anti-AXL (AXL) 抗体产品概述

Full name:
anti-AXL Receptor tyrosine Kinase 抗体 (AXL)
在www.antibodies-online.cn可供295 AXL Receptor tyrosine Kinase (AXL) 抗体的26不同的供货商。 再加上,我们可以发AXL 试剂盒 (30)AXL 蛋白 (20)和数多这个蛋白质的别的产品。 总共362 AXL产品已列进来了。
别名:
AI323647, Ark, JTK11, Tyro7, Ufo

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引用最多的anti-AXL 抗体

  1. Human Polyclonal AXL Primary Antibody for FACS, IHC (p) - ABIN391878 : Lee, Strunk, Spritz: A survey of protein tyrosine kinase mRNAs expressed in normal human melanocytes. in Oncogene 1993 (PubMed)
    Show all 4 references for 391878

  2. Human Polyclonal AXL Primary Antibody for EIA, WB - ABIN359786 : Janssen, Schulz, Steenvoorden, Schmidberger, Strehl, Ambros, Bartram: A novel putative tyrosine kinase receptor with oncogenic potential. in Oncogene 1991 (PubMed)
    Show all 4 references for 359786

  3. Human Polyclonal AXL Primary Antibody for EIA, WB - ABIN359784 : OBryan, Frye, Cogswell, Neubauer, Kitch, Prokop, Espinosa, Le Beau, Earp, Liu: axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase. in Molecular and cellular biology 1991 (PubMed)
    Show all 4 references for 359784

  4. Human Polyclonal AXL Primary Antibody for FACS, IHC (p) - ABIN391876 : Partanen, Mäkelä, Alitalo, Lehväslaiho, Alitalo: Putative tyrosine kinases expressed in K-562 human leukemia cells. in Proceedings of the National Academy of Sciences of the United States of America 1991 (PubMed)
    Show all 4 references for 391876

  5. Human Monoclonal AXL Primary Antibody for FACS - ABIN4895642 : Zheng, Hedl, Abraham: TAM receptor-dependent regulation of SOCS3 and MAPKs contributes to proinflammatory cytokine downregulation following chronic NOD2 stimulation of human macrophages. in Journal of immunology (Baltimore, Md. : 1950) 2015 (PubMed)

  6. Human Monoclonal AXL Primary Antibody for FACS - ABIN4895644 : Yumoto, Eber, Wang, Cackowski, Decker, Lee, Nobre, Aguirre-Ghiso, Jung, Taichman: Axl is required for TGF-β2-induced dormancy of prostate cancer cells in the bone marrow. in Scientific reports 2016 (PubMed)

  7. Mouse (Murine) Monoclonal AXL Primary Antibody for FACS - ABIN4899408 : Fujimori, Grabiec, Kaur, Bell, Fujino, Cook, Svedberg, MacDonald, Maciewicz, Singh, Hussell: The Axl receptor tyrosine kinase is a discriminator of macrophage function in the inflamed lung. in Mucosal immunology 2015 (PubMed)

更多抗AXL的相互作用对抗体

Human AXL Receptor tyrosine Kinase (AXL) interaction partners

  1. we identify PROS1 (显示 PROS1 抗体) as a driver of Oral Squamous Cell Carcinoma tumor growth and a modulator of AXL expression

  2. Studies indicate that aberrant AXL receptor tyrosine kinase (AXL) signaling and development of an epithelial-to-mesenchymal transition (EMT (显示 ITK 抗体)) phenotype underlie resistance of anaplastic lymphoma kinase (ALK (显示 ALK 抗体) F1174L)-driven neuroblastoma (显示 ARHGEF16 抗体) (NB) cells to TAE684 and its derivatives.

  3. Studied axl kinase as a negative regulator of an alveolar epithelial cell phenotype; results found that inhibition of Axl kinase could form epithelial adhesion structure and augment surfactant protein production via the MET of human lung multi-potent cells.

  4. AXL is efficiently and sequentially cleaved by alpha- and gamma-secretases in various types of cancer cell lines. The AXL intracellular domain cleavage product translocates into the nucleus via a nuclear localization sequence that harbored a basic HRRKK motif.

