Smooth Muscle Actin 抗体 (N-Term)
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Quick Overview for Smooth Muscle Actin 抗体 (N-Term) (ABIN114405)
抗原
See all Smooth Muscle Actin (ACTA2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- N-Term
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特异性
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This antibody is specific to alpha-smooth isoform of actin. It reacts with smooth muscle cells of vessels and different parenchymes. The antibody does not cross-react with beta and gamma-cytoplasmic, alpha-sarcomeric and alpha-myocardial actin isoforms.
Cellular Localization: Cytoplasmic. -
纯化方法
- Purified
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免疫原
- N-terminal decapeptide of alpha-smooth muscle Actin
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亚型
- IgG2a
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应用备注
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Immunohistochemistry on Formalin Fixed Paraffin Embedded Sections: Use Actin antibodyat 1/25-1/50 dilution in an ABC method for 30 minutes at room temperature. Recommended Positive Control: Leiomyoma.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- Smooth Muscle Actin (ACTA2) (Actin, alpha 2, Smooth Muscle, Aorta (ACTA2))
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背景
- Smooth muscle actin is expressed in normal smooth muscle and in myoepithelial cells, and also in tumours derived from these cells. Actins are involved in maintaining the structure and integrity of a cell, as well as cell motility. They are highly conserved proteins and make up the majority of the contractile apparatus. To date, six different actin isoforms have been described.Synonyms: ACTSA, ACTVS, Alpha-actin-2, Cell growth-inhibiting gene 46 protein
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基因ID
- 59
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NCBI登录号
- NP_001135417
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UniProt
- P62736
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途径
- Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development
抗原
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