LGR5 抗体 (N-Term)
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北京 101111
Quick Overview for LGR5 抗体 (N-Term) (ABIN389215)
抗原
See all LGR5 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 238-270, N-Term
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预测反应
- H
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This LGR5/GPR49 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 238-270 amino acids from the N-terminal region of human LGR5/GPR49.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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: "Establishment of a Novel Model for Anticancer Drug Resistance in Three-Dimensional Primary Culture of Tumor Microenvironment." in: Stem cells international, Vol. 2016, pp. 7053872, (2017) (PubMed).
: "Notch-1 Promotes Stemness and Epithelial to Mesenchymal Transition in Colorectal Cancer." in: Journal of cellular biochemistry, (2015) (PubMed).
: "ERBB3 Positively Correlates with Intestinal Stem Cell Markers but Marks a Distinct Non Proliferative Cell Population in Colorectal Cancer." in: PLoS ONE, Vol. 10, Issue 9, pp. e0138336, (2015) (PubMed).
: "The Wnt/beta-catenin pathway regulates growth and maintenance of colonospheres." in: Molecular cancer, Vol. 9, pp. 212, (2010) (PubMed).
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- LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))
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别名
- LGR5/GPR49
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背景
- LGR5/GPR49 is an orphan receptor. It may be an important receptor for signals controlling growth and differentiation of specific embryonic tissues.
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分子量
- 99998
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基因ID
- 8549
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NCBI登录号
- NP_001264155, NP_003658
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UniProt
- O75473
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途径
- WNT signaling
抗原
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