  5. a relationship between AXL and the cellular response to DNA damage whereby abrogation of AXL signaling leads to accumulation of the DNA-damage markers gammaH2AX (显示 H2AFX 抗体), 53BP1 (显示 TP53BP1 抗体), and RAD51 (显示 RAD51 抗体).

  6. Small molecule and antibody inhibitors of AXL and MER (显示 MERTK 抗体) have recently been described, and some of these have already entered clinical trials. The optimal design of treatment strategies to maximize the clinical benefit of these AXL and MER (显示 MERTK 抗体) targeting agents are discussed in relation to the different cancer types and the types of resistance encountered.

  7. our results demonstrate that AR can promote melanoma metastasis via altering the miRNA-539-3p/USP13 (显示 USP13 抗体)/MITF (显示 MITF 抗体)/AXL signal and targeting this newly identified signal with AR degradation enhancer ASC (显示 PYCARD 抗体)-J9 may help us to better suppress the melanoma metastasis.

  8. AXL can be an effective therapeutic target in combination with targeted therapy such as PARP (显示 COL11A2 抗体) inhibitors in several different malignancies.

  9. AXL/TAZ (显示 TAZ 抗体)/YAP (显示 YAP1 抗体) expression is associated with poor prognosis in male breast cancer patients.

  10. High AXL expression is associated with Paclitaxel resistance in breast Cancers.

Mouse (Murine) AXL Receptor tyrosine Kinase (AXL) interaction partners

  1. Both Axl+/- and Axl-/- suckling mice supported the replication of Zika virus.

  2. reciprocal activation of Axl and Mer (显示 ERH 抗体) receptor tyrosine kinases has a major impact on the outcome of renal inflammation.

  3. Axl is critical for survival of T lymphocytes, especially during vascular remodeling in hypertension.

  4. Axl, Mertk (显示 MERTK 抗体) and Tyro3 (显示 TYRO3 抗体) receptors are not required for Zika virus entry and infection.

  5. Axl plays an essential role in the regulation of NK cell development as well as natural killer effector function.

  6. Matrix metalloproteases ADAM10 (显示 ADAM10 抗体) and TACE (ADAM17 (显示 ADAM17 抗体)) cleave AXL receptor tyrosine kinase (Axl) in lupus-prone leukocytes.

  7. Gas6 (显示 GAS6 抗体)/Axl and Akt (显示 AKT1 抗体)/FoxO1a (显示 FOXO1 抗体) were involved in protective effects of testosterone on VSMCs senescence and collagen synthesis.

  8. Axl allows specific identification of airway macrophages, and that its expression is critical for macrophage functional compartmentalization in the airspaces or lung interstitium.

  9. results establish TAM (显示 CCNA1 抗体) receptors as both controllers of microglial physiology and potential targets for therapeutic intervention in central nervous system disease

  10. These results suggest that TAM (显示 CCNA1 抗体) receptors support NSCs survival, proliferation and differentiation by regulating expression of neurotrophins, especially the nerve growth factor.

Cow (Bovine) AXL Receptor tyrosine Kinase (AXL) interaction partners

  1. activation of receptor tyrosine kinase (显示 RET 抗体) Axl inhibits the osteogenic differentiation of vascular pericytes.

AXL 抗原简介

Antigen Summary

The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified.

Alternative names and synonyms associated with AXL

  • AXL receptor tyrosine kinase (AXL) 抗体
  • AXL receptor tyrosine kinase (Axl) 抗体
  • Axl receptor tyrosine kinase (Axl) 抗体
  • AI323647 抗体
  • Ark 抗体
  • JTK11 抗体
  • Tyro7 抗体
  • Ufo 抗体

Protein level used designations for AXL

AXL oncogene , AXL transforming sequence/gene , tyrosine-protein kinase receptor UFO , adhesion-related kinase , ufo oncogene homolog

GENE ID SPECIES
100064907 Equus caballus
558 Homo sapiens
26362 Mus musculus
308444 Rattus norvegicus
484490 Canis lupus familiaris
100144875 Sus scrofa
516598 Bos taurus
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