HLA B7 抗体 (FITC)
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Quick Overview for HLA B7 抗体 (FITC) (ABIN118933)
抗原
See all HLA B7 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody recognises the Human HLA-B7 antigen and does not cross-react with HLA-B27 or other related HLA antigens. It can be used to distinguish true HLA-B27 positives from false HLA-B27 positives (i.e. HLA-B7 positive) in the investigation of such diseases as ankylosing spondylitis and anterior uveitis.
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交叉反应 (详细)
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Species reactivity (expected):Cynomolgus monkey.
Species reactivity (tested):Human. -
纯化方法
- Affinity Chromatography on Protein G
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免疫原
- Papain solubilized HLA-B7 antigen.
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亚型
- IgG1
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应用备注
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Flow cytometry: use 10 μL of neat - 1/10 diluted antibody to label 1x10^6 cells in 100 μL whole blood.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, pH 7.4, 0.09 % Sodium Azide, 1 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- HLA B7 (HLA Class I B7 Alpha (HLA B7))
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背景
- HLA B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta 2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa. Hundreds of HLA B alleles have been described. The HLA B gene is part of the human HLA complex on chromosome 6 and there are a large number of variant alleles of this gene.Synonyms: B-7 alpha chain, HLA class I histocompatibility antigen, HLAB, MHC class I antigen B7
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基因ID
- 3106
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NCBI登录号
- NP_005505
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UniProt
- P01889
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途径
- Human Leukocyte Antigen (HLA) in Adaptive Immune Response
抗原
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