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anti-FOXO3 (FOXO3) 抗体产品概述

Full name:
anti-Forkhead Box O3 抗体 (FOXO3)
在www.antibodies-online.cn可供295 Forkhead Box O3 (FOXO3) 抗体的31不同的供货商。 再加上,我们可以发FOXO3 试剂盒 (38)FOXO3 蛋白 (9)和数多这个蛋白质的别的产品。 总共354 FOXO3产品已列进来了。
别名:
1110048B16Rik, 2010203A17Rik, AF6q21, C76856, Fkhr2, Fkhrl1, FKHRL1P2, foxO, FOXO-3, FOXO2, foxO3, FoxO3A, wu:fb50g02, wu:fi33f07, xfoxo3, zgc:92176
列出全部抗体 基因 基因ID UniProt
FOXO3 2309 O43524
FOXO3 56484 Q9WVH4
FOXO3 294515  

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抗Human FOXO3 抗体:

抗Mouse (Murine) FOXO3 抗体:

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引用最多的anti-FOXO3 抗体

  1. Human Polyclonal FOXO3 Primary Antibody for IHC (p), WB - ABIN657229 : Zhuo, Niu, Chen, Xin, Guo, Mao: Vitamin D3 up-regulated protein 1(VDUP1) is regulated by FOXO3A and miR-17-5p at the transcriptional and post-transcriptional levels, respectively, in senescent fibroblasts. in The Journal of biological chemistry 2010 (PubMed)
    Show all 4 references for ABIN657229

  2. Human Polyclonal FOXO3 Primary Antibody for IF, IHC (p) - ABIN658087 : Tudzarova, Trotter, Wollenschlaeger, Mulvey, Godovac-Zimmermann, Williams, Stoeber: Molecular architecture of the DNA replication origin activation checkpoint. in The EMBO journal 2010 (PubMed)
    Show all 4 references for ABIN658087

  3. Human Polyclonal FOXO3 Primary Antibody for EIA, WB - ABIN783540 : Anderson, Viars, Czekay, Cavenee, Arden: Cloning and characterization of three human forkhead genes that comprise an FKHR-like gene subfamily. in Genomics 1998 (PubMed)
    Show all 2 references for ABIN783540

  4. Human Polyclonal FOXO3 Primary Antibody for IHC, ELISA - ABIN1533051 : Mungall, Palmer, Sims, Edwards, Ashurst, Wilming, Jones, Horton, Hunt, Scott, Gilbert, Clamp, Bethel, Milne, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey, Banerjee, Barker et al.: The DNA sequence and analysis of human chromosome 6. ... in Nature 2003 (PubMed)
    Show all 2 references for ABIN1533051

  5. Human Polyclonal FOXO3 Primary Antibody for ChIP, ICC - ABIN4312377 : Sinanoglu, Yener, Ekici, Midi, Aksungar: The protective effects of spirulina in cyclophosphamide induced nephrotoxicity and urotoxicity in rats. in Urology 2012 (PubMed)
    Show all 2 references for ABIN4312377

  6. Human Polyclonal FOXO3 Primary Antibody for IF (p), IHC (p) - ABIN684718 : Morales, Abrigo, Acuña, Santos, Bader, Brandan, Simon, Olguin, Cabrera, Cabello-Verrugio: Angiotensin-(1-7) attenuates disuse skeletal muscle atrophy in mice via its receptor, Mas. in Disease models & mechanisms 2016 (PubMed)

  7. Human Polyclonal FOXO3 Primary Antibody for ELISA, WB - ABIN185248 : Brunet, Bonni, Zigmond, Lin, Juo, Hu, Anderson, Arden, Blenis, Greenberg: Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. in Cell 1999 (PubMed)

  8. Cow (Bovine) Polyclonal FOXO3 Primary Antibody for WB - ABIN2780366 : Pew, Zou, Brickley, Conzen: Glucocorticoid (GC)-mediated down-regulation of urokinase plasminogen activator expression via the serum and GC regulated kinase-1/forkhead box O3a pathway. in Endocrinology 2008 (PubMed)

  9. Cow (Bovine) Polyclonal FOXO3 Primary Antibody for EIA, WB - ABIN374440 : Stefani, Markus, Lin, Pinese, Dawes, Morris: The effect of resveratrol on a cell model of human aging. in Annals of the New York Academy of Sciences 2007 (PubMed)

更多抗FOXO3的相互作用对抗体

Zebrafish Forkhead Box O3 (FOXO3) interaction partners

  1. by modulating hypoxia-inducible factor activity via up-regulation of VHL (显示 VHL 抗体), FOXO3a (foxo3b) plays an important role in survival in response to hypoxic stress.

