Transmembrane Protein 173 (TMEM173) (Middle Region) Peptide
TMEM173
适用: 人
宿主: 合成
BP, WB
Quick Overview for Transmembrane Protein 173 (TMEM173) (Middle Region) Peptide (ABIN985225)
抗原
STING/TMEM173 (TMEM173)
(Transmembrane Protein 173 (TMEM173))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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序列
- DPNIRFLDKL PQQTGDHAGI KDRVYSNSIY ELLENGQRAG TCVLEYATPL
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产品特性
- This is a synthetic peptide designed for use in combination with anti-TMEM173 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
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背景
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This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.
Alias Symbols: ERIS, MITA, MPYS, SAVI, NET23, STING, hMITA, hSTING
Protein Size: 379 -
分子量
- 42 kDa
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基因ID
- 340061
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NCBI登录号
- NM_198282, NP_938023
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UniProt
- Q86WV6
抗原
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