anti-F2R (F2R) 抗体产品概述

Full name:
anti-Coagulation Factor II (thrombin) Receptor 抗体 (F2R)
在www.antibodies-online.cn可供186 Coagulation Factor II (thrombin) Receptor (F2R) 抗体的26不同的供货商。 再加上,我们可以发F2R 试剂盒 (65)F2R 蛋白 (5)和数多这个蛋白质的别的产品。 总共272 F2R产品已列进来了。
别名:
AI482343, BXR, Cf2r, f2r-a, HTR, ONR1, PAR, Par-1, Par1, PAR2, PARq, PRR, PXR, SAR, SXR, ThrR, TR, TRGPC

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引用最多的anti-F2R 抗体

  1. Human Monoclonal F2R Primary Antibody for IF, WB - ABIN968573 : Coughlin: How the protease thrombin talks to cells. in Proceedings of the National Academy of Sciences of the United States of America 1999 (PubMed)
    Show all 4 references for 968573

  2. Human Polyclonal F2R Primary Antibody for IF (p), IHC (p) - ABIN728743 : Liu, Xie, Luo, Chen, Zhou, Xia, Chen, Zhou, Cao, Cao, Zhou: Identification of FLOT2 as a novel target for microRNA-34a in melanoma. in Journal of cancer research and clinical oncology 2014 (PubMed)
    Show all 3 references for 728743

  3. Human Polyclonal F2R Primary Antibody for WB - ABIN611146 : Gradin, Larsson, Marklund, Gullberg: Regulation of microtubule dynamics by extracellular signals: cAMP-dependent protein kinase switches off the activity of oncoprotein 18 in intact cells. in The Journal of cell biology 1998 (PubMed)
    Show all 3 references for 611146

  4. Human Polyclonal F2R Primary Antibody for ICC, IF - ABIN1742019 : Ossovskaya, Bunnett: Protease-activated receptors: contribution to physiology and disease. in Physiological reviews 2004 (PubMed)

  5. Human Monoclonal F2R Primary Antibody for FACS - ABIN4897018 : Hagag, Nosair, Ghaith, Elshenawy: Prognostic value of protease activated receptor-1 in children with acute lymphoblastic leukemia. in Mediterranean journal of hematology and infectious diseases 2014 (PubMed)

  6. Guinea Pig Polyclonal F2R Primary Antibody for WB - ABIN2784606 : Kamio, Hashizume, Nakao, Matsushima, Sugiya: Plasmin is involved in inflammation via protease-activated receptor-1 activation in human dental pulp. in Biochemical pharmacology 2008 (PubMed)

  7. Human Polyclonal F2R Primary Antibody for ELISA, WB - ABIN1533416 : Vu, Hung, Wheaton, Coughlin: Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. in Cell 1991 (PubMed)

更多抗F2R的相互作用对抗体

Human Coagulation Factor II (thrombin) Receptor (F2R) interaction partners

  1. In intrahepatic cholestasis of pregnancy, gene silencing of miR (显示 MLXIP 抗体)-148a upregulated PXR (显示 NR1I2 抗体) expression which was inhibited by estradiol in liver cells. miR (显示 MLXIP 抗体)-148a may be involved in the estrogen induction in ICP via PXR (显示 NR1I2 抗体) signaling. MRP3 (显示 ABCC3 抗体) may be involved.

  2. Data suggest that the abrogation of protease-activated receptor 1 (PAR1)-dependent signaling pathways may prove a promising strategy for gliomas.

