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anti-Complement Factor H (CFH) 抗体产品概述

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anti-Complement Factor H 抗体 (CFH)
在www.antibodies-online.cn可供264 Complement Factor H (CFH) 抗体的27不同的供货商。 再加上,我们可以发Complement Factor H 试剂盒 (53)Complement Factor H 蛋白 (20)和数多这个蛋白质的别的产品。 总共346 Complement Factor H产品已列进来了。
别名:
AHUS1, AMBP1, ARMD4, ARMS1, CFH, CFHL3, fH, FHL1, HF, HF1, HF2, HUS, im:7147412, Mud-1, NOM, Sas-1, Sas1, si:ch211-207o17.2

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引用最多的anti-Complement Factor H 抗体

  1. Human Monoclonal Complement Factor H Primary Antibody for FACS - ABIN2660858 : Ripoche, Day, Harris, Sim: The complete amino acid sequence of human complement factor H. in The Biochemical journal 1988 (PubMed)
    Show all 6 references for ABIN2660858

  2. Human Polyclonal Complement Factor H Primary Antibody for EIA, IF - ABIN951646 : Dieterich, Hammerschmidt, Richter, Skerka, Wallich, Matuschka, Zipfel, Kraiczy: Inadequate binding of immune regulator factor H is associated with sensitivity of Borrelia lusitaniae to human complement. in Infection and immunity 2010 (PubMed)
    Show all 3 references for ABIN951646

  3. Human Monoclonal Complement Factor H Primary Antibody for EIA, FACS - ABIN181114 : Alexander, Quigg: The simple design of complement factor H: Looks can be deceiving. in Molecular immunology 2006 (PubMed)
    Show all 2 references for ABIN181114

  4. Human Polyclonal Complement Factor H Primary Antibody for IF, IHC (p) - ABIN654896 : Scambi, La Verde, De Franceschi, Barausse, Poli, Benedetti, Sorio, Deriu, Roncada, Bortolami, Turrini, Caramaschi, Stranieri, Bambara, Biasi: Comparative proteomic analysis of serum from patients with systemic sclerosis and sclerodermatous GVHD. Evidence of defective function of factor H. in PLoS ONE 2010 (PubMed)
    Show all 2 references for ABIN654896

  5. Horse (Equine) Polyclonal Complement Factor H Primary Antibody for EIA, ID - ABIN113017 : Chung, Liszewski, Nybakken, Davis, Townsend, Fremont, Atkinson, Diamond: West Nile virus nonstructural protein NS1 inhibits complement activation by binding the regulatory protein factor H. in Proceedings of the National Academy of Sciences of the United States of America 2006 (PubMed)

  6. Human Polyclonal Complement Factor H Primary Antibody for ELISA, WB - ABIN250548 : Klein, Zeiss, Chew, Tsai, Sackler, Haynes, Henning, SanGiovanni, Mane, Mayne, Bracken, Ferris, Ott, Barnstable, Hoh: Complement factor H polymorphism in age-related macular degeneration. in Science (New York, N.Y.) 2005 (PubMed)

更多抗Complement Factor H的相互作用对抗体

Chimpanzee Complement Factor H (CFH) interaction partners

  1. interaction between sialylated Neisseria gonorrhoeae and factor H [factor H]

Zebrafish Complement Factor H (CFH) interaction partners

  1. Results report the molecular cloning and identification of complement factor H and complement factor H-like 1-4 (CFHL1 (显示 CFHR1 抗体)-4) in Danio rerio.

Mouse (Murine) Complement Factor H (CFH) interaction partners

  1. absence of plasma CfH conferred susceptibility to glomerulonephritis

  2. This new understanding of the complicated interactions of CFH in AMD (显示 AMD1 抗体)-like pathology provides an improved foundation for the development of targeted therapies for AMD (显示 AMD1 抗体)

  3. data suggest that altered interactions of Cfh with MDA-modified proteins may be relevant in explaining the effects of the Cfh variant.

  4. Cfh and Cfhr2 (显示 CFHR2 抗体) genes are expressed in the mouse outer retina. Only Cfh mRNA was detected in the retinal pigment epithelium, but no protein.

  5. A spectrum of complement dysregulation was modeled on the APOE4 age related macular degeneration mouse model by crossing these mice to complement factor H knockout (cfh-/-) mice to test the impact of excess complement activation.

  6. Data indicate that co-deficiency of factor H (FH) and MASP-1/MASP-3 (显示 MASP1 抗体) did not ameliorate either the plasma Complement C3 (显示 C3 抗体) (C3) activation or glomerular C3 accumulation in FH-deficient mice.

  7. A2E accumulation altered retinal microglial complement regulation by decreasing complement factor H (and increasing complement factor B (显示 CFB 抗体) expression), favoring increased complement activation and lipofuscin deposition in the outer retina.

