CD38 Protein (AA 44-301) (His tag)
Our Local Distributor
北京 101111
Quick Overview for CD38 Protein (AA 44-301) (His tag) (ABIN6253545)
抗原
See all CD38 蛋白蛋白类型
宿主
资源
纯度
-
-
产品特性
- AA 44-301
-
标记
- This CD38 protein is labelled with His tag.
-
序列
- AA 44-301
-
内毒素水平
- Less than 1.0 EU per μg by the LAL method.
-
-
-
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
- 50 mM MES, 100 mM NaCl, pH 6.5
-
注意事项
- Please avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
-
- CD38
-
背景
- CD antigen CD38 is also known as ADP-ribosyl cyclase 1, which belongs to the ADP-ribosyl cyclase family. CD38 is expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. These reaction products are essential for the regulation of intracellular Ca2+. The loss of CD38 function is associated with impaired immune responses, metabolic disturbances, and behavioral modifications. The CD38 protein is a marker of cell activation. It has been connected to HIV infection, leukemias, myelomas, solid tumors, type II diabetes mellitus and bone metabolism. CD38 has been used as a prognostic marker in leukemia.
-
分子量
- 31.8 kDa
-
NCBI登录号
- NP_001274206
抗原
-