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anti-MAP3K7 (MAP3K7) 抗体产品概述

Full name:
anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 抗体 (MAP3K7)
在www.antibodies-online.cn可供183 Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) 抗体的15不同的供货商。 再加上,我们可以发MAP3K7 试剂盒 (10)MAP3K7 蛋白 (6)和数多这个蛋白质的别的产品。 总共218 MAP3K7产品已列进来了。
别名:
B430101B05, C87327, MEKK7, si:ch211-225h9.1, TAK1, TGF1a, zgc:110612

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引用最多的anti-MAP3K7 抗体

  1. Human Polyclonal MAP3K7 Primary Antibody for EIA, IHC (p) - ABIN360354 : Takaesu, Surabhi, Park, Ninomiya-Tsuji, Matsumoto, Gaynor: TAK1 is critical for IkappaB kinase-mediated activation of the NF-kappaB pathway. in Journal of molecular biology 2003 (PubMed)
    Show all 5 references for ABIN360354

  2. Human Polyclonal MAP3K7 Primary Antibody for EIA - ABIN358291 : Ono, Ohtomo, Ninomiya-Tsuji, Tsuchiya: A dominant negative TAK1 inhibits cellular fibrotic responses induced by TGF-beta. in Biochemical and biophysical research communications 2003 (PubMed)
    Show all 5 references for ABIN358291

  3. Human Polyclonal MAP3K7 Primary Antibody for DB, EIA - ABIN358312 : Smit, Baas, Kuipers, Korswagen, van de Wetering, Clevers: Wnt activates the Tak1/Nemo-like kinase pathway. in The Journal of biological chemistry 2004 (PubMed)
    Show all 5 references for ABIN358312

  4. Human Polyclonal MAP3K7 Primary Antibody for IHC, ELISA - ABIN1532056 : Mungall, Palmer, Sims, Edwards, Ashurst, Wilming, Jones, Horton, Hunt, Scott, Gilbert, Clamp, Bethel, Milne, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey, Banerjee, Barker et al.: The DNA sequence and analysis of human chromosome 6. ... in Nature 2003 (PubMed)
    Show all 2 references for ABIN1532056

  5. Human Polyclonal MAP3K7 Primary Antibody for ELISA, WB - ABIN185640 : Omori, Matsumoto, Sanjo, Sato, Akira, Smart, Ninomiya-Tsuji: TAK1 is a master regulator of epidermal homeostasis involving skin inflammation and apoptosis. in The Journal of biological chemistry 2006 (PubMed)
    Show all 2 references for ABIN185640

  6. Human Polyclonal MAP3K7 Primary Antibody for ELISA, WB - ABIN1532055 : Shibuya, Yamaguchi, Shirakabe, Tonegawa, Gotoh, Ueno, Irie, Nishida, Matsumoto: TAB1: an activator of the TAK1 MAPKKK in TGF-beta signal transduction. in Science (New York, N.Y.) 1996 (PubMed)
    Show all 2 references for ABIN1532055

  7. Human Polyclonal MAP3K7 Primary Antibody for EIA, WB - ABIN500865 : Yamaguchi, Shirakabe, Shibuya, Irie, Oishi, Ueno, Taniguchi, Nishida, Matsumoto: Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction. in Science (New York, N.Y.) 1996 (PubMed)

更多抗MAP3K7的相互作用对抗体

Human Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) interaction partners

  1. This study suggests that aberrant activity of TAK1 impairs autophagy and subsequently leads to alterations in the vitality of retinal pigment epithelial cells.

  2. TAK1 may be an important factor involved in the pathogenesis of thyroid cancer, and targeted down-regulation of TAK1 may improve the prognosis of patients with thyroid cancer.

  3. Loss of MAP3K7 are associated with esophageal squamous cell carcinoma.

  4. This paper highlights that targeting the BMP and TGFbeta (显示 TGFB1 抗体) type I and type II receptors causes a downregulation of XIAP (显示 XIAP 抗体), TAK1, and Id1 (显示 ID1 抗体) leading to cell death of lung cancer cells.

  5. Polyubiquitination of Transforming Growth Factor beta-activated Kinase 1 (TAK1) at Lysine 562 Residue Regulates TLR4 (显示 TLR4 抗体)-mediated JNK (显示 MAPK8 抗体) and p38 MAPK (显示 MAPK14 抗体) Activation

  6. The data emphasize the central role of TAK1 in controlling signaling cascades and functional responses in primary neutrophils, making it a promising target for therapeutic intervention in view of the role of neutrophils in chronic inflammatory conditions.

