anti-MST1R (MST1R) 抗体产品概述

Full name:
anti-Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) 抗体 (MST1R)
在www.antibodies-online.cn可供213 Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R) 抗体的24不同的供货商。 再加上,我们可以发MST1R 蛋白 (20)MST1R 试剂盒 (9)和数多这个蛋白质的别的产品。 总共248 MST1R产品已列进来了。
别名:
CD136, Cdw136, Fv-2, Fv2, Ptk8, Ron, Stk
列出全部抗体 基因 基因ID UniProt
MST1R 4486 Q04912
MST1R 19882 Q62190
MST1R 300999  

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  1. Human Polyclonal MST1R Primary Antibody for EIA, WB - ABIN359935 : Maggiora, Lorenzato, Fracchioli, Costa, Castagnaro, Arisio, Katsaros, Massobrio, Comoglio, Flavia Di Renzo: The RON and MET oncogenes are co-expressed in human ovarian carcinomas and cooperate in activating invasiveness. in Experimental cell research 2003 (PubMed)
    Show all 6 references for 359935

  2. Human Polyclonal MST1R Primary Antibody for EIA, WB - ABIN453814 : Santoro, Gaudino, Marchisio: The MSP receptor regulates alpha6beta4 and alpha3beta1 integrins via 14-3-3 proteins in keratinocyte migration. in Developmental cell 2003 (PubMed)
    Show all 5 references for 453814

  3. Human Polyclonal MST1R Primary Antibody for WB - ABIN392048 : Penengo, Rubin, Yarden, Gaudino: c-Cbl is a critical modulator of the Ron tyrosine kinase receptor. in Oncogene 2003 (PubMed)
    Show all 4 references for 392048

  4. Human Monoclonal MST1R Primary Antibody for ELISA - ABIN1998917 : Ronsin, Muscatelli, Mattei, Breathnach: A novel putative receptor protein tyrosine kinase of the met family. in Oncogene 1993 (PubMed)
    Show all 3 references for 1998917

  5. Human Monoclonal MST1R Primary Antibody for ELISA, WB - ABIN969384 : Lee, Chen, Chow, Su, Lin, Guo: Prognostic significance of co-expression of RON and MET receptors in node-negative breast cancer patients. in Clinical cancer research : an official journal of the American Association for Cancer Research 2005 (PubMed)
    Show all 3 references for 969384

  6. Human Polyclonal MST1R Primary Antibody for WB - ABIN652379 : Zhou, He, Chen, Wang, Wang: Altered expression of the RON receptor tyrosine kinase in primary human colorectal adenocarcinomas: generation of different splicing RON variants and their oncogenic potential. in Oncogene 2003 (PubMed)
    Show all 3 references for 652379

  7. Human Monoclonal MST1R Primary Antibody for WB - ABIN1105858 : Mallakin, Kutcher, McDowell, Kong, Schuster, Lentsch, Aronow, Leikauf, Waltz: Gene expression profiles of Mst1r-deficient mice during nickel-induced acute lung injury. in American journal of respiratory cell and molecular biology 2005 (PubMed)
    Show all 2 references for 1105858

  8. Human Polyclonal MST1R Primary Antibody for FACS - ABIN4896927 : Sie, den Dunnen, Lourens, Meeuwsen-de Boer, Scherpen, Zomerman, Kampen, Hoving, de Bont: Growth-factor-driven rescue to receptor tyrosine kinase (RTK) inhibitors through Akt and Erk phosphorylation in pediatric low grade astrocytoma and ependymoma. in PLoS ONE 2015 (PubMed)

更多抗MST1R的相互作用对抗体

Human Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R) interaction partners

  1. Findings indicate a role of the RON tyrosine kinase receptor (显示 NTRK1 抗体) in pancreatic cancer and suggest RON as a potential therapeutic target.

  2. High expression of RON is associated with drug resistance in bladder cancer.

  3. complete loss of one or both MET and RON, as well as their overexpression, is a poor prognostic factor in patients with extrahepatic cholangiocarcinoma, probably due to the high rate of lymph-node metastasis

  4. Study identified four novel uniquely spliced RON transcripts in small cell lung carcinoma (SCLC) and Non-SCLC cell lines.

  5. the MST1R variant c.G917A:p.R306H is highly associated with nasopharyngeal carcinoma (odds ratio of 9.0).

