anti-HDAC4 (HDAC4) 抗体产品概述

Full name:
anti-Histone Deacetylase 4 抗体 (HDAC4)
在www.antibodies-online.cn可供341 Histone Deacetylase 4 (HDAC4) 抗体的37不同的供货商。 再加上,我们可以发HDAC4 试剂盒 (17)HDAC4 蛋白 (15)和数多这个蛋白质的别的产品。 总共393 HDAC4产品已列进来了。
4932408F19Rik, AHO3, AI047285, BDMR, CG1770, DanaGF18710, dana_GLEANR_19966, dHDAC4, Dmel\\CG1770, dmHDA405, GC1770, GF18710, HA6116, HD4, HDAC, HDAC-4, HDAC-A, HDAC4, HDAC4a, HDACA, wu:fa96d08, wu:fc56f08, zgc:152701

最受欢迎的抗anti-HDAC4 (HDAC4) 抗体


抗Human HDAC4 抗体:

抗Mouse (Murine) HDAC4 抗体:

抗Rat (Rattus) HDAC4 抗体:

所有可销售的anti-HDAC4 抗体


引用最多的anti-HDAC4 抗体

  1. Human Polyclonal HDAC4 Primary Antibody for ICC, IF - ABIN269450 : Geng, Cuneo, Fu, Tu, Atadja, Hallahan: Histone deacetylase (HDAC) inhibitor LBH589 increases duration of gamma-H2AX foci and confines HDAC4 to the cytoplasm in irradiated non-small cell lung cancer. in Cancer research 2006 (PubMed)
    Show all 5 references for 269450

  2. Human Polyclonal HDAC4 Primary Antibody for EIA, WB - ABIN493047 : Bolden, Peart, Johnstone: Anticancer activities of histone deacetylase inhibitors. in Nature reviews. Drug discovery 2006 (PubMed)
    Show all 5 references for 493047

  3. Human Polyclonal HDAC4 Primary Antibody for EIA, WB - ABIN356644 : Chan, Sun, Yang, Zhu, Wu: Functional characterization of an amino-terminal region of HDAC4 that possesses MEF2 binding and transcriptional repressive activity. in The Journal of biological chemistry 2003 (PubMed)
    Show all 5 references for 356644

  4. Human Polyclonal HDAC4 Primary Antibody for IF, WB - ABIN197338 : Wang, Kruhlak, Wu, Bertos, Vezmar, Posner, Bazett-Jones, Yang: Regulation of histone deacetylase 4 by binding of 14-3-3 proteins. in Molecular and cellular biology 2000 (PubMed)
    Show all 2 references for 197338

  5. Human Polyclonal HDAC4 Primary Antibody for WB - ABIN196930 : Grozinger, Schreiber: Regulation of histone deacetylase 4 and 5 and transcriptional activity by 14-3-3-dependent cellular localization. in Proceedings of the National Academy of Sciences of the United States of America 2000 (PubMed)
    Show all 2 references for 196930

  6. Human Polyclonal HDAC4 Primary Antibody for WB - ABIN387951 : Kao, McKenna, Guenther, Muschel, Lazar, Yen: Histone deacetylase 4 interacts with 53BP1 to mediate the DNA damage response. in The Journal of cell biology 2003 (PubMed)
    Show all 2 references for 387951

  7. Cow (Bovine) Polyclonal HDAC4 Primary Antibody for WB - ABIN2778342 : Lee, Lin, Luo, Lee, Lee, Aird, Hwang, Yang et al.: Tumor necrosis factor-alpha enhances neutrophil adhesiveness: induction of vascular cell adhesion molecule-1 via activation of Akt and CaM kinase II and modifications of histone acetyltransferase and ... in Molecular pharmacology 2008 (PubMed)

  8. Human Polyclonal HDAC4 Primary Antibody for IHC, WB - ABIN223298 : Cao, Li, Zhu, Shen, Han, Zhang, Yu, Wang, Wu, Chen, Sun, Tang, Zhao, Qiao, Hou, Mao: The antiparasitic clioquinol induces apoptosis in leukemia and myeloma cells by inhibiting histone deacetylase activity. in The Journal of biological chemistry 2013 (PubMed)


Fruit Fly (Drosophila melanogaster) Histone Deacetylase 4 (HDAC4) interaction partners

  1. We also demonstrate that HDAC4 and Ubc9 (显示 UBE2I 抗体) interact genetically during memory formation, opening new avenues for investigating the mechanisms through which HDAC4 regulates memory formation and other neurological processes.

