anti-Histone Deacetylase 5 (HDAC5) 抗体产品概述

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anti-Histone Deacetylase 5 抗体 (HDAC5)
在www.antibodies-online.cn可供178 Histone Deacetylase 5 (HDAC5) 抗体的25不同的供货商。 再加上,我们可以发Histone Deacetylase 5 试剂盒 (11)Histone Deacetylase 5 蛋白 (5)和数多这个蛋白质的别的产品。 总共203 Histone Deacetylase 5产品已列进来了。
别名:
AI426555, ATHDA5, DKFZp459O115, HD5, Hd6, HDA5, Hdac4, Hdac5, histone deacetylase 5, MAF19.7, MAF19_7, mHDA1, mHDA2, mKIAA0600, NY-CO-9, Sfc6
列出全部抗体 基因 基因ID UniProt
HDAC5 10014 Q9UQL6
HDAC5 15184  
HDAC5 84580  

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  1. Human Monoclonal HDAC5 Primary Antibody for IF, WB - ABIN393805 : Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010 (PubMed)
    Show all 5 references for 393805

  2. Human Polyclonal HDAC5 Primary Antibody for ChIP, WB - ABIN2668266 : Basile, Mantovani, Imbriano: DNA damage promotes histone deacetylase 4 nuclear localization and repression of G2/M promoters, via p53 C-terminal lysines. in The Journal of biological chemistry 2006 (PubMed)
    Show all 5 references for 2668266

  3. Human Polyclonal HDAC5 Primary Antibody for IHC (p), IP - ABIN127240 : Wang, Bertos, Vezmar, Pelletier, Crosato, Heng, Thng, Han, Yang: HDAC4, a human histone deacetylase related to yeast HDA1, is a transcriptional corepressor. in Molecular and cellular biology 1999 (PubMed)
    Show all 2 references for 127240

  4. Human Polyclonal HDAC5 Primary Antibody for IHC (p), WB - ABIN196932 : Döppler, Storz, Li, Comb, Toker: A phosphorylation state-specific antibody recognizes Hsp27, a novel substrate of protein kinase D. in The Journal of biological chemistry 2005 (PubMed)
    Show all 2 references for 196932

  5. Human Polyclonal HDAC5 Primary Antibody for IP, IHC - ABIN223300 : Yamaguchi, Chakraborty, Pasek, Molkentin, Meissner: Dysfunctional ryanodine receptor and cardiac hypertrophy: role of signaling molecules. in American journal of physiology. Heart and circulatory physiology 2011 (PubMed)
    Show all 2 references for 223300

  6. Human Polyclonal HDAC5 Primary Antibody for IHC (p), WB - ABIN197340 : McKinsey, Zhang, Lu, Olson: Signal-dependent nuclear export of a histone deacetylase regulates muscle differentiation. in Nature 2000 (PubMed)
    Show all 2 references for 197340

  7. Human Polyclonal HDAC5 Primary Antibody for ICC, IF - ABIN4316758 : Baek, Park, Rhim, Park, Kim, Kim, Nam: Immunohistochemical Characterization of Histone Deacetylase as a Potential Prognostic Marker and Therapeutic Target in Endometrial Stromal Sarcoma. in Anticancer research 2016 (PubMed)

更多抗Histone Deacetylase 5的相互作用对抗体

Human Histone Deacetylase 5 (HDAC5) interaction partners

  1. HDAC5 is a negative predictor of disease-free and overall survival in pancreatic neuroendocrine tumor patients.

  2. Interference with both glucose and glutamine (显示 GFPT1 抗体) supply in HDAC5-inhibited cancer cells significantly increases apoptotic cell death.

  3. these results suggest that HDAC5 is critical in regulating LSD1 (显示 KDM1A 抗体) protein stability through post-translational modification, and the HDAC5-LSD1 (显示 KDM1A 抗体) axis has an important role in promoting breast cancer development and progression.

  4. The expression of HDAC5 was significantly increased in endothelial cells (ECs) from patients with systemic sclerosis (SSc (显示 CYP11A1 抗体)) compared to healthy control endothelial cells. Silencing of HDAC5 in SSc (显示 CYP11A1 抗体) ECs restored normal angiogenesis. HDAC5 knockdown followed by ATAC (显示 XCL1 抗体)-seq assay in SSc (显示 CYP11A1 抗体) ECs identified key HDAC5-regulated genes involved in angiogenesis and fibrosis, such as CYR61 (显示 CYR61 抗体), PVRL2 (显示 PVRL2 抗体), and FSTL1 (显示 FSTL1 抗体).

  5. the migration and invasion of hepatocellular carcinoma cells were impaired by knockdown of histone deacetylase 5 or hypoxia-inducible factor-1alpha but rescued when eliminating homeodomain-interacting protein kinase-2 (显示 HIPK2 抗体) in hepatocellular carcinoma cells, which suggested the critical role of histone deacetylase 5-homeodomain-interacting protein kinase-2 (显示 HIPK2 抗体)-hypoxia-inducible factor-1alpha pathway in hypoxia-induced metastasis.

  6. HDAC5 inhibits hepatic lipogenic genes expression by attenuating the transcriptional activity of liver X receptor.

  7. HDAC5 promotes cellular proliferation through the upregulation of cMet, and may provide a novel therapeutic target for the treatment of patients with Wilms' tumor.

