anti-V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog A (Avian) (MAFA) 抗体产品概述

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anti-V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog A (Avian) 抗体 (MAFA)
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别名:
2F1-Ag, hMafA, L-MAF, MAFA, MAFA-L, mafl, RGD1562627, RIPE3b1, SMaf1

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引用最多的anti-V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog A (Avian) 抗体

  1. Human Polyclonal MAFA Primary Antibody for ChIP, GS - ABIN152904 : Wang, Torres-Gonzalez, Tripathy, Botolin, Christian, Jump: Elevated hepatic fatty acid elongase-5 activity affects multiple pathways controlling hepatic lipid and carbohydrate composition. in Journal of lipid research 2008 (PubMed)
    Show all 38 references for 152904

  2. Human Polyclonal MAFA Primary Antibody for EIA, WB - ABIN953282 : Garin, Martinez, de las Heras, Perez-Nanclares, Castano, Perez de Nanclares: Mutations in MAFA and IAPP are not a common cause of monogenic diabetes. in Diabetic medicine : a journal of the British Diabetic Association 2009 (PubMed)
    Show all 5 references for 953282

  3. Human Polyclonal MAFA Primary Antibody for EIA, WB - ABIN953280 : Lecoin, Rocques, El-Yakoubi, Ben Achour, Larcher, Pouponnot, Eychène: MafA transcription factor identifies the early ret-expressing sensory neurons. in Developmental neurobiology 2010 (PubMed)
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  4. Human Polyclonal MAFA Primary Antibody for EIA, WB - ABIN953281 : Martin, Flemming, Wang, Oeser, OBrien: Foxa2 and MafA regulate islet-specific glucose-6-phosphatase catalytic subunit-related protein gene expression. in Journal of molecular endocrinology 2008 (PubMed)
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  5. Dog (Canine) Polyclonal MAFA Primary Antibody for WB - ABIN2783128 : Matsuoka, Kaneto, Stein, Miyatsuka, Kawamori, Henderson, Kojima, Matsuhisa, Hori, Yamasaki: MafA regulates expression of genes important to islet beta-cell function. in Molecular endocrinology (Baltimore, Md.) 2007 (PubMed)

  6. Human Polyclonal MAFA Primary Antibody for WB - ABIN653392 : Kondo, El Khattabi, Nishimura, Laybutt, Geraldes, Shah, King, Bonner-Weir, Weir, Sharma: p38 MAPK is a major regulator of MafA protein stability under oxidative stress. in Molecular endocrinology (Baltimore, Md.) 2009 (PubMed)

更多抗V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog A (Avian)的相互作用对抗体

Mouse (Murine) V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog A (Avian) (MAFA) interaction partners

  1. Treg cell accumulation in intestinal tumours from APC (显示 APC 抗体)(min/+) mice was exclusively due to the increase in KLRG1 (显示 KLRG1 抗体)(+) GATA3 (显示 GATA3 抗体)(+) Treg cells.

  2. Although absence of KLRG1 (显示 KLRG1 抗体) is not enough to increase intestinal Treg cells in KLRG1 (显示 KLRG1 抗体) knockout mice, KLRG1 (显示 KLRG1 抗体) ligation reduces T-cell receptor signals and the competitive fitness of individual Treg cells in the intestine.

  3. Mafa was found to both potentiate the ability of Pdx1 (显示 PDX1 抗体) to induce beta-cell formation from Ngn3 (显示 NEUROG3 抗体)-positive endocrine precursors and enable Pdx1 (显示 PDX1 抗体) to produce beta-cells from alpha-cells.

  4. Ly6C, 4-1BB (显示 TNFRSF9 抗体), and KLRG1 (显示 KLRG1 抗体) have roles in the activation of lamina propria lymphocytes in the small intestine in a mouse model of Crohn's disease

  5. MAFA controls autonomic nervous system-mediated insulin secretion by activating the transcription of nicotinic (ChrnB2 and ChrnB4) receptor genes, which is impaired in type 2 diabetes.

  6. These findings demonstrate that regulation of monoamine levels by Mao (显示 MAO 抗体) activity in beta cells is pivotal for physiological insulin (显示 INS 抗体) secretion and that loss of MaoB (显示 MAOB 抗体) expression may contribute to the beta cell dysfunction in type 2 diabetes.

  7. is necessary for the maintenance of normal insulin (显示 INS 抗体) levels even in embryos.

  8. endogenous small-Maf (显示 MAF 抗体) factors negatively regulate beta-cell function by competing for MafA binding, and thus, the inhibition of small-Maf (显示 MAF 抗体) activity can improve beta-cell function

  9. Data, including data from studies using transgenic/knockout mice, confirm the expression of Mafa and Mafb (显示 MAFB 抗体) is specific to insulin (显示 INS 抗体)-secreting cells of the pancreas.

