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anti-Complement Factor H (CFH) 抗体产品概述

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anti-Complement Factor H 抗体 (CFH)
在www.antibodies-online.cn可供257 Complement Factor H (CFH) 抗体的26不同的供货商。 再加上,我们可以发Complement Factor H 试剂盒 (56)Complement Factor H 蛋白 (19)和数多这个蛋白质的别的产品。 总共341 Complement Factor H产品已列进来了。
别名:
AHUS1, AMBP1, ARMD4, ARMS1, CFH, CFHL3, fH, FHL1, HF, HF1, HF2, HUS, im:7147412, Mud-1, NOM, Sas-1, Sas1, si:ch211-207o17.2

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引用最多的anti-Complement Factor H 抗体

  1. Human Monoclonal Complement Factor H Primary Antibody for FACS - ABIN2660858 : Ripoche, Day, Harris, Sim: The complete amino acid sequence of human complement factor H. in The Biochemical journal 1988 (PubMed)
    Show all 6 references for ABIN2660858

  2. Human Polyclonal Complement Factor H Primary Antibody for EIA, IF - ABIN951646 : Dieterich, Hammerschmidt, Richter, Skerka, Wallich, Matuschka, Zipfel, Kraiczy: Inadequate binding of immune regulator factor H is associated with sensitivity of Borrelia lusitaniae to human complement. in Infection and immunity 2010 (PubMed)
    Show all 3 references for ABIN951646

  3. Human Monoclonal Complement Factor H Primary Antibody for EIA, FACS - ABIN181114 : Alexander, Quigg: The simple design of complement factor H: Looks can be deceiving. in Molecular immunology 2006 (PubMed)
    Show all 2 references for ABIN181114

  4. Human Polyclonal Complement Factor H Primary Antibody for IF, IHC (p) - ABIN654896 : Scambi, La Verde, De Franceschi, Barausse, Poli, Benedetti, Sorio, Deriu, Roncada, Bortolami, Turrini, Caramaschi, Stranieri, Bambara, Biasi: Comparative proteomic analysis of serum from patients with systemic sclerosis and sclerodermatous GVHD. Evidence of defective function of factor H. in PLoS ONE 2010 (PubMed)
    Show all 2 references for ABIN654896

  5. Horse (Equine) Polyclonal Complement Factor H Primary Antibody for EIA, ID - ABIN113017 : Chung, Liszewski, Nybakken, Davis, Townsend, Fremont, Atkinson, Diamond: West Nile virus nonstructural protein NS1 inhibits complement activation by binding the regulatory protein factor H. in Proceedings of the National Academy of Sciences of the United States of America 2006 (PubMed)

  6. Human Polyclonal Complement Factor H Primary Antibody for ELISA, WB - ABIN250548 : Klein, Zeiss, Chew, Tsai, Sackler, Haynes, Henning, SanGiovanni, Mane, Mayne, Bracken, Ferris, Ott, Barnstable, Hoh: Complement factor H polymorphism in age-related macular degeneration. in Science (New York, N.Y.) 2005 (PubMed)

更多抗Complement Factor H的相互作用对抗体

Chimpanzee Complement Factor H (CFH) interaction partners

  1. interaction between sialylated Neisseria gonorrhoeae and factor H [factor H]

Zebrafish Complement Factor H (CFH) interaction partners

  1. Results report the molecular cloning and identification of complement factor H and complement factor H-like 1-4 (CFHL1 (显示 CFHR1 抗体)-4) in Danio rerio.

Mouse (Murine) Complement Factor H (CFH) interaction partners

  1. environmental factors can drive retinal disease in these mice when linked to complement deficits impairing immune function. Both groups of mice had similar levels of retinal amyloid beta accumulation. Consequently there is no direct link between this and inflammation in Cfh(-/-) mice.

  2. absence of plasma CfH conferred susceptibility to glomerulonephritis

  3. This new understanding of the complicated interactions of CFH in AMD (显示 AMD1 抗体)-like pathology provides an improved foundation for the development of targeted therapies for AMD (显示 AMD1 抗体)

  4. data suggest that altered interactions of Cfh with MDA-modified proteins may be relevant in explaining the effects of the Cfh variant.

  5. Cfh and Cfhr2 (显示 CFHR2 抗体) genes are expressed in the mouse outer retina. Only Cfh mRNA was detected in the retinal pigment epithelium, but no protein.

  6. A spectrum of complement dysregulation was modeled on the APOE4 age related macular degeneration mouse model by crossing these mice to complement factor H knockout (cfh-/-) mice to test the impact of excess complement activation.

  7. Data indicate that co-deficiency of factor H (FH) and MASP-1/MASP-3 (显示 MASP1 抗体) did not ameliorate either the plasma Complement C3 (显示 C3 抗体) (C3) activation or glomerular C3 accumulation in FH-deficient mice.

  8. A2E accumulation altered retinal microglial complement regulation by decreasing complement factor H (and increasing complement factor B (显示 CFB 抗体) expression), favoring increased complement activation and lipofuscin deposition in the outer retina.

  9. The exaggerated humoral immune response in CFH(-/-) mice was normalized in CFH(-/-)C5aR (显示 C5AR1 抗体)(-/-) double knockout mice, highlighting the C5aR (显示 C5AR1 抗体) dependence.

