anti-CCR2 (CCR2) 抗体产品概述

Full name:
anti-Chemokine (C-C Motif) Receptor 2 抗体 (CCR2)
在www.antibodies-online.cn可供302 Chemokine (C-C Motif) Receptor 2 (CCR2) 抗体的24不同的供货商。 再加上,我们可以发CCR2 试剂盒 (15)CCR2 蛋白 (5)和数多这个蛋白质的别的产品。 总共331 CCR2产品已列进来了。
别名:
Cc-ckr-2, CCR-2, Ccr2a, Ccr2b, CD192, Ckr2, Ckr2a, Ckr2b, Cmkbr2, MCP-1-R, mJe-r

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引用最多的anti-CCR2 抗体

  1. Human Monoclonal CCR2 Primary Antibody for FACS - ABIN4895495 : Tsujioka, Imanishi, Ikejima, Kuroi, Takarada, Tanimoto, Kitabata, Okochi, Arita, Ishibashi, Komukai, Kataiwa, Nakamura, Hirata, Tanaka, Akasaka: Impact of heterogeneity of human peripheral blood monocyte subsets on myocardial salvage in patients with primary acute myocardial infarction. in Journal of the American College of Cardiology 2009 (PubMed)
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  2. Human Monoclonal CCR2 Primary Antibody for FACS, IHC - ABIN4899089 : Manley, Caso, Works, Cutler, Zemlyak, Sun, Munhoz, Chang, Sorrells, Ermini, Decker, Bertrand, Dinkel, Steinberg, Sapolsky: Derivation of injury-responsive dendritic cells for acute brain targeting and therapeutic protein delivery in the stroke-injured rat. in PLoS ONE 2013 (PubMed)
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  3. Human Monoclonal CCR2 Primary Antibody for FACS - ABIN4895486 : Shantsila, Wrigley, Tapp, Apostolakis, Montoro-Garcia, Drayson, Lip: Immunophenotypic characterization of human monocyte subsets: possible implications for cardiovascular disease pathophysiology. in Journal of thrombosis and haemostasis : JTH 2011 (PubMed)
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  4. Mouse (Murine) Monoclonal CCR2 Primary Antibody for FACS - ABIN4898197 : Levy, Milikovsky, Baranauskas, Vinogradov, David, Ketzef, Abutbul, Weissberg, Kamintsky, Fleidervish, Friedman, Monsonego: Differential TGF-β Signaling in Glial Subsets Underlies IL-6-Mediated Epileptogenesis in Mice. in Journal of immunology (Baltimore, Md. : 1950) 2015 (PubMed)
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  5. Human Monoclonal CCR2 Primary Antibody for FACS - ABIN4895488 : Dagouassat, Suffee, Hlawaty, Haddad, Charni, Laguillier, Vassy, Martin, Schischmanoff, Gattegno, Oudar, Sutton, Charnaux: Monocyte chemoattractant protein-1 (MCP-1)/CCL2 secreted by hepatic myofibroblasts promotes migration and invasion of human hepatoma cells. in International journal of cancer 2010 (PubMed)
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  6. Human Monoclonal CCR2 Primary Antibody for FACS - ABIN4895489 : Campanelli, Fois, Catarsi, Poletto, Villani, Erba, Maddaluno, Jemos, Salmoiraghi, Guglielmelli, Abbonante, Di Buduo, Balduini, Iurlo, Barosi, Rosti, Massa: Tie2 Expressing Monocytes in the Spleen of Patients with Primary Myelofibrosis. in PLoS ONE 2016 (PubMed)
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  7. Human Polyclonal CCR2 Primary Antibody for WB - ABIN2787666 : Hendrickson, Jacobson, Nelson, Phair, Lautenberger, Johnson, Kingsley, Margolick, Detels, Goedert, OBrien: Host genetic influences on highly active antiretroviral therapy efficacy and AIDS-free survival. in Journal of acquired immune deficiency syndromes (1999) 2008 (PubMed)
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  8. Human Monoclonal CCR2 Primary Antibody for FACS - ABIN4895491 : Kanabar, Tedaldi, Jiang, Nie, Panina, Descroix, Man, Pitchford, Page, Wagner: Base-modified UDP-sugars reduce cell surface levels of P-selectin glycoprotein 1 (PSGL-1) on IL-1β-stimulated human monocytes. in Glycobiology 2016 (PubMed)
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  9. Human Monoclonal CCR2 Primary Antibody for FACS - ABIN4895493 : Falk, Singh, Faber, Nissen, Hviid, Sørensen: CX3CL1/CX3CR1 and CCL2/CCR2 chemokine/chemokine receptor complex in patients with AMD. in PLoS ONE 2014 (PubMed)

  10. Human Polyclonal CCR2 Primary Antibody for FACS, IHC (p) - ABIN152124 : Menasria, Canivet, Piret, Gosselin, Boivin: Both Cerebral and Hematopoietic Deficiencies in CCR2 Result in Uncontrolled Herpes Simplex Virus Infection of the Central Nervous System in Mice. in PLoS ONE 2016 (PubMed)

更多抗CCR2的相互作用对抗体

Human Chemokine (C-C Motif) Receptor 2 (CCR2) interaction partners

  1. The CCR2 (+190 G/A) GG genotype frequencies for patients were significantly higher in the stage III-IV cancer group ( p = 0.036), and A allele carriers were significantly higher in the stage I-II ovarian cancer group.