  6. Results show that under hypoxia, nuclear RON activates non-homologous end joining DNA repair by interacting with Ku70 (显示 XRCC6 抗体) and DNA-PKcs (显示 PRKDC 抗体) and confers chemoresistance.

  7. Aberrant glycosylation of the RON receptor was shown as an alternative mechanism of oncogenic activation.

  8. Data demonstrated upregulated RON isoform expression and significant changes in splicing factor (显示 SLU7 抗体) expression in primary ovarian cancer suggesting a regulatory interplay of splicing factor (显示 SLU7 抗体) and RON alternative splicing pattern in ovarian cancer.

  9. Activation of RON as an alternate mechanism in the development of CRPC.

  10. the prognostic significance of MET is limited in early stage disease. MET+/RON+ patients had higher overall recurrence rates than those with the other expression patterns

Mouse (Murine) Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R) interaction partners

  1. this study shows that Ron is expressed in a subpopulation of macrophages during chronic inflammation induced by obesity that exhibit a repair phenotype as determined by the expression of arginase 1 (显示 ARG1 抗体)

  2. Report Ron receptor-dependent gene regulation of inflammatory/anti-inflammatory gene expression in Kupffer cells during endotoxemia.

  3. Ron knockdown further sensitized breast cancer cells to the growth inhibitory effects of vitamin D3, while constitutive activation of beta-catenin (显示 CTNNB1 抗体) reverted the effects of vitamin D3.

  4. Studies demonstrate that DEK (显示 DEK 抗体) overexpression, due in part to Ron receptor activation, drives breast cancer progression through the induction of Wnt (显示 WNT2 抗体)/beta-catenin (显示 CTNNB1 抗体) signaling.

  5. A previously unknown function for the Ron receptor in mediating High Fat Diet-induced obesity and metabolic dysregulation.

  6. important functional roles for Ron in inflammatory bowel diseases by regulating healing of the colonic epithelium and by controlling cytokine secretion

  7. DC-STAMP (显示 TM7SF4 抗体), Siglec-15 (显示 SIGLEC15 抗体), Tspan7 (显示 TSPAN7 抗体) and Mst1r expression was downregulated by docosahexaenoic acid, but not eicosapentaenoic acid during osteoclastogenesis in vitro.

  8. Stem cell-derived tyrosine kinase plays a role in regulating macrophage recruitment and activation in the liver following acetaminophen administration and in hepatotoxicity.

  9. studies show a critical role for the Ron receptor in the tumor microenvironment, whereby Ron loss in tumor-associated macrophages inhibits prostate cancer cell growth, at least in part, by derepressing the activity of CD8 (显示 CD8A 抗体)(+) T cells

  10. Identify a novel signaling mechanism by which the Ron receptor regulates acute liver failure progression.

MST1R 抗原简介

Antigen Summary

This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta subunits, generated by proteolytic cleavage of a single-chain precursor. The beta subunit undergoes tyrosine phosphorylation upon stimulation by MSP. This protein is expressed on the ciliated epithelia of the mucociliary transport apparatus of the lung, and together with MSP, thought to be involved in host defense. Alternatively spliced transcript variants encoding different isoforms with different structural and biochemical properties have been described (PMID:8816464).

Alternative names and synonyms associated with MST1R

  • macrophage stimulating 1 receptor (c-met-related tyrosine kinase) (MST1R) 抗体
  • macrophage stimulating 1 receptor (c-met-related tyrosine kinase) (Mst1r) 抗体
  • CD136 抗体
  • Cdw136 抗体
  • Fv-2 抗体
  • Fv2 抗体
  • Ptk8 抗体
  • Ron 抗体
  • Stk 抗体

Protein level used designations for MST1R

MSP receptor , MST1R variant RON30 , MST1R variant RON62 , PTK8 protein tyrosine kinase 8 , RON variant 21 , RON variant E2E3 , c-met-related tyrosine kinase , macrophage-stimulating protein receptor , p185-Ron , soluble RON variant 1 , soluble RON variant 2 , soluble RON variant 3 , soluble RON variant 4 , friend virus susceptibility 2 , macrophage-stimulating protein receptor precursor (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) , receptor protein tyrosine kinase, c-met-related , stem cell-derived tyrosine kinase , protein tyrosine kinase 8 , tyrosine kinase receptor ron

GENE ID SPECIES
4486 Homo sapiens
19882 Mus musculus
300999 Rattus norvegicus
444854 Canis lupus familiaris
100626292 Sus scrofa
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