anti-RORC (RORC) 抗体产品概述

Full name:
anti-RAR-Related Orphan Receptor C 抗体 (RORC)
在www.antibodies-online.cn可供167 RAR-Related Orphan Receptor C (RORC) 抗体的24不同的供货商。 再加上,我们可以发RORC 试剂盒 (20)RORC 蛋白 (12)和数多这个蛋白质的别的产品。 总共217 RORC产品已列进来了。
别名:
Nr1f3, RORG, RORgamma, RZR-GAMMA, RZRG, Thor, TOR

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引用最多的anti-RORC 抗体

  1. Human Polyclonal RORC Primary Antibody for ELISA, IHC (p) - ABIN271147 : Tosolini, Kirilovsky, Mlecnik, Fredriksen, Mauger, Bindea, Berger, Bruneval, Fridman, Pagès, Galon: Clinical impact of different classes of infiltrating T cytotoxic and helper cells (Th1, th2, treg, th17) in patients with colorectal cancer. in Cancer research 2011 (PubMed)
    Show all 2 references for 271147

  2. Cow (Bovine) Polyclonal RORC Primary Antibody for IHC, WB - ABIN2782284 : Huang, Xie, Wang, Sun: Retinoid-related orphan receptor gamma t is a potential therapeutic target for controlling inflammatory autoimmunity. in Expert opinion on therapeutic targets 2007 (PubMed)
    Show all 2 references for 2782284

  3. Cow (Bovine) Polyclonal RORC Primary Antibody for WB - ABIN2777822 : Huang, Huang, Lee, Ng, Chang: Postirradiation sinus mucosa disease in nasopharyngeal carcinoma patients. in The Laryngoscope 2007 (PubMed)
    Show all 2 references for 2777822

  4. Human Monoclonal RORC Primary Antibody for FACS - ABIN4895237 : Wongkajornsilp, Wamanuttajinda, Kasetsinsombat, Duangsa-ard, Sa-ngiamsuntorn, Hongeng, Maneechotesuwan: Sunitinib indirectly enhanced anti-tumor cytotoxicity of cytokine-induced killer cells and CD3⁺CD56⁺ subset through the co-culturing dendritic cells. in PLoS ONE 2013 (PubMed)

  5. Human Monoclonal RORC Primary Antibody for FACS - ABIN4895229 : Verma, Dempsey, Long, Davies, Barry, Fallon, Volkov, Kelleher: Leukocyte function-associated antigen-1/intercellular adhesion molecule-1 interaction induces a novel genetic signature resulting in T-cells refractory to transforming growth factor-β signaling. in The Journal of biological chemistry 2012 (PubMed)

  6. Cow (Bovine) Polyclonal RORC Primary Antibody for WB - ABIN2777823 : Wang, Chu, Das, Zheng, Hasstedt, Elbein: Molecular screening and association studies of retinoid-related orphan receptor gamma (RORC): a positional and functional candidate for type 2 diabetes. in Molecular genetics and metabolism 2003 (PubMed)

  7. Human Monoclonal RORC Primary Antibody for FACS - ABIN4895233 : Zielinski, Mele, Aschenbrenner, Jarrossay, Ronchi, Gattorno, Monticelli, Lanzavecchia, Sallusto: Pathogen-induced human TH17 cells produce IFN-γ or IL-10 and are regulated by IL-1β. in Nature 2012 (PubMed)

更多抗RORC的相互作用对抗体

Human RAR-Related Orphan Receptor C (RORC) interaction partners

  1. There are 2 putative binding motifs for specificity protein transcription factors from the specificity protein/Kruppel-like factor family in the promoter of human RORgammaT. SP2 recognized binding motifs in the human RORgammaT promoter, which was critical for maintaining expression.

  2. Results from the study establish RORgamma as a key player in castration-resistant prostate cancer (CRPCa) by acting upstream of AR and as a new therapeutic target for advanced PCa (显示 FLVCR1 抗体).

  3. Data suggest that apo (显示 C9orf3 抗体) RORC adopts active conformation capable of recruiting coactivator peptides that stabilize helix 12 of the active state in the absence of a ligand; ligand-bound RORC binds inverse agonists that disrupt critical interactions that stabilize helix 12; helix 12 destabilization in the active state shifts the conformational equilibrium of RORC toward an inactive state.

  4. Retinoid-related orphan receptor (显示 NR1D2 抗体) gammat may be associated with NK22 cells in reproduction. Particularly, higher expression of retinoid-related orphan receptor (显示 NR1D2 抗体) gammat may be associated with elevated NK22 cells in unexplained recurrent pregnancy loss.

  5. MiR-16 (显示 GDE1 抗体) may be involved in Th17/Treg imbalance in rheumatoid arthritis patients by affecting the expression of RORgt and FoxP3 (显示 FOXP3 抗体).