  2. tumor-promoting role for CCL2 acting through CCR2 on the tumor microenvironment

  3. The findings of the work indicate a role for Galphaq (显示 GNAQ 抗体) and/or Galpha14 and in CCR2a/CCR2b-stimulated Rho A (显示 RHOA 抗体) GTPase (显示 RACGAP1 抗体)-mediated serum response factor activation.

  4. Endogenous TRAIL/TRAIL-R-mediated CCL2 (显示 CCL2 抗体) secretion promotes accumulation of tumor-supportive immune cells in the cancer microenvironment.

  5. CCL2 (显示 CCL2 抗体)/CCR2 axis is expressed in the majority of monocytoid Acute myeloid leukemia (显示 BCL11A 抗体) blasts

  6. CCR2B and beta2AR (显示 ADRB2 抗体) signals to FLNa (显示 FLNA 抗体) to stimulate its endocytosis and recycling to the plasma membrane.

  7. this study shows that CYTL1 (显示 CYTL1 抗体) possesses chemotactic activity and demonstrates that its functional receptor is CCR2B

  8. PCSK9 regulates monocyte CCR2 expression and chemotaxis.

  9. CCR2-targeted therapy with PF-04136309 in combination with FOLFIRINOX is safe and tolerable

  10. Binding of J113863 to CCR2 or CCR5 also induced the recruitment of beta-arrestin 2, whereas UCB35625 did not. UCB35625 induced the chemotaxis of L1.2 cells expressing CCR2 or CCR5. In contrast, J113863 induced the migration of L1.2-CCR2 cells but antagonized the chemokine-induced migration of L1.2-CCR5 cells.

Mouse (Murine) Chemokine (C-C Motif) Receptor 2 (CCR2) interaction partners

  1. in vitro and in vivo results show that CCR2 intrinsically mediates the expression of inflammatory T cell cytokines, and its absence on T cells results in attenuated colitis progression

  2. tumor-promoting role for CCL2 acting through CCR2 on the tumor microenvironment

  3. CCR2 expression on bone marrow-derived cells, likely macrophages, is essential to muscle regeneration independent of TLR signaling, aging, and sex.

  4. we demonstrated that CX3CR1 (显示 CX3CR1 抗体)(Lo)CCR2(Hi) monocytes were recruited to the GBM, where they transitioned to CX3CR1 (显示 CX3CR1 抗体)(Hi)CCR2(Lo) macrophages and CX3CR1 (显示 CX3CR1 抗体)(Hi)CCR2(-) microglia-like cells. Infiltrating macrophages/monocytes constituted approximately 85% of the total TAM (显示 CCNA1 抗体) population, with resident microglia accounting for the approximately 15% remaining.

  5. we characterized a novel regulatory network in macrophages, in which CCR2 activates PI3K-AKT (显示 AKT1 抗体)-mTOR (显示 FRAP1 抗体) signaling to mediate HIF-1alpha (显示 HIF1A 抗体) expression, which then drives VEGF-C (显示 VEGFC 抗体) expression to promote lymphangiogenesis.

  6. CXCR4 (显示 CXCR4 抗体), CCR2, and CX3CR1 (显示 CX3CR1 抗体) direct dendritic cell precursors from the bone marrow to the lung differentially.

  7. The findings suggest that CCR2 deficiency does not provide a sustained benefit and that Ly6C(low) macrophages may contribute to the progressive fibrosis and dysfunction of mdx (显示 DMD 抗体)(5cv) diaphragm.

  8. In Ccr2(-/-) mice, a damaged microglia recruitment was shown in retina and this could protect the visual function in electroretinogram and alleviate the photoreceptor apoptosis.

  9. This study establishes ECL1i as the first allosteric inhibitor of CCR2 with functional selectivity.

  10. the individual and combined actions of CCL2 (显示 CCL2 抗体)/CCR2 and CX3CL1 (显示 CX3CL1 抗体)/CX3CR1 (显示 CX3CR1 抗体) in hypoxia-induced pulmonary hypertension in mice, is reported.

CCR2 抗原简介

Antigen Summary

This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene.

Alternative names and synonyms associated with CCR2

  • chemokine (C-C motif) receptor 2 (CCR2) 抗体
  • chemokine (C-C motif) receptor 2 (Ccr2) 抗体
  • Cc-ckr-2 抗体
  • CCR-2 抗体
  • Ccr2a 抗体
  • Ccr2b 抗体
  • CD192 抗体
  • Ckr2 抗体
  • Ckr2a 抗体
  • Ckr2b 抗体
  • Cmkbr2 抗体
  • MCP-1-R 抗体
  • mJe-r 抗体

Protein level used designations for CCR2

C-C chemokine receptor type 2 , MCP-1 receptor , monocyte chemoattractant protein 1 receptor , monocyte chemotactic protein 1 receptor , C-C CHEMOKINE RECEPTOR TYPE 2 (C-C CKR-2) (CC-CKR-2) (CCR-2) (CCR2) (JE/FIC RECEPTOR) (MCP-1 RECEPTOR) , C-C CKR-2 , CCR-2 , JE/FIC receptor , MIP-1 alphaR , chemoattractant protein-1 receptor , chemokine (C-C) receptor 2 , CC-CKR-2 , chemokine receptor CCR2 , MCP-1-R , chemokine receptor

GENE ID SPECIES
729230 Homo sapiens
12772 Mus musculus
60463 Rattus norvegicus
484790 Canis lupus familiaris
574098 Macaca mulatta
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