ROR1 抗体
(Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1))
This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2012].
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Latest Publications for our ROR1 抗体
: "ROR1-CAVIN3 interaction required for caveolae-dependent endocytosis and pro-survival signaling in lung adenocarcinoma." in: Oncogene, Vol. 38, Issue 26, pp. 5142-5157, (2019) (PubMed).: "Interaction between ROR1 and MuSK activation complex in myogenic cells." in: FEBS letters, Vol. 592, Issue 3, pp. 434-445, (2019) (PubMed).
: "Antibody-drug conjugate T-DM1 treatment for HER2+ breast cancer induces ROR1 and confers resistance through activation of Hippo transcriptional coactivator YAP1." in: EBioMedicine, Vol. 43, pp. 211-224, (2019) (PubMed).
: "Silencing ROR1 and ROR2 inhibits invasion and adhesion in an organotypic model of ovarian cancer metastasis." in: Oncotarget, Vol. 8, Issue 68, pp. 112727-112738, (2018) (PubMed).
: "Maintenance and pharmacologic targeting of ROR1 protein levels via UHRF1 in t(1;19) pre-B-ALL." in: Oncogene, Vol. 37, Issue 38, pp. 5221-5232, (2018) (PubMed).
: "A receptor tyrosine kinase ROR1 inhibitor (KAN0439834) induced significant apoptosis of pancreatic cells which was enhanced by erlotinib and ibrutinib." in: PLoS ONE, Vol. 13, Issue 6, pp. e0198038, (2018) (PubMed).
: "ROR1 and ROR2 play distinct and opposing roles in endometrial cancer." in: Gynecologic oncology, Vol. 148, Issue 3, pp. 576-584, (2018) (PubMed).
: "ROR1 sustains caveolae and survival signalling as a scaffold of cavin-1 and caveolin-1." in: Nature communications, Vol. 7, pp. 10060, (2016) (PubMed).
: "Targeting the ROR1 and ROR2 receptors in epithelial ovarian cancer inhibits cell migration and invasion." in: Oncotarget, Vol. 6, Issue 37, pp. 40310-26, (2015) (PubMed).
: "Targeting ROR1 inhibits epithelial-mesenchymal transition and metastasis." in: Cancer research, Vol. 73, Issue 12, pp. 3649-60, (2013) (PubMed).
Aliases for ROR1 抗体
receptor tyrosine kinase like orphan receptor 1 (ROR1) 抗体receptor tyrosine kinase-like orphan receptor 1 (Ror1) 抗体
receptor tyrosine kinase like orphan receptor 1 (Ror1) 抗体
receptor tyrosine kinase-like orphan receptor 1 (ror1) 抗体
2810404D04Rik 抗体
dJ537F10.1 抗体
fi34e02 抗体
mRor1 抗体
NTRKR1 抗体
Ntrkr1 抗体
RGD1559469 抗体
ROR1 抗体
si:dkey-209n16.1 抗体
wu:fi34e02 抗体
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