anti-APOE (APOE) 抗体产品概述

Full name:
anti-Apolipoprotein E 抗体 (APOE)
在www.antibodies-online.cn可供354 Apolipoprotein E (APOE) 抗体的31不同的供货商。 再加上,我们可以发APOE 试剂盒 (120)APOE 蛋白 (52)和数多这个蛋白质的别的产品。 总共539 APOE产品已列进来了。
别名:
AD2, AI255918, Apo-E, apoe, APOEA, apoprotein, im:7036787, LDLCQ5, LPG, wu:fb69a05, zgc:110064

所有可销售的anti-APOE 抗体

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引用最多的anti-APOE 抗体

  1. Human Monoclonal APOE Primary Antibody for CyTOF, ELISA - ABIN258785 : Wahrle, Jiang, Parsadanian, Hartman, Bales, Paul, Holtzman: Deletion of Abca1 increases Abeta deposition in the PDAPP transgenic mouse model of Alzheimer disease. in The Journal of biological chemistry 2005 (PubMed)
    Show all 10 references for 258785

  2. Human Polyclonal APOE Primary Antibody for IHC, WB - ABIN2774066 : Ho, Niti, Yap, Kua, Ng: Metabolic syndrome and cognitive decline in chinese older adults: results from the singapore longitudinal ageing studies. in The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2008 (PubMed)
    Show all 4 references for 2774066

  3. Human Monoclonal APOE Primary Antibody for EIA, IHC (fro) - ABIN1105420 : Dergunov, Shuvaev, Yanushevskaja: Quaternary structure of apolipoprotein E in solution: fluorimetric, chromatographic and immunochemical studies. in Biological chemistry Hoppe-Seyler 1992 (PubMed)
    Show all 2 references for 1105420

  4. Human Polyclonal APOE Primary Antibody for IHC (p), ELISA - ABIN1997537 : Li, Jiang, Qu, Yao, Cai, Chen, Peng: Hepatocyte nuclear factor 4? and downstream secreted phospholipase A2 GXIIB regulate production of infectious hepatitis C virus. in Journal of virology 2013 (PubMed)
    Show all 2 references for 1997537

  5. Human Polyclonal APOE Primary Antibody for IHC, ELISA - ABIN185375 : Dodart, Marr, Koistinaho, Gregersen, Malkani, Verma, Paul: Gene delivery of human apolipoprotein E alters brain Abeta burden in a mouse model of Alzheimer's disease. in Proceedings of the National Academy of Sciences of the United States of America 2005 (PubMed)
    Show all 2 references for 185375

  6. Human Polyclonal APOE Primary Antibody for IHC (p), WB - ABIN391849 : Benga, Krieger, Dimitrova, Zeisel, Parnot, Lupberger, Hildt, Luo, McLauchlan, Baumert, Schuster: Apolipoprotein E interacts with hepatitis C virus nonstructural protein 5A and determines assembly of infectious particles. in Hepatology (Baltimore, Md.) 2009 (PubMed)

  7. Human Polyclonal APOE Primary Antibody for IF (p), IHC (p) - ABIN1386767 : Liu, Gao, Hao, Lou, Zhang, Li, Wu, Xiao, Yang, Li, Qiu, Wang: Secretomes are a potential source of molecular targets for cancer therapies and indicate that APOE is a candidate biomarker for lung adenocarcinoma metastasis. in Molecular biology reports 2014 (PubMed)

  8. Mouse (Murine) Polyclonal APOE Primary Antibody for IF (p), IHC (p) - ABIN725750 : Chiu, Chan, Yang, Liu, Chiang: Supplementation of Chitosan Alleviates High-Fat Diet-Enhanced Lipogenesis in Rats via Adenosine Monophosphate (AMP)-Activated Protein Kinase Activation and Inhibition of Lipogenesis-Associated Genes. in Journal of agricultural and food chemistry 2015 (PubMed)

更多抗APOE的相互作用对抗体

Mouse (Murine) Apolipoprotein E (APOE) interaction partners

  1. treatment of APP/E4/Abca1+/- mice with liver X receptor (LXR) agonist T0 ameliorates APOE4-induced Alzheimer's disease (AD)-like pathology and therefore targeting the LXR-ABCA1-APOE regulatory axis could be effective as a potential therapeutic approach in AD patients, carriers of APOEepsilon4

  2. Adiponectin (显示 ADIPOQ 抗体), TNF-alpha (显示 TNF 抗体), and LOX-1 (显示 OLR1 抗体) exert complex regulatory effects on the coronary microvascular endothelial function in atherosclerotic ApoE knockout mice.