  6. Serum RORC levels was higher in rheumatoid arthritis (RA) patients with rs9826AA, rs12045886TT and -TC, and rs9017AA genotypes compared to healthy subjects with the same genotypes (p = 0.02, p = 0.04 and p = 0.01, respectively).

  7. The findings suggest that RORC plays a significant role in the dysregulated immune response associated with lupus erythematosus (SLE) .

  8. RORgammat is acetylated, and this acetylation is reciprocally regulated by the histone acetyltransferase p300 (显示 EP300 抗体) and the histone deacetylase HDAC1 (显示 HDAC1 抗体).

  9. A high copy number of T-bet and GATA-3 (显示 GATA3 抗体) confers susceptibility to AAU and AS, and a high copy number of FOXP3 (显示 FOXP3 抗体) confers susceptibility to female patients with AAU either with or without AS.

  10. melatonin suppresses HIF-1alpha (显示 HIF1A 抗体) accumulation and VEGF (显示 VEGFA 抗体) generation via inhibition of melatonin nuclear receptor RZR/RORgamma in SGC (显示 SGCB 抗体)-7901 cells under hypoxia.

Cow (Bovine) RAR-Related Orphan Receptor C (RORC) interaction partners

  1. The total frequencies for the combined genotypes for the bGH and RORC genes, which provide for superior meat quality and carcass weight, in the populations of Kazakh white-headed cattle

  2. The role of the orphan receptor (显示 NR1D2 抗体) C allele variation on intramuscular fat in beef cattle is reported.

Mouse (Murine) RAR-Related Orphan Receptor C (RORC) interaction partners

  1. ubiquitination of K446 limits RORgammat-mediated Th17 differentiation by inhibiting the recruitment of coactivator SRC1 (显示 NCOA1 抗体)

  2. RORgamma/IL-17A (显示 IL17A 抗体) axis influences VEGF (显示 VEGFA 抗体) production and neovascular retinopathy by mechanisms involving neuroglia. Inhibition of RORgamma and IL-17A (显示 IL17A 抗体) may have potential for the improved treatment of neovascular retinopathies.

  3. secretion of IL-17 (显示 IL17A 抗体) by biTregs was abrogated completely in FoxP3 (显示 FOXP3 抗体)(Cre) x RORC(fl/fl (显示 FLT3LG 抗体)) mice. Furthermore, Tregs showed a more activated phenotype after cell-specific inactivation of RORgammat signalling. Finally, and remarkably, biTregs were found to potently suppress anti-inflammatory Th2 immunity in a RORgammat-dependent manner.

  4. this study reveales a new mechanism through which procyanidin B2 gallates inhibit IFN-gamma and IL-17 production in T cells by down-regulation of T-bet and RORgammat expression

  5. The data suggest that RORgt expression in Tregs contributes to an optimal suppressive capacity during gut (显示 GUSB 抗体)-specific immune responses, rendering Foxp3 (显示 FOXP3 抗体)-RORgt T cells as an important effector Treg subset in the intestinal system.

  6. Rag-RORgammat-reporter and Rag KO mice undergoing ischemia reperfusion injury expressed high protein levels of both IL-22 (显示 IL22 抗体) and GFP (RORgammat)

  7. Epidermal Notch1 (显示 NOTCH1 抗体) recruits RORgamma(+) group 3 innate lymphoid cells to orchestrate normal skin repair.

  8. injected chlorhexidine gluconate into wild-type, T-bet Tg, GATA-3 (显示 GATA3 抗体) Tg, and RORgammat Tg mice and analyzed body weight on day 21

  9. Dysregulated development of IL-17 (显示 IL17A 抗体)- and IL-21 (显示 IL21 抗体)-expressing follicular helper T cells and increased germinal center formation in the absence of RORgammat.

  10. BET bromodomains are involved in psoriasis-like inflammation through induction of RORC/IL-17A (显示 IL17A 抗体) pathway.

RORC 抗原简介

Antigen Summary

The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known\; however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with RORC

  • RAR-related orphan receptor C (RORC) 抗体
  • RAR-related orphan receptor C (Rorc) 抗体
  • RAR-related orphan receptor gamma (Rorc) 抗体
  • Nr1f3 抗体
  • RORG 抗体
  • RORgamma 抗体
  • RZR-GAMMA 抗体
  • RZRG 抗体
  • Thor 抗体
  • TOR 抗体

Protein level used designations for RORC

RAR-related orphan nuclear receptor variant 2 , nuclear receptor ROR-gamma , nuclear receptor RZR-gamma , nuclear receptor subfamily 1 group F member 3 , retinoic acid-binding receptor gamma , retinoid-related orphan receptor gamma , RAR-related orphan receptor gamma , retinoid-related orphan receptor-gamma , thymus orphan receptor

GENE ID SPECIES
6097 Homo sapiens
483205 Canis lupus familiaris
527470 Bos taurus
368158 Rattus norvegicus
19885 Mus musculus
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