我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

Calnexin 抗体 (C-Term)

Name: Calnexin 抗体 (C-Term)
SKU: ABIN1607882
Availability: OutOfStock

CANX 适用: 人, 小鼠, 大鼠, 小鸡, 灵长类 WB, IHC, ELISA, FM 宿主: 兔 Polyclonal unconjugated

产品编号 ABIN1607882

Supplier Product No.: 600-401-j15

发货至: 中国

Datasheet as PDF

抗原 See all Calnexin (CANX) 抗体

Calnexin (CANX)
抗原表位
47

17

12

7

5

5

5

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
C-Term
适用
118

73

72

47

30

28

28

26

26

22

22

22

20

20

19

6

3

2

2

1

1

1

1

1

1

1
人, 小鼠, 大鼠, 小鸡, 灵长类
宿主
120

24

7
兔
Compatible Secondaries
克隆类型
119

33
多克隆
标记
69

8

7

5

5

4

4

4

3

3

3

3

3

3

3

3

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This Calnexin antibody is un-conjugated
应用范围
121

80

57

56

39

27

25

24

20

14

13

9

8

4

3

3

2

2

2

2

1

1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Fluorescence Microscopy (FM)

Supplier Product No.

600-401-j15

Supplier

Rockland

原理

Calnexin Antibody

交叉反应（详细）

This antibody is specific towards calnexin.

产品特性

Synonyms: rabbit anti-calnexin antibody, CANX, Major histocompatibility complex class I antigen-binding protein p88, p90, IP90

纯化方法

Anti-Calnexin was affinity purified from monospecific antiserum by immunoaffinity chromatography.

过滤

Sterile filtered

免疫原

Immunogen: Calnexin affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to the C-terminus of human Calnexin.
Immunogen Type: Conjugated Peptide

Top Product

Discover our top product CANX Primary Antibody
anti-Calnexin (CANX) (C-Term) antibody
CANX 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, Pig, 猴, Hamster, 绵羊, 小鸡, Avian, 马, 山羊, Cat, 驴 WB, IF, IHC (p), IHC (fro) 宿主: 山羊 Polyclonal unconjugated

anti-Calnexin (CANX) (C-Term) antibody
CANX 适用: 犬 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Calnexin (CANX) (Internal Region) antibody
CANX 适用: 人, 小鼠, 大鼠 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Calnexin (CANX) (AA 263-482) antibody
CANX 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Calnexin (CANX) (AA 504-592) antibody
CANX 适用: 人 WB, IF, ELISA, IHC (p), PLA 宿主: 小鼠 Monoclonal 1D4 unconjugated

anti-Calnexin (CANX) (AA 1-300), (N-Term) antibody
CANX 适用: 人 WB, IHC, ELISA, Coat, StM 宿主: 小鼠 Monoclonal CANX-1541 unconjugated

anti-Calnexin (CANX) (AA 239-461) antibody
CANX 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Calnexin (CANX) (AA 239-461) antibody
CANX 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C3 unconjugated

anti-Calnexin (CANX) (AA 1-300), (N-Term) antibody
CANX 适用: 人 WB, IHC, ELISA, Coat, StM 宿主: 小鼠 Monoclonal CANX-1543 unconjugated

anti-Calnexin (CANX) (C-Term) antibody
CANX 适用: 犬 WB, IHC, IF, IP, FACS, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Immunohistochemistry Dilution: 1:100-1:500
Application Note: Anti-Calnexin antibody is useful for ELISA and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~67.7 kDa corresponding to the appropriate cell lysate or extract.
Western Blot Dilution: 0.2 μg/mL
ELISA Dilution: 1:20,000 - 1:60,000
IF Microscopy Dilution: 1:100-1:500
Other: User Optimized

限制

仅限研究用
状态

Liquid

浓度

0.34 mg/mL

缓冲液

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 50 % (v/v) Glycerol
Preservative: None

储存液

Without preservative

储存条件

4 °C,-20 °C

储存方法

Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

有效期

6 months
抗原

Calnexin (CANX)

别名

CANX (CANX 产品)

背景

Background: Calnexin, also referred to as IP90, p88 and p90, is an ~90 kDa integral membrane protein of the endoplasmic reticulum (ER). Many resident ER proteins act as molecular chaperones and participate in the proper folding of polypeptides and their assembly into multisubunit proteins. Studies indicate that calnexin associates with the major histocompatibility complex (MHC) class I heavy chains, partial complexes of the T cell receptor and B cell membrane immunoglobulin, but not with completed receptor complexes. It has been shown that calnexin is a chaperone that retains incompletely or improperly folded proteins in the ER. The sequence Lys-Asp-Glu-Leu (KDEL) or a closely related sequence, is present at the carboxy-terminus of soluble ER resident proteins such as GRP 78 and GRP 94 and protein disulfide isomerase. Integral membrane ER resident proteins, like calnexin, often lack this KDEL sequence but contain positively charged cytosolic residues that ensure ER retention. Calnexin contains a large ER luminal domain (461 amino acids), a transmembrane segment (22 amino acids), and a cytoplasmic tail (89 amino acids). These features distinguish calnexin from soluble ER chaperones that cannot interact with the transmembrane and cytosolic domains of integral membrane proteins. The amino acid sequence of calnexin is highly conserved among species, and shares regions of high sequence homology with calreticulin. Anti-Calnexin antibody is ideal for researchers interested in ER Markers, Neuroscience, and Vision research.

基因ID

821

NCBI登录号

NP_001019820

UniProt

P27824

途径

MAPK Pathway, Thyroid Hormone Synthesis