Protein Arginine Methyltransferase 7 (PRMT7) (C-Term) Peptide
PRMT7
适用: 小鼠
宿主: 合成
BP, WB
Quick Overview for Protein Arginine Methyltransferase 7 (PRMT7) (C-Term) Peptide (ABIN982241)
抗原
PRMT7
(Protein Arginine Methyltransferase 7 (PRMT7))
宿主
小鼠
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- C-Term
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序列
- GEINDQDRTD HYAQALRTVL LPGSVCLCVS DGSLLSMLAH HLGAEQVFTV
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产品特性
- This is a synthetic peptide designed for use in combination with anti-Prmt7 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PRMT7 (Protein Arginine Methyltransferase 7 (PRMT7))
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背景
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Prmt7 is a arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. It specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3), such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. It plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these sites. It may also play a role in embryonic stem cell (ESC) pluripotency. It also able to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro, the relevance of such results is however unclear in vivo.
Alias Symbols: 4933402B05Rik, BC006705, MGC7929
Protein Size: 692 -
分子量
- 78 kDa
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基因ID
- 214572
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NCBI登录号
- NM_145404, NP_663379
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UniProt
- Q922X9
抗原
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