ING4 抗体 (Isoform 1)
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北京 101111
Quick Overview for ING4 抗体 (Isoform 1) (ABIN118054)
抗原
See all ING4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 164-175, Isoform 1
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序列
- Protein sequence for Human p29 ING4 isoform 1, 249 aa, predicted MW 28.5 kDa: 1 maagmylehy ldsienlpfe lqrnfqlmrd ldqrtedlka eidklateym ssarslssee 61 klallkqiqe aygkckefgd dkvqlamqty emvdkhirrl dtdlarfead lkekqiessd 121 ydsssskgkk kgrtqkekka ararskgkns deeapktaqk klklvrtspe ygmpsvtfgs 181 vhpsdvldmp vdpneptycl chqvsygemi gcdnpdcsie wfhfacvglt tkprgkwfcp 241 rcsqerkkk Protein sequence for Human p29 ING4 isoform 2, 47 aa, predicted MW 5.6 kDa: 1 maagmylehy ldsienlpfe lqrnfqlmrd ldqrteeald tissleh
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特异性
- Reactivity occurs against human p29 ING4 protein. 100 % homology is on record for this protein from human, dog, rat, and mouse. Cross reactivity with p29 ING4 protein from chimpanzee and chicken sources is also expected based on high homology (one amino acid change in sequence) by BLAST. Reactivity with p29 ING4 proteins from other sources is not known.
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纯化方法
- Immunoaffinity chromatography.
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免疫原
- A synthetic peptide corresponding aa 164-175 of Human p29 ING4 protein. This sequence only shows homology to isoform 1 for ING4. Genename: ING4
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anti-Inhibitor of Growth Family, Member 4 (ING4) (AA 1-249) antibody
ING4 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 4 (ING4) (AA 1-249) antibodyING4 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 4 (ING4) (AA 1-249) antibodyING4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 8F7 unconjugated
anti-Inhibitor of Growth Family, Member 4 (ING4) (AA 1-190) antibodyING4 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 4 (ING4) (AA 110-159) antibodyING4 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 猴, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 4 (ING4) (AA 162-195), (C-Term) antibodyING4 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB47839 unconjugated
anti-Inhibitor of Growth Family, Member 4 (ING4) (AA 75-249) antibodyING4 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 4 (ING4) (Internal Region) antibodyING4 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 4 (ING4) (Internal Region) antibodyING4 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 4 (ING4) (AA 150-175) antibodyING4 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
- Antibody R1606P has been tested for use in ELISA (1: 3,000-1: 12,000) against theimmunizing peptide. Specific conditions for Western blotting (1: 500-1: 3,000) reactivity
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限制
- 仅限研究用
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浓度
- 1.28 mg/mL (by UV absorbance at 280 nm)
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缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, containing 0.01 % (w/v) Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- This product is photosensitive and should be protected from light
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储存条件
- 4 °C
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储存方法
- Store undiluted at 2-8 °C. DO NOT FREEZE!
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: "[Impact of Donor KIR2DS5 Genotype on Outcome Following Haploidentical Hematopoietic Stem Cell Transplantation.]" in: Zhongguo shi yan xue ye xue za zhi / Zhongguo bing li sheng li xue hui = Journal of experimental hematology / Chinese Association of Pathophysiology, Vol. 16, Issue 1, pp. 111-5, (2008) (PubMed).
: "Endometrial stromal sarcoma of the small bowel: a case report and review of literature." in: Annals of diagnostic pathology, Vol. 12, Issue 2, pp. 128-33, (2008) (PubMed).
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- ING4 (Inhibitor of Growth Family, Member 4 (ING4))
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别名
- ING4
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背景
- P29 ING4 is a tumor suppressor protein similar to ING1 that may inhibit tumor progression by modulating the transcriptional output of signaling pathways which regulate cell proliferation. p29 ING4 has been shown to suppress brain tumor angio-genesis through transcriptional repression of RelA/ NFKB3 target genes when complexed with RelA. p29 ING4 may also specifically suppress loss of contact inhibition elicited by activated oncogenes such as MYC. p29 ING4 shows a nuclear localization and interacts with EP300, TP53, RelA, inhibits cell growth, and induces apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. Multiple alternatively spliced transcript variants have been observed. The accession number listed below is for variant (1) that encodes the longest isoform.Synonyms: Inhibitor of growth protein 4, My036, p29ING4
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基因ID
- 51147
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NCBI登录号
- NP_001121054
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UniProt
- Q9UNL4
抗原
-
