IgG1 Fc (AA 104-330) 蛋白
Quick Overview for IgG1 Fc (AA 104-330) 蛋白 (ABIN7274867)
抗原
蛋白类型
宿主
资源
纯度
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产品特性
- AA 104-330
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原理
- Human IgG1 Fc Protein
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序列
- Asp104-Lys330
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产品特性
- Recombinant Human IgG1 Fc is expressed from HEK293 without tag.It contains Asp104-Lys330.
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过滤
- 0.22 μm filtered
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内毒素水平
- Less than 1EU per μg by the LAL method.
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Biological Activity Comment
- The affinity constant of 0.283 μM as determined in SPR assay (Biacore T200). See testing image for detail.
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IgG1 Fc (AA 98-324) protein
宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
IgG1 Fc protein (Fc Tag)宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE
IgG1 Fc (AA 100-330) protein (DYKDDDDK Tag)宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
IgG1 Fc (AA 100-330) protein (gD Tag)宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
IgG1 Fc (AA 98-324) protein (AVI tag,Biotin)宿主: 小鼠 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
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缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
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储存条件
- -20 °C,-80 °C
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储存方法
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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有效期
- 12 months
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- IgG1 Fc
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背景
- IgG1 is most abundant in serum among the four IgG subclasses (IgG1, 2, 3 and 4) and binds to Fc receptors (FcγR) on phagocytic cells with high affinity. Fc fragment is demonstrated to mediate phagocytosis, trigger inflammation, and target Ig to particular tissues.IgG1 Fc was reported has a novel role as a potential anti-inflammatory drug for treatment of human autoimmune diseases.
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分子量
- 25.5 kDa. Due to glycosylation, the protein migrates to 31-33 kDa based on Tris-Bis PAGE result.
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UniProt
- P01857-1
抗原
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