anti-BCL2L1 (BCL2L1) 抗体产品概述

Full name:
anti-BCL2-Like 1 抗体 (BCL2L1)
在www.antibodies-online.cn可供516 BCL2-Like 1 (BCL2L1) 抗体的37不同的供货商。 再加上,我们可以发BCL2L1 试剂盒 (22)BCL2L1 蛋白 (17)和数多这个蛋白质的别的产品。 总共579 BCL2L1产品已列进来了。
别名:
Bcl(X)L, bcl-X, bcl-x(l), bcl-xl, BCL-XL/S, Bcl-Xs, Bcl2l, BCL2L1, Bclx, BCLXL, BCLXS, PPP1R52, xR11
列出全部抗体 基因 基因ID UniProt
BCL2L1 60480  
BCL2L1 598 Q07817
BCL2L1 24888 P53563

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引用最多的anti-BCL2L1 抗体

  1. Human Polyclonal BCL2L1 Primary Antibody for ELISA, IF (p) - ABIN675129 : Wang, Ma, Su: NF-?B pathway contributes to cadmium-induced apoptosis of porcine granulosa cells. in Biological trace element research 2013 (PubMed)
    Show all 5 references for 675129

  2. Human Monoclonal BCL2L1 Primary Antibody for FACS, IF - ABIN180627 : Hsu, Youle: Nonionic detergents induce dimerization among members of the Bcl-2 family. in The Journal of biological chemistry 1997 (PubMed)
    Show all 3 references for 180627

  3. Human Polyclonal BCL2L1 Primary Antibody for IHC, ELISA - ABIN1531788 : Cheng, Levine, Boise, Thompson, Hardwick: Bax-independent inhibition of apoptosis by Bcl-XL. in Nature 1996 (PubMed)
    Show all 3 references for 1531788

  4. Human Polyclonal BCL2L1 Primary Antibody for IP, WB - ABIN223050 : Cordiali-Fei, Ardigo, Mastroianni, Giuliani, D Agosto, Bordignon, Trento, Vento, Berardesca: Serum cytokines and biohumoral immunological characterization of psoriatic patients in long term etanercept treatment. in International journal of immunopathology and pharmacology 2008 (PubMed)
    Show all 3 references for 223050

  5. Human Polyclonal BCL2L1 Primary Antibody for IHC, ELISA - ABIN1532818 : Sattler, Liang, Nettesheim, Meadows, Harlan, Eberstadt, Yoon, Shuker, Chang, Minn, Thompson, Fesik: Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis. in Science (New York, N.Y.) 1997 (PubMed)
    Show all 3 references for 1532818

  6. Human Polyclonal BCL2L1 Primary Antibody for IHC, ELISA - ABIN1533140 : Boise, González-García, Postema, Ding, Lindsten, Turka, Mao, Nuñez, Thompson: bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death. in Cell 1993 (PubMed)
    Show all 2 references for 1533140

  7. Human Polyclonal BCL2L1 Primary Antibody for IHC, ELISA - ABIN1532107 : Deloukas, Matthews, Ashurst, Burton, Gilbert, Jones, Stavrides, Almeida, Babbage, Bagguley, Bailey, Barlow, Bates, Beard, Beare, Beasley, Bird, Blakey, Bridgeman, Brown, Buck, Burrill, Butler, Carder et al.: The DNA sequence and comparative analysis of human chromosome 20. ... in Nature 2002 (PubMed)
    Show all 2 references for 1532107

  8. Cow (Bovine) Polyclonal BCL2L1 Primary Antibody for WB - ABIN2774598 : Bachelor, Bowden: Ultraviolet A-induced modulation of Bcl-XL by p38 MAPK in human keratinocytes: post-transcriptional regulation through the 3'-untranslated region. in The Journal of biological chemistry 2004 (PubMed)

  9. Cow (Bovine) Polyclonal BCL2L1 Primary Antibody for WB - ABIN2792119 : Xu, Xu, Palmer, Reed: BI-1 regulates endoplasmic reticulum Ca2+ homeostasis downstream of Bcl-2 family proteins. in The Journal of biological chemistry 2008 (PubMed)

  10. Cow (Bovine) Polyclonal BCL2L1 Primary Antibody for WB - ABIN2779336 : ONeill, Manion, Maguire, Hockenbery: BCL-XL dimerization by three-dimensional domain swapping. in Journal of molecular biology 2006 (PubMed)

更多抗BCL2L1的相互作用对抗体

Mouse (Murine) BCL2-Like 1 (BCL2L1) interaction partners

  1. Bcl-xL deficiency induced apoptosis in a select population of differentiated neurons and led to severe neurobehavioral abnormalities.

