anti-MAP3K7 (MAP3K7) 抗体产品概述

Full name:
anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 抗体 (MAP3K7)
在www.antibodies-online.cn可供177 Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) 抗体的16不同的供货商。 再加上,我们可以发MAP3K7 试剂盒 (10)MAP3K7 蛋白 (7)和数多这个蛋白质的别的产品。 总共214 MAP3K7产品已列进来了。
别名:
B430101B05, C87327, MEKK7, si:ch211-225h9.1, TAK1, TGF1a, zgc:110612

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引用最多的anti-MAP3K7 抗体

  1. Human Polyclonal MAP3K7 Primary Antibody for EIA, IHC (p) - ABIN360354 : Takaesu, Surabhi, Park, Ninomiya-Tsuji, Matsumoto, Gaynor: TAK1 is critical for IkappaB kinase-mediated activation of the NF-kappaB pathway. in Journal of molecular biology 2003 (PubMed)
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  2. Human Polyclonal MAP3K7 Primary Antibody for EIA - ABIN358291 : Ono, Ohtomo, Ninomiya-Tsuji, Tsuchiya: A dominant negative TAK1 inhibits cellular fibrotic responses induced by TGF-beta. in Biochemical and biophysical research communications 2003 (PubMed)
    Show all 5 references for 358291

  3. Human Polyclonal MAP3K7 Primary Antibody for DB, EIA - ABIN358312 : Smit, Baas, Kuipers, Korswagen, van de Wetering, Clevers: Wnt activates the Tak1/Nemo-like kinase pathway. in The Journal of biological chemistry 2004 (PubMed)
    Show all 5 references for 358312

  4. Human Polyclonal MAP3K7 Primary Antibody for IHC, ELISA - ABIN1532056 : Mungall, Palmer, Sims, Edwards, Ashurst, Wilming, Jones, Horton, Hunt, Scott, Gilbert, Clamp, Bethel, Milne, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey, Banerjee, Barker et al.: The DNA sequence and analysis of human chromosome 6. ... in Nature 2003 (PubMed)
    Show all 2 references for 1532056

  5. Human Polyclonal MAP3K7 Primary Antibody for ELISA, WB - ABIN185640 : Omori, Matsumoto, Sanjo, Sato, Akira, Smart, Ninomiya-Tsuji: TAK1 is a master regulator of epidermal homeostasis involving skin inflammation and apoptosis. in The Journal of biological chemistry 2006 (PubMed)
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  6. Human Polyclonal MAP3K7 Primary Antibody for ELISA, WB - ABIN1532055 : Shibuya, Yamaguchi, Shirakabe, Tonegawa, Gotoh, Ueno, Irie, Nishida, Matsumoto: TAB1: an activator of the TAK1 MAPKKK in TGF-beta signal transduction. in Science (New York, N.Y.) 1996 (PubMed)
    Show all 2 references for 1532055

更多抗MAP3K7的相互作用对抗体

Human Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) interaction partners

  1. TAK1 regulates Nrf2 (显示 GABPA 抗体) through modulation of Keap-p62/SQSTM1 (显示 SQSTM1 抗体) interaction. This regulation is important for homeostatic antioxidant protection in the intestinal epithelium.

  2. Overexpression of TAK1 was strongly associated with positive lymph node metastasis in pancreatic ductal adenocarcinoma.

  3. dysregulation of the TAK1 complex produces a close phenocopy of Frontometaphyseal Dysplasia caused by FLNA (显示 FLNA 抗体) mutations; furthermore, the pathogenesis of some of the filaminopathies caused by FLNA (显示 FLNA 抗体) mutations might be mediated by misregulation of signaling coordinated through the TAK1 signaling complex

  4. although TAK1 is located at the crossroad of inflammation, immunity, and cancer, this study reports MAP3K7 mutations in a developmental disorder affecting mainly cartilage, bone, and heart

  5. This study suggests that aberrant activity of TAK1 impairs autophagy and subsequently leads to alterations in the vitality of retinal pigment epithelial cells.

  6. TAK1 may be an important factor involved in the pathogenesis of thyroid cancer, and targeted down-regulation of TAK1 may improve the prognosis of patients with thyroid cancer.

  7. Loss of MAP3K7 are associated with esophageal squamous cell carcinoma.

  8. This paper highlights that targeting the BMP and TGFbeta (显示 TGFB1 抗体) type I and type II receptors causes a downregulation of XIAP (显示 XIAP 抗体), TAK1, and Id1 (显示 ID1 抗体) leading to cell death of lung cancer cells.

