anti-p300 (EP300) 抗体产品概述

在www.antibodies-online.cn可供273 E1A Binding Protein P300 (EP300) 抗体的22不同的供货商。 再加上,我们可以发p300 试剂盒 (16)p300 蛋白 (9)和数多这个蛋白质的别的产品。 总共314 p300产品已列进来了。
别名:
A430090G16, A730011L11, KAT3B, p300, p300 HAT, RSTS2
列出全部抗体 基因 基因ID UniProt
EP300 2033 Q09472
EP300 328572  
EP300 170915  

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更多抗p300的相互作用对抗体

Human E1A Binding Protein P300 (EP300) interaction partners

  1. our findings identify the TXN (显示 TXN 抗体)-FOXO1 (显示 FOXO1 抗体)-p300 circuit as the sensor and effector of oxidative stress in DLBCL cells

  2. Acetylation-dependent control of global poly(A) RNA degradation by CBP/p300 (显示 CREBBP 抗体) and HDAC1-HDAC2 (显示 HDAC1 抗体) has been described.

  3. Although TP53 (显示 TP53 抗体) and BAX (显示 BAX 抗体) immunoreactivity levels were associated with some clinicopathological parameters of the patients, the expression of EP300, TP53 (显示 TP53 抗体) and BAX (显示 BAX 抗体) did not reveal any prognostic significance in ccRCC

  4. 5-FU promotes global histone de-acetylation by enhancing the degradation of p300/CBP (显示 CREBBP 抗体) in colorectal neoplasms.

  5. ELF3 (显示 ELF3 抗体) interacts directly with the HMG (显示 SSRP1 抗体) domain of Sox9 (显示 SOX9 抗体). Importantly, overexpression of ELF3 (显示 ELF3 抗体) significantly decreased Sox9 (显示 SOX9 抗体)/CBP (显示 CREBBP 抗体)-dependent HAT (显示 MGEA5 抗体) activity.

  6. CTPB promoted the survival and neurite growth of the SH-SY5Y cells, and also protected these cells from cell death induced by the neurotoxin 6-hydroxydopamine. This study is the first to investigate the phenotypic effects of the HAT (显示 MGEA5 抗体) activator CTPB, and to demonstrate that p300/CBP (显示 CREBBP 抗体) HAT (显示 MGEA5 抗体) activation has neurotrophic effects in a cellular model of Parkinson's Disease.

  7. c-Jun (显示 JUN 抗体) and p300 are novel interacting partners of AEG-1 (显示 MTDH 抗体) in gliomas.

  8. 2-O, 3-O desulfated heparin inhibited HMGB1 (显示 HMGB1 抗体) release, at least in part, by direct molecular inhibition of p300 HAT activity.

  9. Shikonin induces apoptosis in some lung cancer cells via activation of FOXO3a (显示 FOXO3 抗体)/EGR1 (显示 EGR1 抗体)/SIRT1 (显示 SIRT1 抗体) signaling, and AKT (显示 AKT1 抗体) and p300 negatively regulate this process via Bim (显示 BCL2L11 抗体) upregulation.

  10. A potential mechanism for the role of Sirt1 (显示 SIRT1 抗体) in lung fibrosis was through regulating the expression of p300. Thus, we characterized Sirt1 (显示 SIRT1 抗体) as an important regulator of lung fibrosis and provides a proof of principle for activation or overexpression of Sirt1 (显示 SIRT1 抗体) as a potential novel therapeutic strategy for IPF.

Mouse (Murine) E1A Binding Protein P300 (EP300) interaction partners

  1. Acetylation-dependent control of global poly(A) RNA degradation by CBP/p300 (显示 CREBBP 抗体) and HDAC1-HDAC2 (显示 HDAC1 抗体) has been described.

