anti-Hematopoietic Prostaglandin D Synthase (HPGDS) 抗体

Prostaglandin-D synthase is a sigma class glutathione-S-transferase family member. 再加上,我们可以发HPGDS 蛋白 (10)HPGDS 试剂盒 (7)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
HPGDS 27306 O60760
HPGDS 54486 Q9JHF7
HPGDS 58962 O35543

antibodies-online.cn销售最多的anti-HPGDS 抗体

Showing 10 out of 21 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 WB 50 μg Log in to see 29至35个工作日
非结合性 WB Western blot analysis of HPGDS expression in THP1 (A), Raw264.7 (B), PC12 (C) whole cell lysates. 200 μL Log in to see 7至8个工作日
非结合性 IHC (p), WB Anti-HPGDS / PGDS antibody IHC staining of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN958991 concentration 5 ug/ml. 50 μg Log in to see 29至35个工作日
大鼠 非结合性 IHC (p), WB Human Thymus (formalin-fixed, paraffin-embedded) stained with PGDS antibody ABIN337149 at 10 ug/ml followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 29至35个工作日
非结合性 ICC, IHC, IP, WB 100 μg Log in to see 7至10个工作日
小鼠 非结合性 ICC, IHC, IP, WB 100 μg Log in to see 7至10个工作日
非结合性 IHC, IHC (p), WB Western Blot: HPGDS Antibody [NBP1-54625] - Titration: 0.2-1 ug/ml, Positive Control: Human Spleen. Immunohistochemistry-Paraffin: HPGDS Antibody [NBP1-54625] - Human Lung tissue, 5ug/ml. 100 μL Log in to see 26至33个工作日
非结合性 ICC, IF, IHC, IHC (p) Immunocytochemistry/Immunofluorescence: HPGDS Antibody [NBP1-83322] Staining of human cell line A-431 shows positivity in nucleus but not nucleoli & cytoplasm. Immunohistochemistry-Paraffin: HPGDS Antibody [NBP1-83322] - Staining of human bone marrow shows moderate cytoplasmic positivity in megakaryocytes. 0.1 mL Log in to see 28至35个工作日
非结合性 IHC, WB   200 μL Log in to see 29至35个工作日
非结合性 WB   100 μL Log in to see 29至35个工作日

通过反应活性、应用领域、克隆类型和共轭标记 HPGDS 抗体

特性 应用范围 宿主 克隆类型
Human , ,
Mouse (Murine)
Rat (Rattus)


Human Hematopoietic Prostaglandin D Synthase (HPGDS) interaction partners

  1. the development of a competition binding assay amenable to high-throughput screening (HTS (显示 APCDD1 抗体)) in a scintillation proximity assay (SPA (显示 FASL 抗体)) format. This assay was used to screen an in-house compound library of approximately 280,000 compounds for novel H-PGDS inhibitors.

  2. The effect of C. molle alkaloid extract on H-PGDS was studied. The alkaloid extract exhibited a 70% inhibition on H-PGDS with an IC50 of 13.7 mug/ml.

  3. the Val187Ile HPGDS isoenzyme common among African Americans is not associated with colorectal cancer risk

  4. COX-1 and H-PGDS were rapidly ubiquitinated and degraded through the ubiquitin-proteasome system in response to the elevation of the intracellular calcium level

  5. In patients with mixed atrophy, testicular mast cell numbers and phenotypes change with respect to the ability to express COX2 (显示 COX2 抗体) and PGDS (显示 PTGDS 抗体)-H.

  6. New polymorphisms of haematopoietic prostaglandin D synthase (显示 PTGDS 抗体)

  7. Data suggest that the suppressive effect of hematopoietic prostaglandin D synthase on lung injury could be partly mediated by edema formation and inhibition of genes involved in fibrosis.

  8. X-ray structure of human H-PGDS complexed with an inhibitor, 2-(2'-benzothiazolyl)-5-styryl-3-(4'-phthalhydrazidyl) tetrazolium chloride (BSPT) at 1.9 A resolution in the presence of Mg(2 (显示 MUC7 抗体)+).

  9. PU.1 cooperates with MAPK (显示 MAPK1 抗体)-activated cJun (显示 JUN 抗体) to maximally induce L-PGDS (显示 PTGDS 抗体) expression in macrophages.

Mouse (Murine) Hematopoietic Prostaglandin D Synthase (HPGDS) interaction partners

  1. H-PGDS deficiency accelerates the production of SDF-1alpha and the activity of MMP-9 (显示 MMP9 抗体) in the antigen-stimulated intestine. SDF-1alpha receptor blockade or MMP-9 (显示 MMP9 抗体) inhibition relieves the exacerbated mast cell hyperplasia and manifestations observed in H-PGDS(-/-).

  2. HPGDS may play a role in the regulation of inflammation and epithelial cell health within the oviduct.

  3. Data suggest a role for hematopoietic prostaglandin D synthase-produced prostaglandin D(2) in the initial nuclear translocation of SOX9 (显示 SOX9 抗体).

  4. These data suggest that PGD(2) generated via HPGDS has detrimental effects after spinal cord injury and that blocking the activity of this enzyme can be beneficial.

  5. hPGD (显示 HPGD 抗体)(2)S-derived cyclopentenone prostaglandins may protect against inflammatory diseases, where T lymphocytes play a pathogenic role, as in rheumatoid arthritis, atopic eczema, and chronic rejection

  6. Our results demonstrated that the neuroprotective effects of HPGDS in our model are mediated by suppression of activation and infiltration of inflammatory cells.

HPGDS 抗原简介


Prostaglandin-D synthase is a sigma class glutathione-S-transferase family member. The enzyme catalyzes the conversion of PGH2 to PGD2 and plays a role in the production of prostanoids in the immune system and mast cells. The presence of this enzyme can be used to identify the differentiation stage of human megakaryocytes.

Gene names and symbols associated with HPGDS

  • hematopoietic prostaglandin D synthase (hpgds) 抗体
  • hematopoietic prostaglandin D synthase (HPGDS) 抗体
  • hematopoietic prostaglandin D synthase (Hpgds) 抗体
  • GSTS 抗体
  • GSTS1-1 抗体
  • H-PGDS 抗体
  • PGD2 抗体
  • PGDS 抗体
  • Ptgds2 抗体
  • XlGSTS1 抗体

Protein level used designations for HPGDS

prostaglandin D2 synthase, hematopoietic , GST class-sigma , glutathione S-transferase sigma , glutathione-dependent PGD synthase , glutathione-dependent PGD synthetase , glutathione-requiring prostaglandin D synthase , hematopoietic prostaglandin D2 synthase , prostaglandin-H2 D-isomerase , H-PGDS , glutathione S-transferase , prostaglandin-D synthase , prostaglandin D2 synthase 2, hematopoietic

448666 Xenopus (Silurana) tropicalis
27306 Homo sapiens
395863 Gallus gallus
54486 Mus musculus
58962 Rattus norvegicus
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