  3. these data indicate that KLKB1 (显示 KLKB1 抗体) induces inflammatory reactions in human dental tissues via protease-activated receptor 1

  4. In this study, we found upregulation of several hemostasis-related genes, including the thrombin (显示 F2 抗体)-activatable receptor PAR-1 (protease-activated receptor-1), in Runx1 (显示 RUNX1 抗体)/Cbfb (显示 CBFB 抗体)-deleted MLL (显示 MLL 抗体)-AF9 (显示 MLLT3 抗体) cells. Similar to the effect of Runx1 (显示 RUNX1 抗体)/Cbfb (显示 CBFB 抗体) deletion, PAR-1 (显示 MARK2 抗体) overexpression induced CDKN1A/p21 (显示 CDKN1A 抗体) expression and attenuated proliferation in MLL (显示 MLL 抗体)-AF9 (显示 MLLT3 抗体) cells

  5. this study shows that PXR (显示 NR1I2 抗体) augments Mycobacterium tuberculosis survival inside the host macrophages by promoting the foamy macrophage formation and abrogating phagolysosomal fusion, inflammation, and apoptosis

  6. PXR (显示 NR1I2 抗体) is a potential biomarker for predicting outcome and activates MRP3 (显示 ABCC3 抗体) transcription by directly binding to its promoter resulting in an increased L-OHP efflux capacity, and resistance to L-OHP or platinum drugs in CRC (显示 CALR 抗体).

  7. This is the first time an association between NR1I2 (显示 NR1I2 抗体) polymorphism and time of progression to AIDS is reported and supports an apparent relationship between the gene in the immune response and identifies another genetic factor influencing AIDS progression.

  8. Data highlight functional differences in proliferation and barrier integrity between dark keratinocytes and fair keratinocytes that are partly associated with their differential expression of PAR1 (显示 MARK2 抗体) and PAR2 (显示 F2RL1 抗体).

  9. MD simulations further revealed that the presence of small molecule at allosteric site disrupts the LBD dynamics and locks the LBD in a "tightly-contracted" conformation. The molecular details provided here could guide new structural studies to understand PXR (显示 NR1I2 抗体) activation and antagonism.

  10. Extracellular granzyme K (显示 GZMK 抗体) mediates endothelial activation through the cleavage of PAR-1 (显示 MARK2 抗体).

Mouse (Murine) Coagulation Factor II (thrombin) Receptor (F2R) interaction partners

  1. In this study, we found upregulation of several hemostasis-related genes, including the thrombin (显示 F2 抗体)-activatable receptor PAR-1 (protease-activated receptor-1), in Runx1 (显示 RUNX1 抗体)/Cbfb (显示 CBFB 抗体)-deleted MLL (显示 MLL 抗体)-AF9 (显示 MLLT3 抗体) cells. Similar to the effect of Runx1 (显示 RUNX1 抗体)/Cbfb (显示 CBFB 抗体) deletion, PAR-1 (显示 MARK2 抗体) overexpression induced CDKN1A/p21 (显示 CDKN1A 抗体) expression and attenuated proliferation in MLL (显示 MLL 抗体)-AF9 (显示 MLLT3 抗体) cells

  2. our findings define a detrimental role of thrombin (显示 F2 抗体)-activated PAR-1 (显示 MARK2 抗体) in wound healing in mice with spinal cord injuries.

  3. thrombin (显示 F2 抗体)/PAR-1 (显示 MARK2 抗体) interaction regulated MCP-1 (显示 CPT1B 抗体), TF, MCSF (显示 CSF1 抗体) and IL-6 (显示 IL6 抗体) production.

  4. Thrombin (显示 F2 抗体) upregulates LCN2 (显示 LCN2 抗体) through protease-activated receptor-1 activation and causes brain damage.

  5. Matrix metalloproteinases (MMP) are effectors of hippocampal neuroplasticity in the adult central nervous system and that the MMP-1 (显示 MMP1 抗体)/protease-activated receptor-1 axis may play a role in neurogenesis following physiological and/or pathological stimuli.

  6. Data indicate an involvement of protease-activated receptor-1 in the neuroinflammation mediated by Eomes (显示 EOMES 抗体)(+) CD4 (显示 CD4 抗体)(+) T cells.

