Integrin beta 2 抗体 (PE)
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- 抗原 See all Integrin beta 2 (ITGB2) 抗体
- Integrin beta 2 (ITGB2)
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适用
- 人, 犬
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This Integrin beta 2 antibody is conjugated to PE
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应用范围
- Flow Cytometry (FACS)
- 特异性
- YFC118.3 was clustered at the Fourth International Workshop on Leucocyte Differentiation Antigen as recognising the CD18 antigen. The main cellular reactivity of antibody YFC 118.3 is a strong reactivity with Leucocytes (platelets negative). YFC118.3 blocks homotypic adhesion and other lymphocyte functions which involve the LFA-1 antigen.
- 纯化方法
- Affinity chromatography on Protein G
- 免疫原
- Human neutrophils. Spleen cells from immunised LOU rats were fused with cells of the Y3/Ag.1.2.3 rat myeloma cell line.
- 克隆位点
- YFC118-3
- 亚型
- IgG2b
- Top Product
- Discover our top product ITGB2 Primary Antibody
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- 应用备注
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Flow cytometry: Use 10 μL of neat antibody to label 100 μL whole blood or 10^6 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 溶解方式
- SM1076R: Restore with 1 mL distilled water. SM1076RT: Restore with 25 μL distilled water.
- 缓冲液
- PBS, pH 7.2 containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Aliquot and store antibody and control at -20 °C.
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- 抗原
- Integrin beta 2 (ITGB2)
- 别名
- CD18 / ITGB2 (ITGB2 产品)
- 别名
- CD18 antibody, LAD antibody, LCAMB antibody, LFA-1 antibody, MAC-1 antibody, MF17 antibody, MFI7 antibody, 2E6 antibody, AI528527 antibody, Cd18 antibody, Lfa1 antibody, ITGB2 antibody, itgb2 antibody, itgb2-a antibody, itgb2-b antibody, integrin subunit beta 2 antibody, integrin beta 2 antibody, integrin subunit beta 2 S homeolog antibody, ITGB2 antibody, Itgb2 antibody, itgb2.S antibody
- 背景
- The CD18 antigen is an integral membrane glycoprotein of 95kD molecular weight - known as the b chain, of the LFA-1 complex. The CD18 antigen is non-covalently linked to CD11a, b, c molecules. The CD18 Molecule is the receptor for ICAM-1 and is thus important for cell adhesion.Synonyms: 95 subunit beta, Cell surface adhesion glycoproteins LFA-1/CR3/p150, Complement receptor C3 subunit beta, Integrin beta-2, MFI7
- 基因ID
- 3689
- NCBI登录号
- NP_000202
- UniProt
- P05107
- 途径
- NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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