EPH Receptor A2 蛋白 (EPHA2)产品概述

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EPH Receptor A2 蛋白 (EPHA2)
在www.antibodies-online.cn可供17 EPH Receptor A2 (EPHA2) 蛋白的6不同的供货商。 再加上,我们可以发EPH Receptor A2 抗体 (351)EPH Receptor A2 试剂盒 (5)和数多这个蛋白质的别的产品。 总共396 EPH Receptor A2产品已列进来了。
别名:
ARCC2, AW545284, CTPA, CTPP1, CTRCT6, Eck, epha2, MGC89505, Myk2, Sek-2, Sek2
列出全部蛋白 基因 基因ID UniProt
EPHA2 1969 P29317
EPHA2 13836 Q03145
大鼠 EPHA2 EPHA2 366492  

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引用最多的EPH Receptor A2 蛋白

  1. Mouse (Murine) EPH Receptor A2 Protein expressed in Human Cells - ABIN2008013 : Nowakowski, Cronin, McRee, Knuth, Nelson, Pavletich, Rogers, Sang, Scheibe, Swanson, Thompson: Structures of the cancer-related Aurora-A, FAK, and EphA2 protein kinases from nanovolume crystallography. in Structure (London, England : 1993) 2002 (PubMed)
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  2. Human EPH Receptor A2 Protein expressed in Human Cells - ABIN2006004 : Rikova, Guo, Zeng, Possemato, Yu, Haack, Nardone, Lee, Reeves, Li, Hu, Tan, Stokes, Sullivan, Mitchell, Wetzel, Macneill, Ren, Yuan, Bakalarski, Villen, Kornhauser, Smith, Li, Zhou, Gygi, Gu et al.: Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer. ... in Cell 2007 (PubMed)
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  3. Human EPH Receptor A2 Protein expressed in Baculovirus infected Insect Cells - ABIN2006006 : Gerhard, Wagner, Feingold, Shenmen, Grouse, Schuler, Klein, Old, Rasooly, Good, Guyer, Peck, Derge, Lipman, Collins, Jang, Sherry, Feolo, Misquitta, Lee, Rotmistrovsky, Greenhut, Schaefer, Buetow et al.: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ... in Genome research 2004 (PubMed)
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更多EPH Receptor A2互动伙伴

Human EPH Receptor A2 (EPHA2) interaction partners

  1. These findings show that radiation induces S897 EphA2 phosphorylation, an event associated with increased cell survival. Therefore, targeting pathways that mediate EphA2 S897 phosphorylation may be a beneficial strategy to reduce radioresistance.

  2. Our findings broaden the spectrum of causative mutations in EPHA2 gene for congenital cataract and suggest that WES is an efficient strategy to scan variants in known causative genes for genetically heterogeneous diseases.

  3. Afadin (AFDN), a cytoskeletal and junction-associated protein, was present in 2D and 3D keratinocyte cultures, and validated as a so-far-unknown EphA2-interacting protein.

  4. EphA2, a member of the large family of Ephrin receptor tyrosine kinases, is a functional signaling receptor for progranulin (显示 GRN 蛋白).

  5. EphA2 have the ability to negatively regulate the radiosensitivity of HCC (显示 FAM126A 蛋白) 97H cells, which mainly depends on 38MAPK-mediated signal pathways.

  6. both EphA2 and EphB4 (显示 EPHB4 蛋白) show potential as target for image-guided colorectal cancer surgery, but EphB4 (显示 EPHB4 蛋白) seems to have the best characteristics with respect to tumor/normal mucosa distribution

  7. EphA2 is a key downstream target of the MEK (显示 MAP2K1 蛋白)/ERK (显示 EPHB2 蛋白)/RSK (显示 RPS6KA1 蛋白) signaling pathway in the regulation of glioblastoma cell proliferation.