  8. HDAC5 and HDAC6 (显示 HDAC6 抗体) were highly expressed in melanoma cells but exhibited low expression levels in normal skin cells.

  9. Formononetin-combined therapy may enhance the therapeutic efficacy of doxorubicin in glioma cells by preventing EMT (显示 ITK 抗体) through inhibition of HDAC5.

  10. These results suggest a strong regulatory function of HDAC5 in the pro-inflammatory response of macrophages.

Mouse (Murine) Histone Deacetylase 5 (HDAC5) interaction partners

  1. Specific HDAC6 (显示 HDAC6 抗体) inhibitor, tubacin, reduced cyst growth by inhibiting proliferation of cyst-lining epithelial cells, downregulated cyclic AMP (显示 TMPRSS5 抗体) levels, and improved renal function in mouse model of autosomal dominant polycystic kidney disease (ADPKD). Thus, HDAC6 (显示 HDAC6 抗体) could play a role in cyst formation and could serve as a potential therapeutic target in ADPKD.

  2. Data suggest that a switch in post-translational processing of Tau from acetylation at Lys321 to phosphorylation at Ser324 coordinately regulates Tau aggregation and may be relevant in tauopathy and Alzheimer disease; acetylation/phosphorylation of Tau appears to be controlled by Hdac6 (histone deacetylase 6 (显示 HDAC6 抗体) protein).

  3. ARID1A (显示 ARID1A 抗体) mutation inactivates the apoptosis-promoting function of p53 (显示 TP53 抗体) by upregulating HDAC6 (显示 HDAC6 抗体), indicating that pharmacological inhibition of HDAC6 (显示 HDAC6 抗体) is a therapeutic strategy for ARID1A (显示 ARID1A 抗体)-mutated cancers.

  4. Fatty acids prevent CIDEC (显示 CIDEC 抗体) deacetylation by promoting the dissociation of CIDEC (显示 CIDEC 抗体) from HDAC6 (显示 HDAC6 抗体), resultin in increased association of CIDEC (显示 CIDEC 抗体) with PCAF (显示 KAT2B 抗体) on the endoplasmic reticulum.

  5. findings showed that CAMDI regulates neuronal migration through the modulation of HDAC6 and indicate that HDAC6 hyperactivation by CAMDI deletion causes psychiatric behaviors, at least in part, through delayed radial migration due to impaired centrosomes

  6. HDAC6 (显示 HDAC6 抗体) contributes to the pathogenesis of rhabdomyolysis-induced acute kidney injury.

  7. This paper presents data for the first time directly supporting the role of HDAC5 as a scaffold recruiting a chromatin modifying co-repressor complex to specific transcription factors on unique gene promoters. These data for HDAC5 may reflect one of the functions of class IIa HDACs in transcriptional regulation distinct from its catalytic activity.

  8. In coordination with increased HDAC6 (显示 HDAC6 抗体) phosphorylation, cigarette smoke extract inhibited Akt (显示 AKT1 抗体) and activated glycogen synthase kinase (GSK)-3beta (显示 GSK3b 抗体).

  9. This study demonstrated that decreased HDAC5 function is able to exacerbate the long-term behavioral effects of adverse rearing environment in mice

  10. Cathepsin S (显示 CTSS 抗体) activity controls injury-related vascular remodeling via TLR2 (显示 TLR2 抗体)/p38MAPK (显示 MAPK14 抗体)/PI3K/Akt (显示 AKT1 抗体)/p-HDAC6 (显示 HDAC6 抗体) signaling pathway.

Cow (Bovine) Histone Deacetylase 5 (HDAC5) interaction partners

  1. Protein kinase D-HDAC5 pathway plays an important role in VEGF regulation of gene transcription and angiogenesis

Arabidopsis thaliana Histone Deacetylase 5 (HDAC5) interaction partners

  1. Regulation of flowering time by the histone deacetylase HDA5

Histone Deacetylase 5 (HDAC5) 抗原简介

Antigen Summary

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Histone Deacetylase 5 (HDAC5)

  • histone deacetylase 5 (HDAC5) 抗体
  • histone deacetylase 5 (Hdac5) 抗体
  • histone deacetylase 5 (HDA05) 抗体
  • histone deacetylase 6 (Hdac6) 抗体
  • AI426555 抗体
  • ATHDA5 抗体
  • DKFZp459O115 抗体
  • HD5 抗体
  • Hd6 抗体
  • HDA5 抗体
  • Hdac4 抗体
  • Hdac5 抗体
  • histone deacetylase 5 抗体
  • MAF19.7 抗体
  • MAF19_7 抗体
  • mHDA1 抗体
  • mHDA2 抗体
  • mKIAA0600 抗体
  • NY-CO-9 抗体
  • Sfc6 抗体

Protein level used designations for HDAC5

histone deacetylase 5 , antigen NY-CO-9 , HD5 , histone deacetylase 4 , histone deacetylase mHDA1 , histone deacetylase mHDA2 , scurfy candidate 6

GENE ID SPECIES
100172968 Pongo abelii
10014 Homo sapiens
15184 Mus musculus
84580 Rattus norvegicus
490941 Canis lupus familiaris
504242 Bos taurus
100458256 Pongo abelii
100689350 Cricetulus griseus
836227 Arabidopsis thaliana
15185 Mus musculus
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