  10. These results suggest that MafA regulates the postnatal proliferation of beta-cells via prolactin (显示 PRL 抗体) signaling.

Human V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog A (Avian) (MAFA) interaction partners

  1. Pdx1 (显示 PDX1 抗体) and MafA (显示 KLRG1 抗体) play crucial roles in the pancreas and maintain mature beta-cell function. Our results showed that the expression of Pdx1 (显示 PDX1 抗体) and MafA (显示 KLRG1 抗体) were significantly upregulated after a sleeve gastrectomy for morbid obesity.

  2. MAFA controls autonomic nervous system-mediated insulin secretion by activating the transcription of nicotinic (ChrnB2 and ChrnB4) receptor genes, which is impaired in patients with type 2 diabetes.

  3. These findings demonstrate that regulation of monoamine levels by Mao (显示 MAO 抗体) activity in beta cells is pivotal for physiological insulin (显示 INS 抗体) secretion and that loss of MaoB (显示 MAOB 抗体) expression may contribute to the beta cell dysfunction in type 2 diabetes.

  4. MAFA (显示 KLRG1 抗体), MAFB (显示 MAFB 抗体), NKX6.1 (显示 NKX6-1 抗体), and PDX1 (显示 PDX1 抗体) activity provides a gauge of islet beta cell function, with loss of MAFA (显示 KLRG1 抗体) (and/or MAFB (显示 MAFB 抗体)) representing an early indicator of beta cell inactivity

  5. Loss of MAFA (显示 KLRG1 抗体) expression is associated with insulinoma (显示 RPS15 抗体).

  6. MAFA (显示 KLRG1 抗体) nuclear expression in pancreatic alpha and beta cells, and the percentage of alpha cells expressing PAX4 (显示 PAX4 抗体) are altered in patients with type 2 diabetes.

  7. under oxidative and nonoxidative conditions p38 MAPK (显示 MAPK14 抗体) directly binds to MafA (显示 KLRG1 抗体) and triggers MafA (显示 KLRG1 抗体) degradation via ubiquitin proteasomal pathway.

  8. Beta cell nuclear MafA (显示 KLRG1 抗体) is markedly decreased in humans with type 2 diabetes, which may contribute to impaired beta cell dysfunction.

  9. Combined transfection of the three transcriptional factors, PDX-1 (显示 PDX1 抗体), NeuroD1 (显示 NEUROD1 抗体), and MafA (显示 KLRG1 抗体), causes differentiation of bone marrow mesenchymal stem cells into insulin (显示 INS 抗体)-producing cells

  10. Data suggest that MafA (显示 KLRG1 抗体) plays a novel role in the reprogramming of stem cells into pancreatic beta-progenitors, promotes the islet-like characteristics of PDMSCs, as well as functionally regulation of blood glucose levels in transplanted grafts.

V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog A (Avian) (MAFA) 抗原简介

Antigen Summary

MAFA is a transcription factor that binds RIPE3b, a conserved enhancer element that regulates pancreatic beta cell-specific expression of the insulin gene (INS\; MIM 176730) (Olbrot et al., 2002

Alternative names and synonyms associated with V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog A (Avian) (MAFA)

  • killer cell lectin-like receptor subfamily G, member 1 (Klrg1) 抗体
  • v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (mafa) 抗体
  • v-maf avian musculoaponeurotic fibrosarcoma oncogene A (Mafa) 抗体
  • v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A (MAFA) 抗体
  • v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian) (Mafa) 抗体
  • v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (MAFA) 抗体
  • v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian) (mafa) 抗体
  • 2F1-Ag 抗体
  • hMafA 抗体
  • L-MAF 抗体
  • MAFA 抗体
  • MAFA-L 抗体
  • mafl 抗体
  • RGD1562627 抗体
  • RIPE3b1 抗体
  • SMaf1 抗体

Protein level used designations for MAFA

killer cell lectin-like receptor subfamily G member 1 , mast cell function-associated antigen 2F1 , mast cell function-associated antigen , v-maf musculoaponeurotic fibrosarcoma oncogene homolog A , Transcription factor MafA , leucine zipper transcription factor , v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A , pancreatic beta-cell-specific transcriptional activator , transcription factor MafA , transcription factor RIPE3b1 , Mafa homolog , V-maf musculoaponeurotic fibrosarcoma oncogene homolog A , bZIP transcription factor L-Maf , lens-specific Maf , somite Maf1 , v-maf musculoaponeurotic fibrosarcoma oncogene family, protein L

GENE ID SPECIES
50928 Mus musculus
58975 Rattus norvegicus
613050 Xenopus (Silurana) tropicalis
366949 Rattus norvegicus
389692 Homo sapiens
378435 Mus musculus
395881 Gallus gallus
100000492 Danio rerio
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