  7. MiR (显示 MLXIP 抗体)-377 is an important negative regulator of E2F (显示 E2F1 抗体) and MAP3K7/NF-kB signaling pathway in melanoma cells.

  8. the TAK1 signaling pathway may represent a suitable target to design new, antifibrotic therapies

  9. Findings indicate that SHIP2 (显示 INPPL1 抗体) is a regulator of lymphatic function in humans and that inherited mutations in the INPPL1 (显示 INPPL1 抗体) gene may act in concert with HGF (显示 HGF 抗体), and likely MAP3K7, mutations to exacerbate lymphatic phenotypes.

  10. Data indicate that inhibition of TGF-beta (显示 TGFB1 抗体)-activated protein kinase (显示 CDK7 抗体) 1 (TAK1) reduces chemokine (C-C motif) receptor 7 (CCR7 (显示 CCR7 抗体)) expression.

Mouse (Murine) Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) interaction partners

  1. TRIM8 (显示 TRIM8 抗体) could promote K63-linked polyubiquitination of transforming growth factor beta-activated kinase 1 (TAK1), leading to the activation of TAK1 (显示 NR2C2 抗体) and enhanced inflammatory responses.

  2. TAK1 (显示 NR2C2 抗体) signaling preserved the viability of lambda-chain-positive B cells by maintaining Bcl-2 (显示 BCL2 抗体) expression through IKK (显示 CHUK 抗体)-NF-kappaB (显示 NFKB1 抗体) signaling

  3. Data show that TGFbeta (显示 TGFB1 抗体)-activated kinase-1 (TAK1 (显示 NR2C2 抗体)) activated nuclear factor of activated T-cells (NFAT (显示 NFATC1 抗体))/NF-kappa B (NFkappaB (显示 NFKB1 抗体)), downregulated BCL2-adenovirus E1B interacting protein 3 (Bnip3 (显示 BNIP3 抗体)), and inhibited cardiac cell death.

  4. Crucial functions of inflammatory TAK1 (显示 NR2C2 抗体)-NEMO (显示 IKBKG 抗体) signaling in protecting the brain endothelium and maintaining normal brain function.

  5. Roles of TAK1 (显示 NR2C2 抗体) in vascular oxidative stress and its contribution to neointima formation after vascular injury.

  6. Inactivation of TAK1 (显示 NR2C2 抗体) in satellite cells inhibits muscle regeneration in adult mice.

  7. our current study highlighted the emerging role of TAK1 (显示 NR2C2 抗体) in configuring the gut (显示 GUSB 抗体)-specialized T cell subset, which regulates mucosal homeostasis under lymphopenic conditions.

  8. the ADAP (显示 APP 抗体) CARMA1 (显示 CARD11 抗体) binding site is required for IKK gamma (显示 IKBKG 抗体) ubiquitination; both TAK1 (显示 NR2C2 抗体) and CARMA1 (显示 CARD11 抗体) binding sites are required for IkappaB alpha (显示 NFKBIA 抗体) phosphorylation and degradation and NF-kappaB (显示 NFKB1 抗体) nuclear translocation

  9. Results provide evidence that TAK1 (显示 NR2C2 抗体) is required for the activation of NF-kappaB (显示 NFKB1 抗体) in thymocytes and suggest that TAK1 (显示 NR2C2 抗体) plays a central role in both innate and adaptive immunity.

  10. TAK1 (显示 NR2C2 抗体) is essential for connective tissue deposition in the dermis.

MAP3K7 抗原简介

Antigen Summary

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2\; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

Alternative names and synonyms associated with MAP3K7

  • mitogen activated protein kinase kinase kinase 7 (map3k7) 抗体
  • mitogen activated protein kinase kinase kinase 7 (Map3k7) 抗体
  • mitogen-activated protein kinase kinase kinase 7 (MAP3K7) 抗体
  • mitogen-activated protein kinase kinase kinase 7 (Map3k7) 抗体
  • B430101B05 抗体
  • C87327 抗体
  • MEKK7 抗体
  • si:ch211-225h9.1 抗体
  • TAK1 抗体
  • TGF1a 抗体
  • zgc:110612 抗体

Protein level used designations for MAP3K7

mitogen-activated protein kinase kinase kinase 7 , tak1 , TGF-beta-activated kinase TAK1 , TGF-beta activated kinase 1 , TGF-beta-activated kinase 1 , transforming growth factor-beta-activated kinase 1 , mitogen activated protein kinase kinase kinase 7 , transforming growth factor beta-activated kinase 1

GENE ID SPECIES
553788 Danio rerio
313121 Rattus norvegicus
6885 Homo sapiens
26409 Mus musculus
529146 Bos taurus
100171454 Pongo abelii
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