  3. Apoe-deficient mice and human apoE isoform knockin mice, as well as hypomorphic Apoe mice, have significantly contributed to our understanding of the role of apoE in lipoprotein metabolism. [review]

  4. beta-Sarcoglycan (显示 SGCB 抗体) deficiency reduces atherosclerotic plaque formation in ApoE-knockout mouse model.

  5. we found that the lack of microbiota caused a significant reduction in atherosclerotic lesion formation compared with Conv ApoE(-/-) mice, which might be associated with the attenuation of lipopolysaccharide-mediated inflammatory responses. Our findings indicated that the gut (显示 GUSB 抗体) microbiota affected both hypercholesterolemia and atherogenesis in mice

  6. this reduction in lesion formation was associated with reduced numbers of lesional SMCs but not macrophages within the transplanted Cx3cr-/- Apoe-/- aortic segment. No differences in frequencies of proliferating and apoptotic cells could be observed. These results indicate that CX3CR1 (显示 CX3CR1 抗体) on resident vessel wall cells plays a key role in atherosclerotic plaque formation in transplanted aortic grafts

  7. Specific inhibition of the NLRP3 (显示 NLRP3 抗体) inflammasome using MCC950 can be a promising therapeutic approach to inhibit atherosclerotic lesion development in ApoE deficient mice.

  8. catK (显示 CTSK 抗体) deficiency almost completely blunted the increased vascular remodeling response of apoE-/- mice to flow cessation, possibly by correcting hyperlipidemia-associated pro-inflammatory effects on the peripheral immune response

  9. High fat intake inhibits the compensatory mechanisms of neuroinflammation and neurogenesis in aged female ApoE4 and ApoE-/- mice.

  10. The levels of EZH2 (显示 EZH2 抗体) and H3K27me3 were increased in the aorta of ApoE-/- mice fed a high-methionine diet for 16 weeks, whereas miR (显示 MLXIP 抗体)-92a expression was decreased.

Human Apolipoprotein E (APOE) interaction partners

  1. the identification of the e4 allele of Apolipoprotein E as a strong genetic risk factor for both early-onset and late-onset Alzheimer disease (AD) , and evolved to the more recent detection of at least 21 additional genetic risk loci for the genetically complex form of AD emerging from genome-wide association studies

  2. APOE-epsilon2 allele was more frequent in ALS patients than in controls.

  3. Study analyzed 595 older adults without dementia classified cross-sectionally as Abeta (显示 APP 抗体)- and Abeta (显示 APP 抗体)+ using longitudinal florbetapir positron emission tomography. APOE epsilon4 carriage and older age were predictors of longitudinal Abeta (显示 APP 抗体) accumulation within the Abeta (显示 APP 抗体)- group but not the Abeta (显示 APP 抗体)+ group. APOE epsilon2 carriage was protective against longitudinal Abeta (显示 APP 抗体) accumulation within the Abeta (显示 APP 抗体)- group.

  4. Meta-analysis suggested that there is no association between APOE polymorphism and subarachnoid hemorrhage risk for overall population. Increased risk of SAH (显示 ACSM3 抗体) was found in Asian subjects when epsilon4 allele compared with epsilon3 allele.

  5. Here, we have shown that genetic restoration of plasma ApoE to wild-type levels normalizes plasma lipids in ApoE KO mice. While this does not rescue synaptic loss, it does completely restore learning and memory in the mice, suggesting that both CNS and plasma ApoE are independent parameters that affect brain health.

  6. the results of current study found a significant gene- gene interaction between rs405509 of APOE gene polymorphism and rs1805192 of PPARG (显示 PPARG 抗体) polymorphism associated with increased Late-Onset Alzheimer's Disease risk

  7. ApoE epsilon4 allele seems to be risk factor for major adverse cardiovascular events, and in particular for total peripheral revascularization in patients with advanced atherosclerotic vascular disease.

  8. Data suggest that the redox status of serum apoE might be related to the synthesis of HDL (显示 HSD11B1 抗体); the cysteine-thiol residue of reduced-apoE is in a naive state, while that of non-reduced-apoE is in a reversibly or irreversibly oxidized state. Data suggest that apoE homodimer and apoE-AII (显示 NLRP3 抗体) complex are typical reversibly oxidized forms of apoE. (apoE-AII (显示 NLRP3 抗体) complex = a complex of apolipoprotein E and apolipoprotein A-II (显示 APOA2 抗体))

  9. carriers of the ApoE varepsilon4 polymorphism genotype show demonstrable improvement in VA after treatment with ranibizumab in exudative AMD (显示 AMD1 抗体).