  2. RNAi-mediated knockdown of HDAC4 in Drosophila dampens circadian function.

  3. HDAC4 is not only a repressor of long-term memory, but also modulates normal memory formation

  4. dHDAC4, is a novel, catalytically active class II Drosophila histone deacetylase (显示 HDAC1 抗体) and is involved in the segmentation regulatory pathway and suggested complex transcriptional regulation as a potential mechanism that controls its expression

Human Histone Deacetylase 4 (HDAC4) interaction partners

  1. level of myotubes MTM1 (显示 MTM1 抗体) mutations do not dramatically affect calcium homeostasis and calcium release mediated through the ryanodine receptor 1 (显示 RYR1 抗体), though they do affect myotube size and nuclear content..mature muscles such as those obtained from patient muscle biopsies exhibit a significant decrease in expression of the ryanodine receptor 1 (显示 RYR1 抗体), a decrease in muscle-specific (显示 EIF3K 抗体) microRNAs and a considerable up-regulation of HDAC4.

  2. 7-amino-4-methylcoumarin did not affect acetyllysine preference in a multiply acetylated substrate. In contrast, AMC significantly enhanced KDAC6 substrate affinity, greatly reduced Sirt1 (显示 SIRT1 抗体) activity, eliminated the substrate sequence specificity of KDAC4, and had no consistent effect with KDAC8 substrates.

  3. Suggest that HDAC4 and HDAC6 (显示 HDAC6 抗体) are guardians of irradiation-induced DNA damage and stemness, thus promoting radioresistance in glioblastoma cells.

  4. TGF-beta1 (显示 TGFB1 抗体) increases NADPH oxidase 4 (NOX4 (显示 NOX4 抗体)) mRNA and protein expression in normal human lung fibroblasts (NHLFs) and causes nuclear export of HDAC4.

  5. elevated HO-1 (显示 HMOX1 抗体) produced less reactive oxygen species, resulting in nuclear localization of HDAC4 and miR (显示 MLXIP 抗体)-206 repression.

  6. Results show that HDAC4 is a direct target of miR (显示 MLXIP 抗体)-29b in multiple myeloma cells and its high mRNA expression inversely correlates with miR (显示 MLXIP 抗体)-29b levels in multiple myeloma samples.

  7. in leiomyosarcomas (LMS), this two-faced trait of MEF2 (显示 MEF2A 抗体) is relevant for tumor aggressiveness. Class IIa HDACs are overexpressed in 22% of LMS, where high levels of MEF2 (显示 MEF2A 抗体), HDAC4 and HDAC9 (显示 HDAC9 抗体) inversely correlate with overall survival. The knock out of HDAC9 (显示 HDAC9 抗体) suppresses the transformed phenotype of LMS cells, by restoring the transcriptional proficiency of some MEF2 (显示 MEF2A 抗体)-target loci

  8. Collectively, we suggest that VSV treatment will be a useful therapeutic strategy for HCV-infected hepatocellular carcinoma cells because HCV core protein suppresses the anti-viral threshold by down-regulation of the STAT1 (显示 STAT1 抗体)-HDAC4 signaling axis.

  9. In osteoarthritis (OA) chondrocytes, hydrostatic pressure (HP) restores the expression levels of some miRNAs, downregulates MMP-13 (显示 MMP13 抗体), ADAMTS-5 (显示 ADAMTS5 抗体), and HDAC-4, and modulates the Wnt (显示 WNT2 抗体)/beta-catenin (显示 CTNNB1 抗体) pathway activation.

  10. HDAC4 is a target gene of miR (显示 MLXIP 抗体)-140 and is involved in miR (显示 MLXIP 抗体)-140-mediated suppression of osteosarcoma cells.

Mouse (Murine) Histone Deacetylase 4 (HDAC4) interaction partners

  1. our results imply that under steady stage, HDAC4 (显示 HDAC5 抗体) is not required for the development and function of multiple T cell lineages

  2. HDAC4 (显示 HDAC5 抗体)-mediated SUMOylation of the corepressor DACH1 (显示 DACH1 抗体) is decreased, which protects DACH1 (显示 DACH1 抗体) from proteasomal degradation

  3. The eating-disorder (ED) associated HDAC4 (显示 HDAC5 抗体)(A778T) mutation alters feeding behaviors in female mice. The HDAC4 (显示 HDAC5 抗体)(A778T) mouse line is a novel model of ED-related behaviors and identifies mitochondrial biogenesis as a potential molecular pathway contributing to behavioral deficits.

  4. Nuclear HDAC4 (显示 HDAC5 抗体) binds to chromatin as well as to MEF2A (显示 MEF2A 抗体) transcription factor, leading to histone deacetylation and altered neuronal gene expression. By using a Cdkl5 (显示 CDKL5 抗体) knockout (Cdkl5 (显示 CDKL5 抗体) -/Y) mouse model, we found that hypophosphorylated HDAC4 (显示 HDAC5 抗体) translocates to the nucleus of neural precursor cells, thereby reducing histone 3 acetylation.

