phosphodiesterase 5A, cGMP-Specific (PDE5A) (C-Term) Peptide
PDE5A
适用: 人
宿主: 合成
BP, WB, IHC
Quick Overview for phosphodiesterase 5A, cGMP-Specific (PDE5A) (C-Term) Peptide (ABIN981513)
抗原
PDE5A
(phosphodiesterase 5A, cGMP-Specific (PDE5A))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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蛋白结构域
- C-Term
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序列
- TACDLSAITK PWPIQQRIAE LVATEFFDQG DRERKELNIE PTDLMNREKK
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产品特性
- This is a synthetic peptide designed for use in combination with anti-PDE5A Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PDE5A (phosphodiesterase 5A, cGMP-Specific (PDE5A))
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背景
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This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms.
Alias Symbols: CGB-PDE, CN5A, PDE5, PDE5A1
Protein Interaction Partner: CASP3,PRKG1
Protein Size: 823 -
分子量
- 93 kDa
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基因ID
- 8654
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NCBI登录号
- NM_033437, NP_246273
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UniProt
- O76074
抗原
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