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anti-PKD2 (PKD2) 抗体产品概述

Full name:
anti-Protein Kinase D2 抗体 (PKD2)
在www.antibodies-online.cn可供125 Protein Kinase D2 (PKD2) 抗体的15不同的供货商。 再加上,我们可以发PKD2 试剂盒 (11)PKD2 蛋白 (11)和数多这个蛋白质的别的产品。 总共155 PKD2产品已列进来了。
别名:
AI325941, APKD2, nPKC-D2, Pc-2, PC2, PKD2, PKD4, PRKD2, RGD1308054, TRPP2

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引用最多的anti-PKD2 抗体

  1. Human Polyclonal PKD2 Primary Antibody for IP, WB - ABIN152061 : Liu, Evans, Britton, Zachary: The zinc-finger transcription factor, early growth response 3, mediates VEGF-induced angiogenesis. in Oncogene 2008 (PubMed)
    Show all 8 references for ABIN152061

  2. Human Polyclonal PKD2 Primary Antibody for EIA, IHC (p) - ABIN360330 : Stayner, Zhou: Polycystin channels and kidney disease. in Trends in pharmacological sciences 2001 (PubMed)
    Show all 5 references for ABIN360330

更多抗PKD2的相互作用对抗体

Human Protein Kinase D2 (PKD2) interaction partners

  1. PKD1 (显示 PKD1 抗体) and PKD2 are susceptibility genes for familial intracranial aneurysms in a Japanese population.

  2. Novel PKD2 mutations in Chinese autosomal dominant polycystic kidney disease patients

  3. Two neutral missense PKD2 variants indentified in exon1 c.83G>C (p.R28P) and c.568G>A (p.A190T), which the former segregate with the mutation in affected relatives, and two new intronic and 3'UTR (显示 UTS2R 抗体) variants, c.1548+63C>T and c.*363delA.

  4. this study presents the cryo-EM structure of PKD2 in lipid bilayers at 3.0 A resolution, which establishes PKD2 as a homotetrameric ion channel and provides insight into potential mechanisms for its activation.

  5. PCs expression and p53 (显示 TP53 抗体) activation as a regulator of cell proliferation were further evaluated in vivo and in 69 advanced human carotid atherosclerotic plaques.

  6. PKD2 and RSK1 (显示 RPS6KA1 抗体) regulate integrin beta4 phosphorylation at threonine 1736 to stabilize keratinocyte cell adhesion and its hemidesmosomes.

  7. The coiled-coil domain in the PC2 (显示 KRT6B 抗体) C-terminal forms a stable helix bundle regardless of the presence of Ca(2 (显示 CA2 抗体)+).

  8. Results show that some of the previously reported missense or synonymous mutations in PKD2 gene caused altered pre-mRNA splicing.

  9. PKD2 is a core factor in the formation of this multiprotein complex at the TGN (显示 TG 抗体) that controls constitutive secretion of matrix metalloproteinase (显示 MMP20 抗体) cargo.

  10. Human polycystin-2 transgene dose-dependently rescues autosomal-dominant polycystic kidney disease phenotypes in Pkd2 mutant mice

Mouse (Murine) Protein Kinase D2 (PKD2) interaction partners

  1. Our studies demonstrate that PKD1 (显示 PKD1 抗体)/2 is a key regulator of MVB maturation and exosome secretion, and constitutes a mediator of the DGK alpha (显示 DGKA 抗体) effect on MVB secretory traffic.

  2. Results reveal that whereas protein kinase D1 (显示 PRKD1 抗体) and protein kinase D2 are essential for neuronal polarity, there exists a functional redundancy between the two proteins.

  3. PKD2 acted as an amplification checkpoint for antigen-stimulated digital cytokine responses and translated the differential strength of TCR signaling to determine the number of naive CD8 (显示 CD8A 抗体)(+) T cells that became effector cells.

  4. Protein kinase D2 promotes in vitro osteoclast differentiation and fusion

  5. A bioinformatic screen identified the serine-threonine kinase (显示 CDK4 抗体) protein kinase D2 (PRKD2) as a potential effector of GABP in hematopoietic stem cells

  6. Transcriptional profiling reveals the full consequences of PKD2 loss and maps in detail the selective, but critical, function for PKD2 in signalling by alpha/beta mature TCR complexes in peripheral T-cells.

  7. PKD2 is a common signaling target downstream of various agonist receptors in platelets and G(q)-mediated signals along with calcium and novel PKC (显示 PKC 抗体) isoforms, in particular, PKCdelta (显示 PKCd 抗体) activate PKD2 in platelets.

  8. Data demonstrate that, unlike PKD1 (显示 PKD1 抗体), PKD2 catalytic activity is dispensable for normal embryogenesis.

  9. PKD2, like PKD (显示 PRKD1 抗体), facilitates mitogenesis in 3T3 cells

PKD2 抗原简介

Antigen Summary

The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding different isoforms.

Alternative names and synonyms associated with PKD2

  • protein kinase D2 (PRKD2) 抗体
  • polycystic kidney disease 2 (autosomal dominant) (PKD2) 抗体
  • protein kinase D2 (Prkd2) 抗体
  • AI325941 抗体
  • APKD2 抗体
  • nPKC-D2 抗体
  • Pc-2 抗体
  • PC2 抗体
  • PKD2 抗体
  • PKD4 抗体
  • PRKD2 抗体
  • RGD1308054 抗体
  • TRPP2 抗体

Protein level used designations for anti-Protein Kinase D2 (PKD2) 抗体

protein kinase D2 , serine/threonine-protein kinase D2-like , R48321 , autosomal dominant polycystic kidney disease type II protein , polycystin-2 , polycystwin , transient receptor potential cation channel, subfamily P, member 2 , serine/threonine-protein kinase D2 , nPKC-D2

GENE ID SPECIES
468929 Pan troglodytes
782793 Bos taurus
100407181 Callithrix jacchus
100471375 Ailuropoda melanoleuca
5311 Homo sapiens
25865 Homo sapiens
101540 Mus musculus
292658 Rattus norvegicus
484427 Canis lupus familiaris
100517036 Sus scrofa
100355908 Oryctolagus cuniculus
100717067 Cavia porcellus
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