  2. loss of PUMA (显示 BBC3 抗体) had no impact on the loss of platelets caused by loss of BCL-XL. It therefore remains to be established whether other BH3-only (显示 BBC3 抗体) proteins play a critical role in induction of apoptosis in platelets or whether their death is controlled solely by the interactions between BCL-XL with BAK (显示 BAK1 抗体) and BAX (显示 BAX 抗体).

  3. MLF1 (显示 MLF1 抗体) is negatively regulated by 14-3-3 (显示 YWHAQ 抗体) via binding to, and blocking, MLF1 (显示 MLF1 抗体)'s Bcl-2 (显示 BCL2 抗体) homology domain 3 and thereby preventing Bcl-XL from associating with MLF1 (显示 MLF1 抗体).

  4. Genetic and pharmacological inhibition of BCL-W (显示 BCL2L2 抗体) and BCL-XL causes directed elimination of senescent cells.

  5. Valproic acid sensitized TRAIL-resistant papillary thyroid carcinoma cells to apoptotic cell death through involvement of Nrf2 (显示 NFE2L2 抗体) and Bcl-xL.

  6. The influence of chronic ethanol consumption on the expression of the Bdnf (显示 BDNF 抗体), Bax (显示 BAX 抗体), Bcl-xL, and CASP3 (显示 CASP3 抗体) genes was studied in the brain structures of B6-1473C (C/C) and B6-1473G (G/G) mice that had been obtained on the base of the C57BL/6 strain.

  7. despite its role in Bax (显示 BAX 抗体) inhibition, Bcl-xL also primes mitochondria to permeabilization and cytochrome c (显示 CYCS 抗体) release.

  8. These findings indicate that eosinophil survival is largely regulated by betac chain-induced NF-kappaB (显示 NFKB1 抗体) activation and subsequent induction of Bcl-x

  9. these data indicate that beta-cell apoptosis is, in part, attributable to the modulation of 5'SS selection in the Bcl-x pre-mRNA by bioactive lipids modulated by iPLA2beta (显示 PLA2G6 抗体).

  10. only loss of both Bclx alleles markedly forestalled tumorigenesis, loss of a single Bim (显示 BCL2L11 抗体) allele overcame this blockade.

Human BCL2-Like 1 (BCL2L1) interaction partners

  1. BC200 knockout suppresses tumor cell growth in vitro and in vivo by expression of the pro-apoptotic Bcl-xS isoform.

  2. Bcl-xL inhibits GAS-induced autophagy directly by suppressing autophagosome-lysosome fusion and indirectly by suppressing GAS internalization via interaction with Beclin 1 (显示 BECN1 抗体)-UVRAG (显示 UVRAG 抗体).

  3. The combination of 2-deoxyglucose (2-DG) and ABT-199 initiated cell death through the reduction of myeloid cell leukemia sequence 1 protein (Mcl-1 (显示 MCL1 抗体)) expression and c-Jun N-terminal kinase 1 (JNK1 (显示 MAPK8 抗体)) activation and subsequent Bcl-xL protein degradation.

  4. Bcl-xL is an exosomal caspase-3 (显示 CASP3 抗体) substrate and that this processing is required for the uptake of exosomes by recipient cells.

  5. dynamic Bcl-xL(S49) and (S62) phosphorylation/dephosphorylation cycles are important in the maintenance of chromosome integrity during mitosis in normal cells

  6. in addition to MCL-1 (显示 MCL1 抗体), BCL-XL is heterogeneously expressed in HMCLs and patient samples. The expression profile of BCL-XL relative to BCL-2 (显示 BCL2 抗体) and MCL-1 (显示 MCL1 抗体) may be an important predictor of response to venetoclax sensitivity as a monotherapy and in combination with bortezomib.

  7. Mono treatment with lexatumumab was not sufficient to induce apoptosis in pancreatic cancer cells, whereas focal adhesion kinase inhibitor PF573228 significantly sensitized lexatumumab-induced apoptosis. Western blotting analysis revealed that lexatumumab and PF573228 combination treatment increased death receptor 5 (显示 TNFRSF10B 抗体) but decreased Bcl-xL expression.

  8. Reduced lifetimes of the donor were partially restored by coexpression of HIF-1alpha (显示 HIF1A 抗体) or Bcl-xL, binding proteins of IPAS (显示 HIF3A 抗体) in the nucleus and mitochondria, respectively.

  9. mechanistic studies, inhibition of SRC (显示 SRC 抗体) and PKCdelta (显示 PKCd 抗体) completely ablated the ability of MDA-7/IL-24 (显示 IL24 抗体) to reduce the Bcl-x(L)/(s) mRNA ratio and cell viability. These findings show that Bcl-x(s) expression is an important mediator of MDA-7/IL-24 (显示 IL24 抗体)-induced cytotoxicity requiring the SRC (显示 SRC 抗体)/PKCdelta (显示 PKCd 抗体) signaling axis in NSCLC cells.