  2. Data, including data from studies in cells from knockout mice, suggest that Prmt1 (显示 PRMT1 抗体) activity was necessary for c-Myc (显示 MYC 抗体) binding to acetyltransferase p300 (显示 NOTCH1 抗体) in myeloid cells; Prmt1 (显示 PRMT1 抗体) inhibition decreases p300 (显示 NOTCH1 抗体) recruitment to c-Myc (显示 MYC 抗体) target promoters and increased Hdac1 (显示 HDAC1 抗体) recruitment. [Prmt1 (显示 PRMT1 抗体), protein arginine N-methyltransferase 1 (显示 PRMT1 抗体); c-Myc (显示 MYC 抗体) = Proto-Oncogene (显示 RAB1A 抗体) Proteins c-myc (显示 MYC 抗体); Hdac1 (显示 HDAC1 抗体) = histone deacetylase 1 (显示 HDAC1 抗体)]

  3. In line with the acetyltransferase activity of p300 (显示 NOTCH1 抗体), H3K27 acetylation was reduced after HDACi and resulted in the formation of heterochromatin in the PTGES1 gene. In conclusion, HDAC (显示 HDAC3 抗体) activity maintains PTGES1 expression by recruiting p300 (显示 NOTCH1 抗体) to its gene

  4. ARX positively regulates Wnt (显示 WNT2 抗体)/ beta-catenin (显示 CTNNB1 抗体) signaling and the C-terminal domain of ARX interacts with the armadillo (显示 PKP1 抗体) repeats in beta-catenin (显示 CTNNB1 抗体) to promote Wnt (显示 WNT2 抗体)/beta-catenin (显示 CTNNB1 抗体) signaling. In addition, we found BCL9 (显示 BCL9 抗体) and P300 (显示 NOTCH1 抗体) also interact with ARX to modulate Wnt (显示 WNT2 抗体)/beta-catenin (显示 CTNNB1 抗体) signaling.

  5. 2-O, 3-O desulfated heparin inhibited HMGB1 (显示 HMGB1 抗体) release, at least in part, by direct molecular inhibition of p300 HAT activity.

  6. work shows that helenalin acetate inhibits C/EBPbeta (显示 CEBPB 抗体) by binding to the N-terminal part of C/EBPbeta (显示 CEBPB 抗体), thereby disrupting the cooperation of C/EBPbeta (显示 CEBPB 抗体) with the co-activator p300 (显示 NOTCH1 抗体).

  7. STAT6 (显示 STAT6 抗体) mediates the CT-induced TIM4 (显示 TIMD4 抗体) expression in DCs. In conclusion, p300 (显示 NOTCH1 抗体) and STAT6 (显示 STAT6 抗体) mediate the microbial product CT-induced TIM4 (显示 TIMD4 抗体) expression in DCs.

  8. Findings indicate that E1a-binding protein (p300) is not required for the normal development or functioning of skeletal muscle.

  9. Hdac3 (显示 HDAC3 抗体) cooperates with p300 (显示 NOTCH1 抗体) to prime and maintain oligodendrocyte identity

  10. p300 (显示 NOTCH1 抗体) histone acetyltransferase (显示 HAT 抗体) activity is critical for Wnt (显示 WNT2 抗体)-dependent palate mesenchymal cell proliferation and migration, both processes that play a significant role in morphogenesis of the palate.

p300 (EP300) 抗原简介

Antigen Summary

This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer.

Alternative names and synonyms associated with p300 (EP300)

  • E1A binding protein p300 (EP300) 抗体
  • E1A-associated protein p300 (ep300) 抗体
  • E1A binding protein p300 (ep300) 抗体
  • E1A binding protein p300 (Ep300) 抗体
  • A430090G16 抗体
  • A730011L11 抗体
  • KAT3B 抗体
  • p300 抗体
  • p300 HAT 抗体
  • RSTS2 抗体

Protein level used designations for EP300

histone acetyltransferase p300 , histone acetyltransferase , E1A binding protein p300 , histone acetyltransferase p300-like , E1A-associated protein p300 , E1A-binding protein, 300kD , p300 HAT

GENE ID SPECIES
100055626 Equus caballus
458862 Pan troglodytes
706258 Macaca mulatta
446056 Takifugu rubripes
100028102 Monodelphis domestica
100455260 Pongo abelii
100468694 Ailuropoda melanoleuca
100543704 Meleagris gallopavo
100566746 Anolis carolinensis
2033 Homo sapiens
328572 Mus musculus
418000 Gallus gallus
100684945 Canis lupus familiaris
100156226 Sus scrofa
170915 Rattus norvegicus
100734820 Cavia porcellus
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