  8. possible involvement of membrane-type 1 matrix metalloproteinase (显示 MMP14 蛋白) processing of erythropoietin (显示 EPO 蛋白)-producing hepatocellular receptor-2in invasiveness of cutaneous cutaneous squamous cell carcinoma

  9. cells with Lipoplatin. The combined effects of siRNA-EphA2 and Lipoplatin were determined. We report that silencing EphA2 significantly enhanced the cellular sensitivity of lung tumor and MPM cells to Lipoplatin and maybe a potential therapy for lung cancer.

  10. Data show that the EphA2 ectodomain harbors a membrane-binding motif in the FN2 (显示 FN1 蛋白) domain which preferentially interacts with anionic lipids.

Mouse (Murine) EPH Receptor A2 (EPHA2) interaction partners

  1. Collectively, these data suggest that ATRA attenuates bleomycin-induced pulmonary fibrosis by regulating EphA2-EphrinA1 and PI3K-Akt (显示 AKT1 蛋白) signaling.

  2. Lipopolysaccharide exposure significantly up-regulated EphA2 and EphrinA1 expression.

  3. modulation of EphA2 signaling might contribute to effective transplantation of tissue-specific resident macrophages and/or monocytes

  4. Our data suggest that EphA2 is closely related to the formation of osteoblasts and resorption of osteoclast and is likely to play an role in bone resorption induced in chronic periodontitis

  5. We examined the roles of ephrin-A2 (显示 EFNA2 蛋白) and ephrin-A5 (显示 EFNA5 蛋白) signaling in contralateral targeting and topographic ordering in the ventral cochlear nucleus

  6. EphA2 acts as a KRas cooperative tumor suppressor

  7. Data shows that modulation of angiostatic factor Slit2 by EphA2 receptor regulates endothelial responses to VEGF-mediated angiogenesis and tumor neovascularization.

  8. Sporozoites productively infected hepatocytes with high EphA2 expression, and the deletion of EphA2 protected mice from liver infection.

  9. EphA2-mutant mice are more prone to hyperglycemia-induced increased injury and decreased survival.

  10. EphA2 receptor silencing attenuates the extent and inflammation of atherosclerotic lesions in ApoE (显示 APOE 蛋白)(-/-) mice.

Cow (Bovine) EPH Receptor A2 (EPHA2) interaction partners

  1. The present study successfully assessed the expression pattern of miR26b in the pituitary tissue of Yanbian cattle, and also confirmed that EphA2 was a target gene of miR26b in Yanbian cattle in vitro.

蛋白简介EPH Receptor A2 (EPHA2)

蛋白简介

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Mutations in this gene are the cause of certain genetically-related cataract disorders.

Alternative names and synonyms associated with EPH Receptor A2 (EPHA2)

  • EPH receptor A2 (EPHA2)
  • EphA2 (epha2)
  • epoxide hydrolase (ephA2)
  • Eph receptor A2 (Epha2)
  • ARCC2 蛋白
  • AW545284 蛋白
  • CTPA 蛋白
  • CTPP1 蛋白
  • CTRCT6 蛋白
  • Eck 蛋白
  • epha2 蛋白
  • MGC89505 蛋白
  • Myk2 蛋白
  • Sek-2 蛋白
  • Sek2 蛋白

Protein level used designations for EPH Receptor A2 蛋白 (EPHA2)

EPH receptor A2 , protein tyrosine kinase EphA2 , EphA2 , ephrin receptor EphA2 , ephrin type-A receptor 2 , epoxide hydrolase , epithelial cell receptor protein tyrosine kinase , soluble EPHA2 variant 1 , tyrosine-protein kinase receptor ECK , epithelial cell kinase , tyrosine-protein kinase receptor MPK-5 , tyrosine-protein kinase receptor SEK-2

GENE ID SPECIES
100053644 Equus caballus
395311 Gallus gallus
448450 Xenopus (Silurana) tropicalis
456472 Pan troglodytes
692343 Macaca mulatta
1214785 Streptomyces avermitilis MA-4680
100591506 Nomascus leucogenys
1969 Homo sapiens
13836 Mus musculus
366492 Rattus norvegicus
487421 Canis lupus familiaris
512798 Bos taurus
771550 Gallus gallus
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