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LGR5 抗体 (N-Term)

This 兔 多克隆 antibody specifically detects LGR5 in WB. It exhibits reactivity toward 小鼠. It has been mentioned in 4+ publications
产品编号 ABIN389215
发货至: 中国
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Quick Overview for LGR5 抗体 (N-Term) (ABIN389215)

抗原

See all LGR5 抗体
LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))

适用

  • 116
  • 69
  • 54
  • 1
  • 1
小鼠

宿主

  • 94
  • 20
  • 3

克隆类型

  • 73
  • 44
多克隆

标记

  • 58
  • 5
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  • 2
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  • 1
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This LGR5 antibody is un-conjugated

应用范围

  • 81
  • 51
  • 25
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  • 15
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  • 9
  • 7
  • 1
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  • 1
Western Blotting (WB)

克隆位点

RB14764
  • 抗原表位

    • 17
    • 15
    • 6
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    • 3
    • 3
    • 2
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    • 1
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    • 1
    • 1
    • 1
    AA 238-270, N-Term

    预测反应

    H

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This LGR5/GPR49 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 238-270 amino acids from the N-terminal region of human LGR5/GPR49.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Usui, Sakurai, Enjoji, Kawasaki, Umata, Ohama, Fujiwara, Yabe, Tsuji, Yamawaki, Hazama, Takenouchi, Nakajima, Tsunedomi, Suzuki, Nagano, Sato: "Establishment of a Novel Model for Anticancer Drug Resistance in Three-Dimensional Primary Culture of Tumor Microenvironment." in: Stem cells international, Vol. 2016, pp. 7053872, (2017) (PubMed).

    Fender, Nutter, Bertrand, Sigounas: "Notch-1 Promotes Stemness and Epithelial to Mesenchymal Transition in Colorectal Cancer." in: Journal of cellular biochemistry, (2015) (PubMed).

    Jardé, Kass, Staples, Lescesen, Carne, Oliva, McMurrick, Abud: "ERBB3 Positively Correlates with Intestinal Stem Cell Markers but Marks a Distinct Non Proliferative Cell Population in Colorectal Cancer." in: PLoS ONE, Vol. 10, Issue 9, pp. e0138336, (2015) (PubMed).

    Kanwar, Yu, Nautiyal, Patel, Majumdar: "The Wnt/beta-catenin pathway regulates growth and maintenance of colonospheres." in: Molecular cancer, Vol. 9, pp. 212, (2010) (PubMed).

  • 抗原

    LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))

    别名

    LGR5/GPR49

    背景

    LGR5/GPR49 is an orphan receptor. It may be an important receptor for signals controlling growth and differentiation of specific embryonic tissues.

    分子量

    99998

    基因ID

    8549

    NCBI登录号

    NP_001264155, NP_003658

    UniProt

    O75473

    途径

    WNT signaling
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