  10. Resistance induced in newly formed cancer stem cells is mediated by the anti-apoptotic molecule BCL-XL and inhibition of BCL-XL with the BH3 mimetic ABT-737 sensitizes these cancer cells toward chemotherapy.

Pig (Porcine) BCL2-Like 1 (BCL2L1) interaction partners

  1. interleukin-6 (显示 IL6 抗体), endothelin ET-1 (显示 EDN1 抗体), and apoptotic Bak (显示 BAK1 抗体) and Bcl-XL genes have roles in small bowel transplantation, in a swine model of ischemia and reperfusion injury

  2. Bcl-xL was significantly decreased in haploid parthenotes compared with the diploid parthenotes. These results suggest that the haploid state affects apoptosis-related gene expression which results in increased apoptosis

  3. CONCLUSION(S): (1) Apoptosis is involved in follicular atresia; (2) Bcl-2 (显示 BCL2 抗体) is induced by warm ischemia; and (3) cryopreservation insult does not alter the apoptotic signals with short tissue preparation time.

  4. Bcl-Xl deamidation and methylation has a role in protein isoaspartate methyltransferase prevention of apoptosis induced by oxidative stress in endothelial cells

  5. Data show that cysteine significantly reduced the expression of pro-inflammatory cytokines, including TNF-alpha (显示 TNF 抗体), IL-6 (显示 IL6 抗体), IL-12p40, IL-1beta (显示 IL1B 抗体), and resulted in increased expression of the apoptosis initiator caspase-8 (显示 CASP8 抗体) and bcl2L1.

Cow (Bovine) BCL2-Like 1 (BCL2L1) interaction partners

  1. amplification and characterization of partial regions of exons 2 and 3 of the bovine BCL2L1 gene

  2. Data show that Bcl-x(L) expression is increased in the pulmonary artery undergoing chronic pulmonary vascular remodeling.

Rabbit BCL2-Like 1 (BCL2L1) interaction partners

  1. This study leads to conclude that BCLXL peak expression at the zygotic genome activation phase may be a requirement for embryo development

  2. In this study evidence is provided that exogenous PGF2alpha differentially modulates luteal expression of BCL2L1 transcripts and protein depending on luteal stage.

Xenopus laevis BCL2-Like 1 (BCL2L1) interaction partners

  1. repression of radiation-induced apoptosis by overexpression of Bcl-xL during embryonic development depends upon the timing of its expression and post-translational events that enable the protein to become effective

BCL2L1 抗原简介

Antigen Summary

The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator.

Alternative names and synonyms associated with BCL2L1

  • BCL2-like 1 (bcl2l1) 抗体
  • BCL2-like 1 (BCL2L1) 抗体
  • BCL2-like 1 (LOC100224900) 抗体
  • transgene insertion 2, Craig B Thompson (Tg(BCL2L1)2Cbt) 抗体
  • BCL2-like 1 (Bcl2l1) 抗体
  • Bcl2-like 1 (Bcl2l1) 抗体
  • Bcl(X)L 抗体
  • bcl-X 抗体
  • bcl-x(l) 抗体
  • bcl-xl 抗体
  • BCL-XL/S 抗体
  • Bcl-Xs 抗体
  • Bcl2l 抗体
  • BCL2L1 抗体
  • Bclx 抗体
  • BCLXL 抗体
  • BCLXS 抗体
  • PPP1R52 抗体
  • xR11 抗体

Protein level used designations for anti-BCL2-Like 1 (BCL2L1) 抗体

BCL2-like 1 , apoptosis regulator Bcl-X , bcl-2-like protein 1 , protein phosphatase 1, regulatory subunit 52 , B-cell leukemia/lymphoma x , anti-apoptosis regulatory protein , bcl2-L-1 , B cell lymphoma 2 like , B cell lymphoma like X , anti-apoptotic Bcl-xL , BCL2-like protein 1 , Bcl-X , BCLX protein , apoptosis regulator R11

GENE ID SPECIES
447991 Xenopus (Silurana) tropicalis
458156 Pan troglodytes
100224900 Taeniopygia guttata
60480 Mus musculus
598 Homo sapiens
12048 Mus musculus
24888 Rattus norvegicus
397536 Sus scrofa
403618 Canis lupus familiaris
282152 Bos taurus
100008875 Oryctolagus cuniculus
493701 Felis catus
443061 Ovis aries
373954 Gallus gallus
398251 Xenopus laevis
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