  2. This study provided novel evidence of FoxO3a in the embryonic neurodevelopment from zebrafish to other mammals.

Human Forkhead Box O3 (FOXO3) interaction partners

  1. Shikonin induces apoptosis in some lung cancer cells via activation of FOXO3a/EGR1 (显示 EGR1 抗体)/SIRT1 (显示 SIRT1 抗体) signaling, and AKT (显示 AKT1 抗体) and p300 (显示 EP300 抗体) negatively regulate this process via Bim (显示 BCL2L11 抗体) upregulation.

  2. the accumulation of reactive oxygen species (ROS (显示 ROS1 抗体)) in cells expressing JAK2V617F compromises the NHE-1 (显示 SLC9A1 抗体)/Bcl-xL (显示 BCL2L1 抗体) deamidation pathway by repressing NHE-1 (显示 SLC9A1 抗体) upregulation in response to DNA damage. hematopoietic stem cells (HSCs), FOXO3A is largely localized within the nuclei despite the presence of JAK2V617F mutation, suggesting that JAK2 (显示 JAK2 抗体)-FOXO signaling has a different effect on progenitors compared with stem cells.

  3. PI3K (显示 PIK3CA 抗体)/AKT (显示 AKT1 抗体)/FoxO3a signaling pathway role in melanoma cells

  4. High FOXO3a and p38 expression could predict the response to cetuximab in patients with CRC harbouring WT KRAS.

  5. Kaplan-Meier survival analysis showed that pancreatic ductal adenocarcinoma patients with negative forkhead box P1 (显示 FOXP1 抗体) and forkhead box O3a expression survived significantly shorter than patients with positive forkhead box P1 (显示 FOXP1 抗体) and forkhead box O3a expression (p = 0.000).

  6. The aims of this study were to quantify the mortality risk for the longevity-associated genotype and to discover the particular cause(s) of death associated with FOXO3 G allele in older Americans of diverse ancestry.

  7. These data suggest that miR (显示 MLXIP 抗体)-592 may promote the progression and metastasis, in part, by targeting FoxO3A in colorectal cancer

  8. This study indicates that CKII (显示 CSNK2A1 抗体) can modulate the intracellular reactive oxygen species level via FoxO3a.

  9. by modulating hypoxia-inducible factor activity via up-regulation of VHL (显示 VHL 抗体), FOXO3a (foxo3b) plays an important role in survival in response to hypoxic stress.

  10. Glucocorticoids treatment was found to rescue FOXO3a expression both in SLE mice and in SLE patients.

Mouse (Murine) Forkhead Box O3 (FOXO3) interaction partners

  1. results indicate that DNA damage accrued as a result of elevated ROS in Foxo3(-/-) mutant HSPC is at least partially reversible

  2. Foxo1 (显示 FOXO1 抗体), Foxo3a, and Foxo4 (显示 FOXO4 抗体) in chondrocytes regulate endochondral bone formation.

  3. Data show that resveratrol reduced mitochondrial reactive oxygen species (mROS) generation by promoting Sirt3 (显示 SIRT3 抗体) enrichment within the mitochondria and subsequent upregulation of FoxO3a-mediated mitochondria gene expression of PGC-1alpha (显示 PPARGC1A 抗体) and SOD2 (显示 SOD2 抗体).

  4. Regulatory loop between FOXO3 and lipid droplets is required for intestinal inflammation.

  5. Maternal diabetes induced caspase 3 (显示 CASP3 抗体)-dependent apoptosis in Sca1 (显示 ATXN1 抗体)(+) cardiac progenitor cells derived from embryonic day 17.5 (E17.5). Both maternal diabetes and high glucose in vitro activated the pro-apoptotic transcription factor, Forkhead O 3a (FoxO3a) via dephosphorylation at threonine 32 (Thr (显示 TRH 抗体)-32) residue.

  6. Mechanistically, exercise-induced nuclear transcription factor FOXO3 binds to the CHCHD4 (显示 CHCHD4 抗体) promoter and represses its expression, preventing the translocation of p53 (显示 TP53 抗体) to the mitochondria and thereby increasing p53 (显示 TP53 抗体) nuclear localization.

  7. Kit inactivation within oocytes also led to premature ovarian failure, albeit via a contrasting phenotype. Despite normal initial complements of primordial follicles, oocytes remained dormant with arrested oocyte maturation. Foxo3 protein localization in the nucleus versus cytoplasm explained both mutant phenotypes.