  5. Data (including data from studies using knockout mice) suggest that S100A1 (显示 S100A1 抗体) (S-100 calcium-binding protein (显示 GUCA1B 抗体) A1 (显示 BCL2A1 抗体), alpha chain (显示 FCGRT 抗体)) is involved in protein kinase A- (RIIalpha and RIIbeta (显示 PRKAR2B 抗体))-dependent signaling resulting in nuclear redistribution/influx of HDAC4 (histone deacetylase 4 (显示 HDAC5 抗体)) in skeletal muscle fibers.

  6. results are the first to demonstrate that the protective effects of irisin (显示 FNDC5 抗体) in cardiomyoblasts exposed to hypoxia/reoxygenation might be associated with HDAC4 (显示 HDAC5 抗体) degradation.

  7. PC3/Tis21 (显示 BTG2 抗体) associates with HDAC1 (显示 HDAC1 抗体), HDAC4 (显示 HDAC5 抗体), and HDAC9 (显示 HDAC9 抗体) in vivo, in fibroblast cells.

  8. HDAC4 (显示 HDAC5 抗体) increases endogenous SIRT1 (显示 SIRT1 抗体) expression by enhancing its sumoylation modification levels

  9. postmitotic expression SOD1G93A mutant gene promotes a FAPS phenotype in C2C12 cells, by upregulating HDAC4 (显示 HDAC5 抗体) protein and preventing the BAF60C (显示 SMARCD3 抗体)-SWI (显示 SMARCA1 抗体)/SNF (显示 SNRPA 抗体) complex myogenic commitment

  10. miR (显示 MLXIP 抗体)-29a was involved in the regulation of HDAC4 (显示 HDAC5 抗体) and modulation of the profibrogenic phenotype in hepatic stellate cells.

Zebrafish Histone Deacetylase 4 (HDAC4) interaction partners

  1. Results demonstrate that Hdac4 is a regulator of cranial neural crest-derived palatal skeletal precursors during early embryogenesis.

Cow (Bovine) Histone Deacetylase 4 (HDAC4) interaction partners

  1. our results revealed the mechanism in which miR-1 and miR (显示 MYLIP 抗体)-206 positively regulate bovine skeletal muscle satellite cell myogenic differentiation via Pax7 (显示 PAX7 抗体) and HDAC4 downregulation.

HDAC4 抗原简介

Antigen Summary

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.

Alternative names and synonyms associated with HDAC4

  • histone deacetylase 4 (PTRG_03699) 抗体
  • histone deacetylase 4 (PGTG_15512) 抗体
  • CG1770 gene product from transcript CG1770-RG (HDAC4) 抗体
  • DanaGF18710-PA (DanaHDAC4) 抗体
  • histone deacetylase 4 (HDAC4) 抗体
  • histone deacetylase 4 (Hdac4) 抗体
  • histone deacetylase 4 (hdac4) 抗体
  • 4932408F19Rik 抗体
  • AHO3 抗体
  • AI047285 抗体
  • BDMR 抗体
  • CG1770 抗体
  • DanaGF18710 抗体
  • dana_GLEANR_19966 抗体
  • dHDAC4 抗体
  • Dmel\\CG1770 抗体
  • dmHDA405 抗体
  • GC1770 抗体
  • GF18710 抗体
  • HA6116 抗体
  • HD4 抗体
  • HDAC 抗体
  • HDAC-4 抗体
  • HDAC-A 抗体
  • HDAC4 抗体
  • HDAC4a 抗体
  • HDACA 抗体
  • wu:fa96d08 抗体
  • wu:fc56f08 抗体
  • zgc:152701 抗体

Protein level used designations for HDAC4

histone deacetylase 4 , CG1770-PB , CG1770-PD , CG1770-PE , CG1770-PF , CG1770-PG , CG1770-PH , CG1770-PI , CG1770-PJ , HDAC4-PB , HDAC4-PD , HDAC4-PE , HDAC4-PF , HDAC4-PG , HDAC4-PH , HDAC4-PI , HDAC4-PJ , DanaGF18710-PA , DanaHDAC4-PA , GF18710-PA , HDAC4 , HDAC4-PA , histone deacetylase A , HD4

6341931 Pyrenophora tritici-repentis Pt-1C-BFP
10547054 Puccinia graminis f. sp. tritici CRL 75-36-700-3
32278 Drosophila melanogaster
6507946 Drosophila ananassae
9759 Homo sapiens
208727 Mus musculus
363287 Rattus norvegicus
374207 Gallus gallus
568877 Danio rerio
607662 Canis lupus familiaris
517559 Bos taurus
anti-HDAC4 (HDAC4) 抗体 精选生产商