Ubiquitin-Conjugating Enzyme E2K (UBE2K) (Middle Region) Peptide
UBE2K
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN985825
发货至:
中国
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Contact Info
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Quick Overview for Ubiquitin-Conjugating Enzyme E2K (UBE2K) (Middle Region) Peptide (ABIN985825)
抗原
UBE2K
(Ubiquitin-Conjugating Enzyme E2K (UBE2K))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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产品特性
- This is a synthetic peptide designed for use in combination with anti-UBE2K antibody (Catalog #: ARP43049_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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Ubiquitin-Conjugating Enzyme E2K (UBE2K) peptide
UBE2K 适用: 人, Cow, 犬, 小鼠, Pig 宿主: 合成 BP, Imm
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))
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背景
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UBE2K belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene.
Alias Symbols: DKFZp564C1216, DKFZp686J24237, E2-25K, HIP2, HYPG, LIG, UBC1
Protein Interaction Partner: HTT,HTT,NEDD8,NFKB1,PIAS4,TP53,TRIM3,DDX58,DSTYK,HTT,RNF2,UBE2I
Protein Size: 200 -
分子量
- 22 kDa
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基因ID
- 3093
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NCBI登录号
- NM_005339, NP_005330
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UniProt
- P61086
抗原
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