YWHAE 蛋白
Quick Overview for YWHAE 蛋白 (ABIN7194064)
抗原
See all YWHAE 蛋白蛋白类型
宿主
资源
纯度
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原理
- Recombinant Human 14-3-3 epsilon/YWHAE Protein
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序列
- Met 1-Gln 255
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产品特性
- A DNA sequence encoding the human YWHAE (NP_006752.1) (Met 1-Gln 255) was expressed, with two additional amino acids (Gly & Pro) at the N-terminus.
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!探索我们的预定义定制蛋白和定制蛋白服务！Product表达系统ConjugateOrigin价格从表达系统 HEK-293 CellsConjugate His tagOrigin Human价格从 115,504.49 ¥表达系统 Cell-free protein synthesis (CFPS)Conjugate Strep TagOrigin Human价格从 172,528.32 ¥您的项目需要进一步定制吗？联系我们，了解我们的定制蛋白解决方案
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14-3-3 epsilon (YWHAE) (AA 1-255) protein (His tag)
custom-made YWHAE 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
14-3-3 epsilon (YWHAE) (AA 1-255) protein (His tag)custom-made YWHAE 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
14-3-3 epsilon (YWHAE) (AA 1-255) protein (His tag)YWHAE 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
14-3-3 epsilon (YWHAE) (AA 1-255) protein (GST tag)YWHAE 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
14-3-3 epsilon (YWHAE) protein (GST tag)YWHAE 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % as determined by SDS-PAGE
14-3-3 epsilon (YWHAE) (AA 1-255) proteinYWHAE 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % pure SDS
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from sterile 20 mM Tris, 150 mM NaCl, 0.25 mM DTT, 25 % glycerol, 0.5 mM GSH, pH 7.5
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- YWHAE (14-3-3 epsilon (YWHAE))
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别名
- 14-3-3 epsilon/YWHAE
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背景
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Background: YWHAE, also known as 14-3-3 epsilon, mediate signal transduction by binding to phosphoserine-containing proteins. 14-3-3 epsilon / YWHAE is a member of the 14-3-3 proteins family. 14-3-3 proteins are a group of highly conserved proteins that are involved in many vital cellular processes such as metabolism, protein trafficking, signal transduction, apoptosis and cell cycle regulation. 14-3-3 proteins are mainly localized in the synapses and neuronal cytoplasm, and seven isoforms have been identified in mammals. This family of proteins was initially identified as adaptor proteins which bind to phosphoserine-containing motifs. Binding motifs and potential functions of 14-3-3 proteins are now recognized to have a wide range of functional relevance. 14-3-3 epsilon / YWHAE is found in both plants and mammals, and this protein is 100 % identical to the mouse ortholog. YWHAE interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. 14-3-3 epsilon / YWHAE is implicated in the regulation of a large spectrum of both general and specialized signaling pathways. 14-3-3 epsilon / YWHAE Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. This Binding generally results in the modulation of the activity of the binding partner.
Synonym: 14-3-3E,HEL2,KCIP-1,MDCR,MDS
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分子量
- 29.4 kDa
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NCBI登录号
- NP_006752
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途径
- Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, M Phase
抗原
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