  10. Properdin (显示 CFB 抗体) deficiency exacerbated renal injury in mice lacking complement factor H.

Human Complement Factor H (CFH) interaction partners

  1. Our results show that age-related macular degeneration donors carrying the high risk allele for CFH (C) had significantly more mtDNA damage compared with donors having the wild-type genetic profile.

  2. Data suggest that Staphylococcus aureus surface protein SdrE (serine-aspartate repeat protein E (显示 CRISP1 抗体)) functions as a 'clamp (显示 PDZK1 抗体)' to capture C-terminal tail of human CFH (complement factor H) at a specific ligand-binding site/groove via unique close-dock-lock-latch mechanism and thereby sequesters CFH on surface of S. aureus for complement evasion (immune evasion).

  3. The haplotypic coinheritance of potentially functional variants (including missense variants, novel splice sites, and the CFHR3 (显示 CFHR3 抗体)-CFHR1 (显示 CFHR1 抗体) deletion) was described for the four common haplotypes. Expression of the short and long CFH transcripts differed markedly between the retina and liver.

  4. Data suggest that complement factor H (CFH) attaches to surface of host cells to inhibit complement activation and amplification, preventing destruction of the host cells; SdrE (serine-aspartate repeat protein) of Staphylococcus aureus binds to CFH allowing S. aureus to mimic a host cell and reducing bacterial killing by granulocytes. [Commentary]

  5. Interaction effects between supplement groups and individual complement factor H (CFH) Y402H and age-related maculopathy susceptibility 2 (ARMS2 (显示 ARMS2 抗体)) genotypes, and composite genetic risk groups combining the number of risk alleles for both loci, were evaluated for their association with progression

  6. EMD (显示 EMD 抗体) were not AMD (显示 AMD1 抗体)-independently associated with CFH or ARMS2 (显示 ARMS2 抗体) genotypes. Our results indicate that patients without AMD (显示 AMD1 抗体) but with EMD (显示 EMD 抗体) can serve as controls in studies evaluating AMD (显示 AMD1 抗体) risk factors.

  7. Despite limited power of this pilot study, our results suggest an association of HF with polymorphisms in ARMS2 (显示 ARMS2 抗体)/HTRA1 (显示 HTRA1 抗体), CFH, APOE4/TOMM40 (显示 TOMM40 抗体), and VEGFA (显示 VEGFA 抗体) genes which could be triggered by modification of the extracellular matrix, altered complement system or lipid metabolism.

  8. data suggest that R1210C is a unique C-terminal complement factor H mutation that behaves as a partial complement factor H deficiency, predisposing individuals to diverse pathologies with distinct underlying pathogenic mechanisms; the final disease outcome is then determined by R1210C-independent genetic risk factors

  9. AMD (显示 AMD1 抗体) progression rate is influenced by CFH, and suggest that variants within CFH may have different effects on risk versus progression. However, since CFH:rs10737680 was not significant after Bonferroni correction and explained only a relatively small portion of variation in progression rate beyond that explained by age

  10. We describe a novel CFH/CFHR3 (显示 CFHR3 抗体) hybrid gene secondary to a de novo 6.3-kb deletion that arose through microhomology-mediated end joining rather than nonallelic homologous recombination. We confirmed a transcript from this hybrid gene and showed a secreted protein product that lacks the recognition domain of factor H and exhibits impaired cell surface complement regulation

Pig (Porcine) Complement Factor H (CFH) interaction partners

Complement Factor H (CFH) 抗原简介

Antigen Summary

This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Alternative names and synonyms associated with Complement Factor H (CFH)

  • complement factor H (CFH) 抗体
  • complement factor H (cfh) 抗体
  • complement component factor h (Cfh) 抗体
  • complement factor H (Cfh) 抗体
  • AHUS1 抗体
  • AMBP1 抗体
  • ARMD4 抗体
  • ARMS1 抗体
  • CFH 抗体
  • CFHL3 抗体
  • fH 抗体
  • FHL1 抗体
  • HF 抗体
  • HF1 抗体
  • HF2 抗体
  • HUS 抗体
  • im:7147412 抗体
  • Mud-1 抗体
  • NOM 抗体
  • Sas-1 抗体
  • Sas1 抗体
  • si:ch211-207o17.2 抗体

Protein level used designations for anti-Complement Factor H (CFH) 抗体

complement factor H , complement factor H related protein 3A4/5G4 , protein beta-1-H , H factor 1 (complement) , H factor 2 (complement) , adrenomedullin binding protein , age-related maculopathy susceptibility 1 , beta-1-H-globulin , beta-1H , factor H , factor H-like 1 , complement component factor H , complement inhibitory factor H , platelet complement factor H , complement regulator factor H

GENE ID SPECIES
457601 Pan troglodytes
553060 Danio rerio
553297 Danio rerio
100399888 Callithrix jacchus
100451270 Pongo abelii
100465619 Ailuropoda melanoleuca
100600041 Nomascus leucogenys
12628 Mus musculus
3075 Homo sapiens
100051358 Equus caballus
155012 Rattus norvegicus
478952 Canis lupus familiaris
100733902 Cavia porcellus
100340175 Oryctolagus cuniculus
397525 Sus scrofa
280816 Bos taurus
429057 Gallus gallus
100174982 Ovis aries
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