  8. The exaggerated humoral immune response in CFH(-/-) mice was normalized in CFH(-/-)C5aR (显示 C5AR1 抗体)(-/-) double knockout mice, highlighting the C5aR (显示 C5AR1 抗体) dependence.

  9. Properdin (显示 CFB 抗体) deficiency exacerbated renal injury in mice lacking complement factor H.

  10. IL-27 (显示 IL27 抗体) regulates complement activation through up-regulation of complement factor H in the retina.

Human Complement Factor H (CFH) interaction partners

  1. CFH, ARMS2 (显示 ARMS2 抗体), and C3 were associated with specific features of neovascularization at the time patients were enrolled in Comparison of Age-Related Macular Degeneration Treatments Trials .

  2. Even pathogens can exploit factor H. In fact, the ability to bind factor H discriminates most pathogenic microbes from nonpathogenic ones.

  3. Moreover, the binding of Escherichia coli OmpW to human factor H, a major inhibitor of alternative complement pathway, was found, indicating that OmpW recruitment of factor H is a mechanism for bacterial evasion of complement attack.

  4. Subfoveal choroidal thickness and choroidal vascular hyperpermeability in eyes with treatment-naive polypoidal choroidal vasculopathy were associated with ARMS2 (显示 ARMS2 抗体) A69S (rs10490924) and CFH (rs1329428).

  5. The principal CFH genotypes that induce liver-kidney yin-deficiency age-related macular degeneration (AMD (显示 AMD1 抗体)) are the mutant homozygote CC and heterozygote TC forms. Moreover, C allele carriers are at higher risk of developing this disease.

  6. The results of western blotting revealed that the protein expression levels of FH and FHL1 (显示 FHL1 抗体) were not regulated by IL6 (显示 IL6 抗体) and IL8 (显示 IL8 抗体) in a dosedependent manner. Immunofluorescence analysis confirmed that the A2780 ovarian cancer cell line expressed both membrane bound and intracellular forms of FH and FHL1 (显示 FHL1 抗体).

  7. CFH Y402H SNP might be protective for AMD in the Turkish population. VEGF rs2146323 and rs699947 SNPs have no relationship to exudative AMD formation, and none of these seem to have any effect on anti-VEGF response.

  8. AG genotype of CCL2 (显示 CCL2 抗体)-2518 in combination with TT genotype of CFH Y402H showed significant protective effect against age-related macular degeneration.

  9. The polymorphism rs1061170/Y402H might be a genetic predictor of treatment response to anti-VEGF (显示 VEGFA 抗体) therapy in AMD (显示 AMD1 抗体) patients.

  10. In this article, the authors investigated the use of complement inhibitor factor H (FH) on complement activation and showed good efficacy. The results would therefore suggest the potential application of complement inhibitor in the future

Pig (Porcine) Complement Factor H (CFH) interaction partners

Complement Factor H (CFH) 抗原简介

Antigen Summary

This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Alternative names and synonyms associated with Complement Factor H (CFH)

  • complement factor H (CFH) 抗体
  • complement factor H (cfh) 抗体
  • complement component factor h (Cfh) 抗体
  • complement factor H (Cfh) 抗体
  • AHUS1 抗体
  • AMBP1 抗体
  • ARMD4 抗体
  • ARMS1 抗体
  • CFH 抗体
  • CFHL3 抗体
  • fH 抗体
  • FHL1 抗体
  • HF 抗体
  • HF1 抗体
  • HF2 抗体
  • HUS 抗体
  • im:7147412 抗体
  • Mud-1 抗体
  • NOM 抗体
  • Sas-1 抗体
  • Sas1 抗体
  • si:ch211-207o17.2 抗体

Protein level used designations for anti-Complement Factor H (CFH) 抗体

complement factor H , complement factor H related protein 3A4/5G4 , protein beta-1-H , H factor 1 (complement) , H factor 2 (complement) , adrenomedullin binding protein , age-related maculopathy susceptibility 1 , beta-1-H-globulin , beta-1H , factor H , factor H-like 1 , complement component factor H , complement inhibitory factor H , platelet complement factor H , complement regulator factor H

GENE ID SPECIES
457601 Pan troglodytes
553060 Danio rerio
553297 Danio rerio
100399888 Callithrix jacchus
100451270 Pongo abelii
100465619 Ailuropoda melanoleuca
100600041 Nomascus leucogenys
12628 Mus musculus
3075 Homo sapiens
100051358 Equus caballus
155012 Rattus norvegicus
478952 Canis lupus familiaris
100733902 Cavia porcellus
100340175 Oryctolagus cuniculus
397525 Sus scrofa
280816 Bos taurus
429057 Gallus gallus
100174982 Ovis aries
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