anti-DACH1 (DACH1) 抗体产品概述

Full name:
anti-Dachshund Homolog 1 (Drosophila) 抗体 (DACH1)
在www.antibodies-online.cn可供78 Dachshund Homolog 1 (Drosophila) (DACH1) 抗体的18不同的供货商。 再加上,我们可以发DACH1 蛋白 (3)DACH1 试剂盒 (2)和数多这个蛋白质的别的产品。 总共89 DACH1产品已列进来了。
别名:
AI182278, Dac, DACH, E130112M23Rik, zgc:158869
列出全部抗体 基因 基因ID UniProt
DACH1 13134 Q9QYB2
DACH1 1602 Q9UI36
DACH1    

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引用最多的anti-DACH1 抗体

  1. Human Polyclonal DACH1 Primary Antibody for ICC, IF - ABIN4304211 : Powe, Dhondalay, Lemetre, Allen, Habashy, Ellis, Rees, Ball: DACH1: its role as a classifier of long term good prognosis in luminal breast cancer. in PLoS ONE 2014 (PubMed)
    Show all 4 references for 4304211

  2. Human Polyclonal DACH1 Primary Antibody for WB - ABIN2778443 : Wu, Katiyar, Li, Liu, Ju, Popov, Jiao, Lisanti, Casola, Pestell: Dachshund inhibits oncogene-induced breast cancer cellular migration and invasion through suppression of interleukin-8. in Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)

  3. Human Polyclonal DACH1 Primary Antibody for ELISA, WB - ABIN314239 : Wu, Yang, Wang, Davoli, DAmico, Li, Cveklova, Kozmik, Lisanti, Russell, Cvekl, Pestell: DACH1 inhibits transforming growth factor-beta signaling through binding Smad4. in The Journal of biological chemistry 2003 (PubMed)

更多抗DACH1的相互作用对抗体

Mouse (Murine) Dachshund Homolog 1 (Drosophila) (DACH1) interaction partners

  1. HDAC4 (显示 HDAC5 抗体)-mediated SUMOylation of the corepressor DACH1 is decreased, which protects DACH1 from proteasomal degradation

  2. The results of this study suggested the involvement of the mouse Dach1 gene in adult neurogenesis; cells expressing this gene exhibit the properties of adult NSCs or neuroblasts and respond to MCAo by enhanced neurogenesis.

  3. find that in cells growing in IGF-1 (显示 IGF1 抗体) (and unresponsive to EGF (显示 EGF 抗体)), DACH1 is devoid of tumor suppressor activity

  4. The mouse dachshund gene is related to the Ski (显示 SKI 抗体) proto-oncogene (显示 RAB1A 抗体) and is expressed in eye and limb.

  5. In the mouse, Dach1 expression in the developing ear also overlaps with the expression of Eya1 (显示 EYA1 抗体) (an eya homologue)

  6. Dach1 is a target gene of FGF signaling during limb skeletal development, and Dach1 may function as an intermediary in the FGF signaling pathway regulating cell proliferation or differentiation

  7. Dach1 is critical for postnatal survival of mice

  8. The phosphatase function of Eya switches the function of Six1 (显示 SIX1 抗体)-Dach from repression to activation, causing transcriptional activation through recruitment of co-activators

  9. The Pax (显示 PXN 抗体)-Eya-Six-Dach network is at best only partly conserved during lens and nasal placode development.

  10. DACH1 repressed cyclin D1 (显示 CCND1 抗体) through a novel mechanism via a c-Jun (显示 JUN 抗体) DNA-binding partner, requiring the DACH1 alpha-helical DS domain which recruits corepressors to the local chromatin.

Human Dachshund Homolog 1 (Drosophila) (DACH1) interaction partners

  1. Knockdown of DACH1 expression can remarkably enhance the cell apoptosis, restrain the proliferation, migration and invasion of Capan-1 cells.

  2. DACH1 expression regulates the pancreatic cancer cell apoptosis.

  3. Low DACH1 expression is associated with invasion of lung adenocarcinoma.

  4. This study concludes that MiR (显示 MLXIP 抗体)-217 is the upstream regulator of PGC-1alpha (显示 PPARGC1A 抗体) in breast cancer regulation in vitro, possibly independent of DACH1 signaling pathway.

  5. Kaplan-Mier analysis of human NSCLC samples demonstrated that high DACH1 mRNA levels predicted favorable prognosis for relapse-free and overall survival. In agreement, high CXCL5 (显示 CXCL5 抗体) expression predicted a worse prognosis for survival.

  6. DACH1 expression was reduced in hepatocellular carcinoma even at early stage and associated with tumor progression. Overexpression inhibited HCC (显示 FAM126A 抗体) cell growth and migration by inactivating the Wnt (显示 WNT2 抗体) pathway via GSK3beta (显示 GSK3b 抗体) phosphorylation to suppress beta-catenin (显示 CTNNB1 抗体).

  7. In breast cancer, some GATA3 (显示 GATA3 抗体) effects shift from tumor suppressing to tumor promoting during tumorigenesis, with deregulation of three genes, BCL2 (显示 BCL2 抗体), DACH1, THSD4, representing major GATA3 (显示 GATA3 抗体)-controlled processes in cancer progression.

  8. Results indicated that DACH1 was a novel molecular marker of RCC (显示 XRCC1 抗体) and it attributed to the malignant behavior of renal cancer cells.

  9. Data indicate that dachshund family transcription factor 1 (显示 HNF1A 抗体) (DACH1) suppresses gastric cancer cell proliferation, invasion and metastasis by inhibiting transforming growth factor beta (TGF-beta) signalling pathways both in vitro and in vivo.

  10. results suggest that DACH1 loss of function results in increased cell growth, motility and invasiveness through TGF-beta (显示 TGFB1 抗体)-mediated EMT (显示 ITK 抗体), and DACH1 loss of function has important therapeutic implications for targeted therapies of CRC (显示 CALR 抗体)

DACH1 抗原简介

Antigen Summary

This gene encodes a chromatin-associated protein that associates with other DNA-binding transcription factors to regulate gene expression and cell fate determination during development. The protein contains a Ski domain that is highly conserved from Drosophila to human. Expression of this gene is lost in some forms of metastatic cancer, and is correlated with poor prognosis. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with DACH1

  • dachshund homolog 1 (Drosophila) (DACH1) 抗体
  • dachshund homolog 1 (dach1) 抗体
  • dachshund d (dachd) 抗体
  • dachshund homolog 1 (Drosophila) (dach1) 抗体
  • dachshund 1 (Drosophila) (Dach1) 抗体
  • AI182278 抗体
  • Dac 抗体
  • DACH 抗体
  • E130112M23Rik 抗体
  • zgc:158869 抗体

Protein level used designations for DACH1

dachshund homolog 1 (Drosophila) , dachshund homolog 1 , dachshund 1 , dachshund protein , dachshund homolog 1-like

GENE ID SPECIES
467281 Pan troglodytes
779068 Xenopus laevis
779442 Xenopus (Silurana) tropicalis
791191 Danio rerio
100303544 Saccoglossus kowalevskii
693532 Macaca mulatta
100010972 Monodelphis domestica
100224395 Taeniopygia guttata
100466304 Ailuropoda melanoleuca
100550020 Meleagris gallopavo
100553703 Anolis carolinensis
100595110 Nomascus leucogenys
13134 Mus musculus
1602 Homo sapiens
485489 Canis lupus familiaris
100156238 Sus scrofa
373935 Gallus gallus
100065685 Equus caballus
537184 Bos taurus
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