anti-HLA-B (HLA-B) 抗体产品概述

Full name:
anti-Major Histocompatibility Complex, Class I, B 抗体 (HLA-B)
在www.antibodies-online.cn可供126 Major Histocompatibility Complex, Class I, B (HLA-B) 抗体的15不同的供货商。 再加上,我们可以发HLA-B 蛋白 (76)HLA-B 试剂盒 (6)和数多这个蛋白质的别的产品。 总共213 HLA-B产品已列进来了。
列出全部抗体 基因 基因ID UniProt
HLA-B 3106 P01889



最受欢迎的抗anti-HLA-B (HLA-B) 抗体


抗Human HLA-B 抗体:

抗Monkey HLA-B 抗体:

所有可销售的anti-HLA-B 抗体


引用最多的anti-HLA-B 抗体

  1. Human Polyclonal HLA-B Primary Antibody for WB - ABIN1944779 : Little, Parham: The HLA-Bw75 subtype of B15: molecular characterization and comparison with crossreacting antigens. in Tissue antigens 1992 (PubMed)
    Show all 5 references for 1944779

  2. Human Polyclonal HLA-B Primary Antibody for WB - ABIN516466 : Lorente, García, López: Allele-dependent processing pathways generate the endogenous human leukocyte antigen (HLA) class I peptide repertoire in transporters associated with antigen processing (TAP)-deficient cells. in The Journal of biological chemistry 2011 (PubMed)
    Show all 3 references for 516466

  3. Human Polyclonal HLA-B Primary Antibody for IHC, WB - ABIN3021869 : Parham, Lomen, Lawlor, Ways, Holmes, Coppin, Salter, Wan, Ennis: Nature of polymorphism in HLA-A, -B, and -C molecules. in Proceedings of the National Academy of Sciences of the United States of America 1988 (PubMed)
    Show all 2 references for 3021869

  4. Human Polyclonal HLA-B Primary Antibody for FACS, IHC (p) - ABIN652557 : Guild, Strominger: Human and murine class I MHC antigens share conserved serine 335, the site of HLA phosphorylation in vivo. in The Journal of biological chemistry 1984 (PubMed)
    Show all 2 references for 652557

  5. Human Polyclonal HLA-B Primary Antibody for WB - ABIN654636 : Noble, Valdes, Varney, Carlson, Moonsamy, Fear, Lane, Lavant, Rappner, Louey, Concannon, Mychaleckyj, Erlich,: HLA class I and genetic susceptibility to type 1 diabetes: results from the Type 1 Diabetes Genetics Consortium. in Diabetes 2010 (PubMed)


Human Major Histocompatibility Complex, Class I, B (HLA-B) interaction partners

  1. This study demonstrated that the expression of a single human class I MHC molecule, independent of persistent virus infection, influences the extent of sub frequent chronic neuronal injury or repair in the absence of a class II MHC immune response.

  2. The HLA-B*50 allele was associated with conversion to myasthenia gravis generalized disease in patients with pure ocular symptoms at disease onset.

  3. findings demonstrate that gliadins contain epitopes that elicit CD8 (显示 CD8A 抗体)+ T cell responses restricted by HLA class I (显示 MICA 抗体) A*0101 and B*0801 molecules

  4. The HLA-B*42, HLA-C*17, HLA-DPA1*03, and HLA-DPB1*105 genotypes were associated with allergic asthma and the HLA-B*48 genotype with the nonallergic phenotype.

  5. There was no increased risk of rheumatoid arthritis in mothers of children with aspartic acid at position 9 of HLA-B.

  6. HLA-B*15:13 and HLA-B*15:02 are associated with phenytoin-induced severe cutaneous adverse reactions in a Malay population.

  7. The study found a strong association between the presence of HLA-B27 and the diagnosis of axial spondyloarthritis (axSpA) and ankylosing spondylitis (AS), but the HLA-B15 (显示 NDUFB4 抗体) is also significantly associated with all subtypes of the disease, predominantly with peripheral spondyloarthritis (pSpA). Additionally, HLA-DR1 (显示 DR1 抗体) and DR4 (显示 HLADRB4 抗体) were associated in a cohort of patients with SpA (显示 FASL 抗体) from Colombia.

  8. selecting a MICA (显示 MICA 抗体)-matched donor significantly influences key clinical outcomes of HCT in which a marked reduction of GVHD is paramount. The tight linkage disequilibrium between MICA (显示 MICA 抗体) and HLA-B renders identifying a MICA (显示 MICA 抗体)-matched donor readily feasible in clinical practice.

  9. HLA-B51 is a primary association marker in predisposition to Behcet disease, with IL-23R and IL12A being the additional strongest loci.

  10. Here we define the nature and extent of the variation in 3,489 HLA-A, 4,356 HLA-B and 3,111 HLA-C alleles. The common alleles of human populations comprise 42 core alleles, which represent all selected polymorphism, and recombinants that have assorted this polymorphism

HLA-B 抗原简介

Antigen Summary

HLA-B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exon 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-B alleles have been described.

Alternative names and synonyms associated with HLA-B

  • major histocompatibility complex, class I, B (BOLA-B) 抗体
  • major histocompatibility complex, class I, B (MAMU-B18) 抗体
  • major histocompatibility complex, class I, B (DKFZP469N1225) 抗体
  • major histocompatibility complex, class I, B (HLA-B) 抗体
  • AS 抗体
  • HLAB 抗体
  • SPDA1 抗体

Protein level used designations for HLA-B

major histocompatibility complex, class I, B , HLA class I histocompatibility antigen, B alpha chain , MHC Class I HLA heavy chain , MHC HLA-B cell surface glycoprotein , MHC HLA-B transmembrane glycoprotein , MHC class I antigen GN00104 , MHC class I antigen HLA-B heavy chain , MHC class I antigen SHCHA , leukocyte antigen class I-B , lymphocyte antigen

282156 Bos taurus
100141394 Macaca mulatta
100173276 Pongo abelii
3106 Homo sapiens
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