HSF1 抗体 (Sumoylation Site)
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Quick Overview for HSF1 抗体 (Sumoylation Site) (ABIN389069)
抗原
See all HSF1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 278-309, Sumoylation Site
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预测反应
- B
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This HSF1 Sumoylation Site antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 278-309 amino acids from human HSF1 Sumoylation Site.
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亚型
- Ig Fraction
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应用备注
- IF: 1:10~50. WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- HSF1 (Heat Shock Factor Protein 1 (HSF1))
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别名
- HSF1
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背景
- Heat shock transcription factor 1 (HSF1) mediates the induction of heat shock protein gene expression in cells exposed to elevated temperature and other stress conditions. In response to stress, HSF1 acquires DNA-binding ability and localizes to nuclear stress granules. SUMO modification of HSF1 converts HSF1 to the DNA-binding form. HSF1 colocalizes with SUMO-1 in nuclear stress granules, which is prevented by mutation of the HSF1 lysine targeted for sumoylation.
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分子量
- 57260
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基因ID
- 3297
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NCBI登录号
- NP_005517
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UniProt
- Q00613
抗原
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