  10. Findings do not provide significant support for presenilin 1 (PSEN1 (显示 PSEN1 抗体)) E318G as a risk factor for Alzheimer's disease (AD) in apolipoprotein E4 (APOEepsilon4) carriers.

Rabbit Apolipoprotein E (APOE) interaction partners

  1. we report the efficient creation of an APOE knockout rabbit by using zinc finger nucleases. The knockout rabbits had drastically elevated cholesterol and moderately increased triglyceride levels, mimicking symptoms in human heart disease.

  2. The molar ratio ApoE/ApoA-I (显示 APOA1 抗体) is negatively correlated with the enzyme activity, and positively correlated with increases in the intima-media thickness of common carotid wall and cardiac dysfunction signs.

  3. ApoE mimetic peptide reduces plasma lipid hydroperoxide content with a concomitant increase in HDL (显示 HSD11B1 抗体) paraoxonase activity

  4. The identification of disulphide-linked apoE dimers in cortical and hippocampal tissues represents a distinct structural difference between the apoE3 and apoE4 isoforms that may have functional consequences.

Pig (Porcine) Apolipoprotein E (APOE) interaction partners

  1. These data suggest that the -155T>A mutation in the promoter region of the porcine APOE gene is an important functional variant

Cow (Bovine) Apolipoprotein E (APOE) interaction partners

  1. Nonesterified fatty acids significantly inhibit the expression of ApoB100 (显示 APOB 抗体), ApoE, MTP (显示 MTTP 抗体), and LDLR (显示 LDLR 抗体), thereby decreasing the synthesis and assembly of VLDL and inducing TG accumulation in bovine hepatocytes.

  2. Bovine apoE contents in triglyceride-rich lipoproteins are modulated by nutritional treatment and closely associated with triglyceride-rich lipoprotein metabolism

  3. apoE-containing particles, which increased during the lactating stage, were not associated with HDL (显示 HSD11B1 抗体) particles, and lipid-free forms were included in cow plasma

  4. after calving the apolipoprotein B(100 (显示 APOB 抗体)) mRNA synthesis was lower, whereas microsomal triglyceride transfer protein (MTP (显示 MTTP 抗体)) and apolipoprotein E messenger RNA abundance were higher in the liver

Chimpanzee Apolipoprotein E (APOE) interaction partners

  1. The study found no coding variation within and between chimpanzee populations, suggesting that the maintenance of functionally diverse APOE polymorphisms is a unique feature of human evolution.

  2. ApoE evolution and very likely the evolution of other apolipoproteins are influenced by feeding environment and diet of humans, chimpanzees and various other species.

Rhesus Monkey Apolipoprotein E (APOE) interaction partners

  1. In the hippocampus APOE protein levels were higher in good spatial performers than poor spatial performers animals

  2. Allele frequencies of the ApoE gene found show that allele epsilon3 has one of the highest frequencies and epsilon4 allele one of the lowest compared to other population groups in the world

  3. There was significantly more apoE immunoreactivity in the prefrontal cortex and hippocampus of aged animals compared to adult or middle-aged animals.

APOE 抗原简介

Antigen Summary

Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.

Alternative names and synonyms associated with APOE

  • apolipoprotein E (apoe) 抗体
  • apolipoprotein Ea (apoea) 抗体
  • apolipoprotein E (Apoe) 抗体
  • apolipoprotein E (APOE) 抗体
  • AD2 抗体
  • AI255918 抗体
  • Apo-E 抗体
  • apoe 抗体
  • APOEA 抗体
  • apoprotein 抗体
  • im:7036787 抗体
  • LDLCQ5 抗体
  • LPG 抗体
  • wu:fb69a05 抗体
  • zgc:110064 抗体

Protein level used designations for anti-Apolipoprotein E (APOE) 抗体

apolipoprotein E , ApoE-1 , apo-E , apolipoprotein E3

GENE ID SPECIES
394678 Xenopus (Silurana) tropicalis
553587 Danio rerio
100136023 Oncorhynchus mykiss
100380959 Xenopus laevis
11816 Mus musculus
348 Homo sapiens
100009337 Oryctolagus cuniculus
25728 Rattus norvegicus
397576 Sus scrofa
100731633 Cavia porcellus
281004 Bos taurus
476438 Canis lupus familiaris
449586 Pan troglodytes
714623 Macaca mulatta
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