  9. Polyubiquitination of Transforming Growth Factor beta-activated Kinase 1 (TAK1) at Lysine 562 Residue Regulates TLR4 (显示 TLR4 抗体)-mediated JNK (显示 MAPK8 抗体) and p38 MAPK (显示 MAPK14 抗体) Activation

  10. The data emphasize the central role of TAK1 in controlling signaling cascades and functional responses in primary neutrophils, making it a promising target for therapeutic intervention in view of the role of neutrophils in chronic inflammatory conditions.

Mouse (Murine) Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) interaction partners

  1. Transforming growth factor-beta activated kinase 1 (TAK1) regulation of sterol-regulatory element-binding proteins (SREBPs) critically contributes to the maintenance of liver homeostasis to prevent steatosis, which is a potentially important mechanism to prevent hepatocellular carcinoma (HCC (显示 FAM126A 抗体)) development.

  2. TAK1 (显示 NR2C2 抗体) regulates Nrf2 (显示 NFE2L2 抗体) through modulation of Keap-p62/SQSTM1 (显示 SQSTM1 抗体) interaction. This regulation is important for homeostatic antioxidant protection in the intestinal epithelium.

  3. Mekk1 (显示 MAP2K1 抗体) (encoded by Map3k1 (显示 MAP3K1 抗体)) signaling activates Mapks to regulate Cdkn1b (显示 CDKN1B 抗体) (encoding p27(Kip1 (显示 CDKN1B 抗体))) expression and p27(Kip1 (显示 CDKN1B 抗体))-dependent proliferative expansion in response to antigen.

  4. TRADD (显示 TRADD 抗体) knockout blunts pressure overload-induced cardiac hypertrophy through mediating TAK1 (显示 NR2C2 抗体)/p38 MAPK (显示 MAPK14 抗体) but not AKT (显示 AKT1 抗体) phosphorylation

  5. this study demonstrates a pivotal role of TAK1 (显示 NR2C2 抗体) in dendritic cells in controlling trichloroethylene-induced contact hypersensitivity response and suggests that targeting TAK1 (显示 NR2C2 抗体) function in DCs may be a viable approach to preventing and treating TCE-related occupational health hazards

  6. The E3 ligase TRIM8 (显示 TRIM8 抗体) is a potent regulator that exacerbates steatohepatitis and metabolic disorders dependent on its binding and ubiquitinating capacity on transforming growth factor-beta-activated kinase 1.

  7. Angiotensin-II up-regulates the Ampkalpha1 (显示 PRKAA1 抗体) isoform in renal tissue. Ampkalpha1 (显示 PRKAA1 抗体) participates in renal Tak1 (显示 NR2C2 抗体) activation and Tak1 (显示 NR2C2 抗体)-dependent signaling induced by angiotensin-II.

  8. TRIM8 (显示 TRIM8 抗体) could promote K63-linked polyubiquitination of transforming growth factor beta-activated kinase 1 (TAK1), leading to the activation of TAK1 (显示 NR2C2 抗体) and enhanced inflammatory responses.

  9. TAK1 (显示 NR2C2 抗体) signaling preserved the viability of lambda-chain-positive B cells by maintaining Bcl-2 (显示 BCL2 抗体) expression through IKK (显示 CHUK 抗体)-NF-kappaB (显示 NFKB1 抗体) signaling

  10. Data show that TGFbeta (显示 TGFB1 抗体)-activated kinase-1 (TAK1 (显示 NR2C2 抗体)) activated nuclear factor of activated T-cells (NFAT (显示 NFATC1 抗体))/NF-kappa B (NFkappaB (显示 NFKB1 抗体)), downregulated BCL2-adenovirus E1B interacting protein 3 (Bnip3 (显示 BNIP3 抗体)), and inhibited cardiac cell death.

MAP3K7 抗原简介

Antigen Summary

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2\; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

Alternative names and synonyms associated with MAP3K7

  • mitogen activated protein kinase kinase kinase 7 (map3k7) 抗体
  • mitogen activated protein kinase kinase kinase 7 (Map3k7) 抗体
  • mitogen-activated protein kinase kinase kinase 7 (MAP3K7) 抗体
  • mitogen-activated protein kinase kinase kinase 7 (Map3k7) 抗体
  • B430101B05 抗体
  • C87327 抗体
  • MEKK7 抗体
  • si:ch211-225h9.1 抗体
  • TAK1 抗体
  • TGF1a 抗体
  • zgc:110612 抗体

Protein level used designations for MAP3K7

mitogen-activated protein kinase kinase kinase 7 , tak1 , TGF-beta-activated kinase TAK1 , TGF-beta activated kinase 1 , TGF-beta-activated kinase 1 , transforming growth factor-beta-activated kinase 1 , mitogen activated protein kinase kinase kinase 7 , transforming growth factor beta-activated kinase 1

GENE ID SPECIES
553788 Danio rerio
313121 Rattus norvegicus
6885 Homo sapiens
26409 Mus musculus
529146 Bos taurus
100171454 Pongo abelii
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