anti-AP2S1 (AP2S1) 抗体产品概述

Full name:
anti-Adaptor-Related Protein Complex 2, sigma 1 Subunit 抗体 (AP2S1)
在www.antibodies-online.cn可供37 Adaptor-Related Protein Complex 2, sigma 1 Subunit (AP2S1) 抗体的8不同的供货商。 再加上,我们可以发AP2S1 蛋白 (13)AP2S1 试剂盒 (2)和数多这个蛋白质的别的产品。 总共55 AP2S1产品已列进来了。
AI043088, AP2S1, Ap17, AP17-DELTA, CLAPS2, DDBDRAFT_0188542, DDBDRAFT_0234236, DDB_0188542, DDB_0234236, HHC3, MGC85224

最受欢迎的抗anti-AP2S1 (AP2S1) 抗体


抗Human AP2S1 抗体:

抗Mouse (Murine) AP2S1 抗体:

抗Rat (Rattus) AP2S1 抗体:

所有可销售的anti-AP2S1 抗体


引用最多的anti-AP2S1 抗体

  1. Human Monoclonal AP2S1 Primary Antibody for WB - ABIN394535 : Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: Large-scale mapping of human protein-protein interactions by mass spectrometry. ... in Molecular systems biology 2007 (PubMed)
    Show all 5 references for 394535


Human Adaptor-Related Protein Complex 2, sigma 1 Subunit (AP2S1) interaction partners

  1. CaSR (显示 CASR 抗体) and AP2S1 sequencing is worthwhile in patients with familial hyperparathyroidism and phenotype suggesting familial hypocalciuric hypercalcemia as it can diagnose up to 50% of cases.

  2. In 33 CASR (显示 CASR 抗体)-negative patients with suspected FHH (显示 CASR 抗体), Data found two (~6%) with a mutation in AP2S1 (p.Arg15Leu and p.Arg15His). Family screening confirmed the genotype-phenotype correlations. Data did not identify any pathogenic mutations in GNA11 (显示 GNA11 抗体).

  3. our studies demonstrate AP2sigma2 mutations to result in a more severe FHH (显示 CASR 抗体) phenotype with genotype-phenotype correlations, and a dominant-negative mechanism of action with mutational bias at the Arg15 residue.

  4. The results affirm that a significant number of patients suspected of having Familial hypocalciuric hypercalcemia but proven negative for CASR (显示 CASR 抗体) mutation have AP2S1 p.R15 mutations.

  5. The absence of AP2S1 abnormalities in hypocalcemic patients, suggests that autosomal dominant hypocalcemia 3 (ADH3) may not occur or otherwise represents a rare hypocalcemic disorder.

  6. None of the 60 patients presented with nucleotidic changes or copy number variation in the AP2S1 gene, thereby excluding AP2S1 defects as a frequent cause of isolated hypoparathyroidism.

  7. Mutations in AP2S1 cause familial hypocalciuric hypercalcemia type 3.

AP2S1 抗原简介

Antigen Summary

One of two major clathrin-associated adaptor complexes, AP-2, is a heterotetramer which is associated with the plasma membrane. This complex is composed of two large chains, a medium chain, and a small chain. This gene encodes the small chain of this complex. Alternative splicing has been observed in this gene and results in two known transcripts.

Alternative names and synonyms associated with AP2S1

  • adaptor-related protein complex 2, sigma 1 subunit (AP2S1) 抗体
  • adaptor-related protein complex 2, sigma 1 subunit (ap2s1) 抗体
  • adaptor-related protein complex 2, sigma 1 subunit (Ap2s1) 抗体
  • AI043088 抗体
  • AP2S1 抗体
  • Ap17 抗体
  • AP17-DELTA 抗体
  • CLAPS2 抗体
  • DDBDRAFT_0188542 抗体
  • DDBDRAFT_0234236 抗体
  • DDB_0188542 抗体
  • DDB_0234236 抗体
  • HHC3 抗体
  • MGC85224 抗体

Protein level used designations for AP2S1

adaptor-related protein complex 2, sigma 1 subunit , AP-2 complex subunit sigma , AP-2 complex subunit sigma isoform AP17 , sigma adaptin , HA2 17 kDa subunit , adaptor protein complex AP-2 subunit sigma , clathrin assembly protein 2 small chain , clathrin coat assembly protein AP17 , clathrin coat-associated protein AP17 , clathrin-associated/assembly/adaptor protein, small 2 (17kD) , plasma membrane adaptor AP-2 17 kDa protein , sigma2-adaptin , adapter-related protein complex 2 sigma subunit , sigma-adaptin 3b , clathrin-associated protein 17 , AP-2 complex subunit sigma-1

431511 Gallus gallus
456156 Pan troglodytes
549079 Xenopus (Silurana) tropicalis
716911 Macaca mulatta
8627289 Dictyostelium discoideum AX4
447078 Xenopus laevis
476427 Canis lupus familiaris
1175 Homo sapiens
232910 Mus musculus
65046 Rattus norvegicus
536553 Bos taurus
100172940 Pongo abelii
anti-AP2S1 (AP2S1) 抗体 精选生产商