anti-Complement Factor H (CFH) 抗体产品概述

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anti-Complement Factor H 抗体 (CFH)
在www.antibodies-online.cn可供264 Complement Factor H (CFH) 抗体的25不同的供货商。 再加上,我们可以发Complement Factor H 试剂盒 (56)Complement Factor H 蛋白 (18)和数多这个蛋白质的别的产品。 总共347 Complement Factor H产品已列进来了。
AHUS1, AMBP1, ARMD4, ARMS1, CFH, CFHL3, fH, FHL1, HF, HF1, HF2, HUS, im:7147412, Mud-1, NOM, Sas-1, Sas1, si:ch211-207o17.2

最受欢迎的抗anti-Complement Factor H (CFH) 抗体


抗Mouse (Murine) Complement Factor H 抗体:

抗Human Complement Factor H 抗体:

抗Rat (Rattus) Complement Factor H 抗体:

所有可销售的anti-Complement Factor H 抗体


引用最多的anti-Complement Factor H 抗体

  1. Human Monoclonal Complement Factor H Primary Antibody for FACS - ABIN2660858 : Ripoche, Day, Harris, Sim: The complete amino acid sequence of human complement factor H. in The Biochemical journal 1988 (PubMed)
    Show all 6 references for 2660858

  2. Human Polyclonal Complement Factor H Primary Antibody for EIA, IF - ABIN951646 : Dieterich, Hammerschmidt, Richter, Skerka, Wallich, Matuschka, Zipfel, Kraiczy: Inadequate binding of immune regulator factor H is associated with sensitivity of Borrelia lusitaniae to human complement. in Infection and immunity 2010 (PubMed)
    Show all 3 references for 951646

  3. Human Polyclonal Complement Factor H Primary Antibody for IF, IHC (p) - ABIN654896 : Scambi, La Verde, De Franceschi, Barausse, Poli, Benedetti, Sorio, Deriu, Roncada, Bortolami, Turrini, Caramaschi, Stranieri, Bambara, Biasi: Comparative proteomic analysis of serum from patients with systemic sclerosis and sclerodermatous GVHD. Evidence of defective function of factor H. in PLoS ONE 2010 (PubMed)
    Show all 2 references for 654896

  4. Human Monoclonal Complement Factor H Primary Antibody for EIA, FACS - ABIN181114 : Alexander, Quigg: The simple design of complement factor H: Looks can be deceiving. in Molecular immunology 2006 (PubMed)
    Show all 2 references for 181114

  5. Horse (Equine) Polyclonal Complement Factor H Primary Antibody for EIA, ID - ABIN113017 : Chung, Liszewski, Nybakken, Davis, Townsend, Fremont, Atkinson, Diamond: West Nile virus nonstructural protein NS1 inhibits complement activation by binding the regulatory protein factor H. in Proceedings of the National Academy of Sciences of the United States of America 2006 (PubMed)

  6. Human Polyclonal Complement Factor H Primary Antibody for ELISA, WB - ABIN250548 : Klein, Zeiss, Chew, Tsai, Sackler, Haynes, Henning, SanGiovanni, Mane, Mayne, Bracken, Ferris, Ott, Barnstable, Hoh: Complement factor H polymorphism in age-related macular degeneration. in Science (New York, N.Y.) 2005 (PubMed)

更多抗Complement Factor H的相互作用对抗体

Chimpanzee Complement Factor H (CFH) interaction partners

  1. interaction between sialylated Neisseria gonorrhoeae and factor H [factor H]

Zebrafish Complement Factor H (CFH) interaction partners

  1. Results report the molecular cloning and identification of complement factor H and complement factor H-like 1-4 (CFHL1 (显示 CFHR1 抗体)-4) in Danio rerio.

Mouse (Murine) Complement Factor H (CFH) interaction partners

  1. VEGF (显示 VEGFA 抗体) inhibition decreases local CFH and other complement regulators in the eye and kidney through reduced VEGFR2 (显示 KDR 抗体)/PKC-alpha (显示 PKCa 抗体)/CREB (显示 CREB1 抗体) signaling.

  2. environmental factors can drive retinal disease in these mice when linked to complement deficits impairing immune function. Both groups of mice had similar levels of retinal amyloid beta accumulation. Consequently there is no direct link between this and inflammation in Cfh(-/-) mice.

  3. absence of plasma CfH conferred susceptibility to glomerulonephritis

  4. This new understanding of the complicated interactions of CFH in AMD (显示 AMD1 抗体)-like pathology provides an improved foundation for the development of targeted therapies for AMD (显示 AMD1 抗体)

  5. data suggest that altered interactions of Cfh with MDA-modified proteins may be relevant in explaining the effects of the Cfh variant.

  6. Cfh and Cfhr2 (显示 CFHR2 抗体) genes are expressed in the mouse outer retina. Only Cfh mRNA was detected in the retinal pigment epithelium, but no protein.

  7. A spectrum of complement dysregulation was modeled on the APOE4 age related macular degeneration mouse model by crossing these mice to complement factor H knockout (cfh-/-) mice to test the impact of excess complement activation.