  8. Glucocorticoids treatment was found to rescue FOXO3a expression both in SLE mice and in SLE patients.

  9. the activation of ERK5 (显示 MAPK7 抗体)-AKT (显示 AKT1 抗体)-FoxO3a signaling pathways by fluid shear stress resulted in a decreased expression of FasL (显示 FASL 抗体) and Bim (显示 BCL2L11 抗体) and an inhibition of caspase-3 (显示 CASP3 抗体) activation, which exerts a protective effect that prevents osteoblasts from apoptosis.

  10. Our results suggest that FoxO3a exerts a negative control over mTOR (显示 FRAP1 抗体), and its loss could result in autophagic defects in LD associated with laforin (显示 EPM2A 抗体) deficiency.

Pig (Porcine) Forkhead Box O3 (FOXO3) interaction partners

  1. These results indicate that myostatin (显示 MSTN 抗体) mediates maternal low protein diet-induced growth retardation, through epigenetic regulation involving FoxO3 and glucocorticoid receptor (显示 NR3C1 抗体) binding to its promoter.

  2. In granulosa cells, cell death is induced by transfection of FOXO3. FOXO3 mRNA in granulosa cells increases during atresia; FOXO3 protein is abundant in granulosa cells of early atretic follicles. (FOXO3 AA sequence homology with human/mouse FOXO3)

  3. PTEN (显示 PTEN 抗体), FOXO3A and PKB (显示 AKT1 抗体) were expressed in a stage- and cell-specific manner during ovarian follicle formation and development in the fetal and neonatal pig.

  4. Primordial oocytes are dormant in prepubertal pigs by a FOXO3-related mechanism to establish a nongrowing oocyte pool in the ovary, and that a transient knockdown of the FOXO3 activates the primordial oocytes to enter the growth phase.

  5. FoxO3a was localized in the granulosa cells of follicles at all stages and was extensively localized in the cytoplasma of the luteinized granulosa cells of corpora lutea

Cow (Bovine) Forkhead Box O3 (FOXO3) interaction partners

  1. NO/protein kinase (显示 CDK7 抗体) G (PKG (显示 PRKG1 抗体))-dependent downregulation of PGC-1 alpha (显示 PPARGC1A 抗体) and the ROS (显示 ROS1 抗体) detoxification system in endothelial cells are mediated by the PI3K/Akt (显示 AKT1 抗体) signaling pathway and subsequent inactivation of transcription factor Foxo3a.

  2. FOXO is a key regulator of ROS (显示 ROS1 抗体)-induced apoptosis in mammalian cells.

FOXO3 抗原简介

Antigen Summary

This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.

Alternative names and synonyms associated with FOXO3

  • forkhead box O3 (FOXO3) 抗体
  • forkhead box O3A (foxo3a) 抗体
  • forkhead box O3 (foxo3) 抗体
  • forkhead box O3 (foxO3) 抗体
  • forkhead box O3 (Foxo3) 抗体
  • 1110048B16Rik 抗体
  • 2010203A17Rik 抗体
  • AF6q21 抗体
  • C76856 抗体
  • Fkhr2 抗体
  • Fkhrl1 抗体
  • FKHRL1P2 抗体
  • foxO 抗体
  • FOXO-3 抗体
  • FOXO2 抗体
  • foxO3 抗体
  • FoxO3A 抗体
  • wu:fb50g02 抗体
  • wu:fi33f07 抗体
  • xfoxo3 抗体
  • zgc:92176 抗体

Protein level used designations for anti-Forkhead Box O3 (FOXO3) 抗体

forkhead box O3 , forkhead box O3A , fb50g02 , fi33f07 , forkhead box O protein , forkhead box protein O3-like , forkhead box protein O3 , forkhead homolog (rhabdomyosarcoma) like 1 , forkhead in rhabdomyosarcoma-like 1 , forkhead, Drosophila, homolog of, in rhabdomyosarcoma-like 1 , forkhead box O3a , forkhead protein FKHR2 , xFoxO3 , forkhead box O3A transcription factor

GENE ID SPECIES
445015 Canis lupus familiaris
494532 Danio rerio
462921 Pan troglodytes
700731 Macaca mulatta
100066558 Equus caballus
100125025 Xenopus (Silurana) tropicalis
100303473 Saccoglossus kowalevskii
100406446 Callithrix jacchus
100451077 Pongo abelii
100600519 Nomascus leucogenys
2309 Homo sapiens
56484 Mus musculus
444992 Xenopus laevis
481954 Canis lupus familiaris
733621 Sus scrofa
294515 Rattus norvegicus
535530 Bos taurus
100713179 Cavia porcellus
421769 Gallus gallus
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