  7. Bladder PAR (显示 AFG3L2 抗体) activation elicits urothelial MIF (显示 MIF 抗体) release and urothelial MIF (显示 MIF 抗体) receptor signaling at least partly through CXCR4 (显示 CXCR4 抗体) to result in abdominal hypersensitivity without overt bladder inflammation

  8. Data suggest that the pro-fibrotic effects of protease-activated receptor PAR-1 (显示 MARK2 抗体) require the presence of protease-activated receptor PAR-2 (显示 F2RL1 抗体).

  9. Thrombin (显示 F2 抗体)-PAR1 signaling, via nitric oxide and EPCR (显示 PROCR 抗体), promotes hematopoietic stem cell (HSC (显示 FUT1 抗体)) mobilization. aPC (显示 APC 抗体)-EPCR (显示 PROCR 抗体)-PAR1 signaling promotes HSC (显示 FUT1 抗体) retention in bone marrow.

  10. Colonic adenocarcinoma growth was reduced in PAR-1 (显示 MARK2 抗体)-deficient mice. Stromal cell-associated PAR-1 (显示 MARK2 抗体) as one thrombin (显示 F2 抗体) target important for tumor outgrowth.

Cow (Bovine) Coagulation Factor II (thrombin) Receptor (F2R) interaction partners

  1. MMP-1 (显示 MMP1 抗体) promotes VEGFR2 (显示 KDR 抗体) expression and proliferation of endothelial cells through stimulation of PAR-1 and activation of NF-kappaB (显示 NFKB1 抗体)

  2. PAR1 and PAR2 (显示 F2RL1 抗体) regulate endothelial NO synthase (显示 NOS 抗体) phosphorylation and activity through G(12/13) and G(q), delineating the signaling pathways by which the proteases act on protease-activated receptors to modulate endothelial functions.

Pig (Porcine) Coagulation Factor II (thrombin) Receptor (F2R) interaction partners

  1. Thrombin (显示 F2 抗体) stimulates swine smooth muscle cell differentiation from peripheral blood mononuclear cells via protease-activated receptor-1, RhoA (显示 RHOA 抗体), and myocardin (显示 MYOCD 抗体).

  2. Thrombin (显示 F2 抗体) induces a sustained contraction in the normal pulmonary artery, by activating PAR(1) and thereby increasing the sensitivity of the myofilament to Ca(2 (显示 CA2 抗体)+).

F2R 抗原简介

Antigen Summary

This gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG (CUG) translation initiation codon, have been described for this gene. Additional transcript variants exist, however, they have not been fully characterized.

Alternative names and synonyms associated with F2R

  • coagulation factor 2 (thrombin) receptor (f2r) 抗体
  • coagulation factor II (thrombin) receptor (F2R) 抗体
  • coagulation factor II (thrombin) receptor (F2r) 抗体
  • nuclear receptor subfamily 1, group I, member 2 (NR1I2) 抗体
  • AI482343 抗体
  • BXR 抗体
  • Cf2r 抗体
  • f2r-a 抗体
  • HTR 抗体
  • ONR1 抗体
  • PAR 抗体
  • Par-1 抗体
  • Par1 抗体
  • PAR2 抗体
  • PARq 抗体
  • PRR 抗体
  • PXR 抗体
  • SAR 抗体
  • SXR 抗体
  • ThrR 抗体
  • TR 抗体
  • TRGPC 抗体

Protein level used designations for F2R

PAR-1 , coagulation factor II (thrombin) receptor , coagulation factor II receptor , proteinase-activated receptor 1 , thrombin receptor , protease-activated receptor 1 , Thrombin receptor , protease-activated receptor-1 , nuclear receptor subfamily 1 group I member 2 , orphan nuclear receptor PAR1 , orphan nuclear receptor PXR , pregnane X nuclear receptor variant 2 , pregnane X receptor , steroid and xenobiotic receptor

GENE ID SPECIES
378526 Xenopus laevis
2149 Homo sapiens
14062 Mus musculus
25439 Rattus norvegicus
526585 Bos taurus
100521609 Sus scrofa
8856 Homo sapiens
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