  8. Data indicate that co-deficiency of factor H (FH) and MASP-1/MASP-3 (显示 MASP1 抗体) did not ameliorate either the plasma Complement C3 (显示 C3 抗体) (C3) activation or glomerular C3 accumulation in FH-deficient mice.

  9. A2E accumulation altered retinal microglial complement regulation by decreasing complement factor H (and increasing complement factor B (显示 CFB 抗体) expression), favoring increased complement activation and lipofuscin deposition in the outer retina.

  10. The exaggerated humoral immune response in CFH(-/-) mice was normalized in CFH(-/-)C5aR (显示 C5AR1 抗体)(-/-) double knockout mice, highlighting the C5aR (显示 C5AR1 抗体) dependence.

Human Complement Factor H (CFH) interaction partners

  1. VEGF (显示 VEGFA 抗体) inhibition decreases local CFH and other complement regulators in the eye and kidney through reduced VEGFR2 (显示 KDR 抗体)/PKC-alpha (显示 PKCa 抗体)/CREB (显示 CREB1 抗体) signaling.

  2. CFH rs1061170 has an important effect on age at onset of MDD in Han Chinese and may therefore be related to early pathogenesis of MDD.

  3. Data suggest that disease-linked mutations in complement factor H (CFH) affect pivotal role of CFH in regulation of complement activation; mutations studied include those linked to atypical hemolytic uremic syndrome and age-related macular degeneration.

  4. Fibrinogen gamma chain (显示 FGG 抗体) and complement factor H were found to be bound as a protein complex in the plasma of a patient with advanced ovarian cancer

  5. Factor I binds C3b-Factor H between Factor H domains 2 and 3 and a reoriented C3b C-terminal domain and docks onto the first scissile bond, while stabilizing its catalytic domain for proteolytic activity.

  6. The VEGF (显示 VEGFA 抗体) haplotype TGA (显示 TBX1 抗体) could be used as a marker for poor visual prognosis in Tunisian patients with neovascular AMD (显示 AMD1 抗体) treated with bevacizumab.

  7. Two protective, low-frequency, non-synonymous variants were significantly associated with a decrease in age-related macular degeneration (AMD (显示 AMD1 抗体))risk: A307V in PELI3 (显示 PELI3 抗体) and N1050Y in CFH .We also identified a strong protective signal for a common variant (rs8056814) near CTRB1 (显示 CTRB1 抗体) associated with a decrease in AMD (显示 AMD1 抗体) risk (logistic regression: OR = 0.71, P = 1.8 x 10-07).

  8. this study shows that RNA interference of factor H in dendritic cells increased alloantigen-specific T-cell proliferation

  9. monomeric CRP (显示 CRP 抗体) (mCRP) but not the pentameric form (pCRP) upregulates IL-8 (显示 IL8 抗体) and CCL2 (显示 CCL2 抗体) levels in retinal pigment epithelial cells. Complement factor H (FH) binds mCRP to dampen its proinflammatory activity. FH from AMD (显示 AMD1 抗体) patients carrying the "risk" His402 polymorphism displays impaired binding to mCRP.

  10. The uromodulin (显示 UMOD 抗体)-CFH interaction enhanced the cofactor activity of CFH for factor I-mediated cleavage of C3b to inactivated C3b.

Pig (Porcine) Complement Factor H (CFH) interaction partners

Complement Factor H (CFH) 抗原简介

Antigen Summary

This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Alternative names and synonyms associated with Complement Factor H (CFH)

  • complement factor H (CFH) 抗体
  • complement factor H (cfh) 抗体
  • complement component factor h (Cfh) 抗体
  • complement factor H (Cfh) 抗体
  • AHUS1 抗体
  • AMBP1 抗体
  • ARMD4 抗体
  • ARMS1 抗体
  • CFH 抗体
  • CFHL3 抗体
  • fH 抗体
  • FHL1 抗体
  • HF 抗体
  • HF1 抗体
  • HF2 抗体
  • HUS 抗体
  • im:7147412 抗体
  • Mud-1 抗体
  • NOM 抗体
  • Sas-1 抗体
  • Sas1 抗体
  • si:ch211-207o17.2 抗体

Protein level used designations for anti-Complement Factor H (CFH) 抗体

complement factor H , complement factor H related protein 3A4/5G4 , protein beta-1-H , H factor 1 (complement) , H factor 2 (complement) , adrenomedullin binding protein , age-related maculopathy susceptibility 1 , beta-1-H-globulin , beta-1H , factor H , factor H-like 1 , complement component factor H , complement inhibitory factor H , platelet complement factor H , complement regulator factor H

457601 Pan troglodytes
553060 Danio rerio
553297 Danio rerio
100399888 Callithrix jacchus
100451270 Pongo abelii
100465619 Ailuropoda melanoleuca
100600041 Nomascus leucogenys
12628 Mus musculus
3075 Homo sapiens
100051358 Equus caballus
155012 Rattus norvegicus
478952 Canis lupus familiaris
100733902 Cavia porcellus
100340175 Oryctolagus cuniculus
397525 Sus scrofa
280816 Bos taurus
429057 Gallus gallus
100174982 Ovis aries
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