KRT18 抗体) loss.

  4. MALAT1 recruits splice factor serine-arginine-rich splice factor 2 (SRSF2 (显示 SRSF2 抗体)) to promote alternative splicing of PKCdeltaII.

  5. cAMP dependent protein kinase A (PKA) is a key intracellular factor mediating SHH (显示 SHH 抗体) signaling through regulation of GLI3 (显示 GLI3 抗体) processing.

  6. this study shows illustrates for the first time the ability of protein kinase A to increase colony-stimulating factor 1 receptor (显示 CSF1R 抗体) DNA methylation (显示 HELLS 抗体) resulting in macrophage maturation

  7. these results suggest that the activation of 5-HT1D receptors selectively enhanced IA via the Gbetagamma of the Go-protein, PKA, and the sequential B-Raf (显示 SNRPE 抗体)-dependent p38 MAPK (显示 MAPK14 抗体) signaling cascade.

  8. SphK1 (显示 SPHK1 抗体) dependent PKC-delta activation plays an important role in promoting NF-kappaB (显示 NFKB1 抗体) activation and inflammatory response in acute liver failure, and inhibition of PKC-delta activation might be a potential therapeutic strategy for this disease.

  9. PKCdelta activity exerts a dual role through the autophagy mechanism, decreasing proliferative capacity of mammary tumor cells but also regulating tumor stem cell self-renewal.

  10. alpha(1)-AR activation is anti-apoptotic and protective during cardiac ischemia due to glucose deprivation and not hypoxia by enhancing glucose uptake into the heart via PKCdelta-mediated GLUT (显示 SLC1A3 抗体) translocation that may be specific to the alpha(1A)-AR subtype.

Cow (Bovine) Protein Kinase C, delta (PKCd) interaction partners

  1. Report PRKCD-dependent regulation of bovine embryonic development, gene expression and post-hatching events.

  2. investigation of signaling mechanism used by fibroblast growth factor-2 (FGF2 (显示 FGF2 抗体)) to regulate interferon-tau (IFNT) production in trophoblasts: several lines of evidence suggest that FGF2 (显示 FGF2 抗体) regulates IFNT production in trophoblasts by acting through PRKCD

  3. deltaPKC inhibition or varepsilonPKC activation repairs endothelial vascular dysfunction by regulating eNOS (显示 NOS3 抗体) post-translational modification

  4. stimulation of bovine theca cells with lysophosphatidic acid leads to redistribution of protein kinase C delta from the cytosol to the perinuclear area and in the presence of LH, complete nuclear translocation of protein kinase C delta is induced

  5. Protein kinase (显示 CDK7 抗体) Cdelta-dependent phosphorylation of syndecan-4 (显示 SDC4 抗体) regulates cell migration.

Rabbit Protein Kinase C, delta (PKCd) interaction partners

  1. Activation of PKC (显示 PKC 抗体) induces the translocation of Nrf2 (显示 NFE2L2 抗体) and the enhancement of endogenous antioxidant defenses in ischemic preconditioned rabbit heart.

  2. PKC-delta (显示 PRKCG 抗体) mediates the apoptotic processes through ROS (显示 ROS1 抗体)-dependent caspase-3 (显示 CASP3 抗体) activation

PKC delta (PKCd) 抗原简介

Antigen Summary

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. Studies both in human and mice demonstrate that this kinase is involved in B cell signaling and in the regulation of growth, apoptosis, and differentiation of a variety of cell types. Alternatively spliced transcript variants encoding the same protein have been observed.

Alternative names and synonyms associated with PKC delta (PKCd)

  • protein kinase C, delta a (prkcda) 抗体
  • protein kinase C, delta (prkcd-b) 抗体
  • protein kinase C, delta (prkcd) 抗体
  • protein kinase C, delta (LOC100230711) 抗体
  • protein kinase C, delta (PRKCD) 抗体
  • protein kinase C, delta (Prkcd) 抗体
  • protein kinase, cAMP dependent, catalytic, alpha (Prkaca) 抗体
  • AI385711 抗体
  • D14Ertd420e 抗体
  • fb09d10 抗体
  • fv43b11 抗体
  • MAY1 抗体
  • nPKC-delta 抗体
  • Pkaca 抗体
  • PKC-delta 抗体
  • pkc-delta2 抗体
  • Pkcd 抗体
  • PKCdelta 抗体
  • PKC[d] 抗体
  • PRKCD 抗体
  • tpa-1 抗体
  • wu:fb09d10 抗体
  • wu:fv43b11 抗体
  • zgc:56558 抗体

Protein level used designations for PKCd

protein kinase C delta type , protein kinase-delta2 , protein kinase C, delta , protein kinase C delta type-like , protein kinase C delta VIII , tyrosine-protein kinase PRKCD , nPKC-delta , protein kinase C delta variant IX , protein kinase C, delta IV , protein kinase C, delta V , protein kinase C[d] , protein kinase C delta , PKA C-alpha , cAMP-dependent protein kinase catalytic subunit alpha , sperm cAMP-dependent protein kinase catalytic subunit

GENE ID SPECIES
334571 Danio rerio
404227 Xenopus laevis
733756 Xenopus (Silurana) tropicalis
100230711 Taeniopygia guttata
100294651 Ovis aries
100395399 Callithrix jacchus
100452668 Pongo abelii
100591028 Nomascus leucogenys
5580 Homo sapiens
18753 Mus musculus
170538 Rattus norvegicus
505708 Bos taurus
100008966 Oryctolagus cuniculus
100126848 Sus scrofa
494005 Canis lupus familiaris
415905 Gallus gallus
101107639 Ovis aries
18747 Mus musculus
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